Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   BSR20_RS08620 Genome accession   NZ_CP018189
Coordinates   1871713..1872453 (+) Length   246 a.a.
NCBI ID   WP_156209945.1    Uniprot ID   -
Organism   Streptococcus salivarius strain ICDC3     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1866713..1877453
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BSR20_RS10495 (BSR20_08680) - 1868187..1868438 (+) 252 Protein_1645 bacteriocin ABC transporter ATP-binding protein -
  BSR20_RS08595 - 1868491..1869620 (-) 1130 Protein_1646 IS3 family transposase -
  BSR20_RS08600 (BSR20_08695) - 1869720..1870652 (-) 933 WP_156209941.1 thioredoxin family protein -
  BSR20_RS08605 (BSR20_08700) - 1870818..1870997 (-) 180 WP_156209942.1 bacteriocin transporter -
  BSR20_RS08610 (BSR20_08705) - 1871035..1871286 (-) 252 WP_156209943.1 bacteriocin immunity protein -
  BSR20_RS08615 (BSR20_08710) - 1871252..1871476 (-) 225 WP_156209944.1 leucocin A/sakacin P family class II bacteriocin -
  BSR20_RS08620 (BSR20_08715) comE/blpR 1871713..1872453 (+) 741 WP_156209945.1 LytR/AlgR family response regulator transcription factor Regulator
  BSR20_RS10600 (BSR20_08720) - 1872538..1872939 (-) 402 WP_156209946.1 hypothetical protein -
  BSR20_RS10390 - 1873269..1873436 (-) 168 WP_197090282.1 hypothetical protein -
  BSR20_RS08635 (BSR20_08730) - 1873895..1873984 (-) 90 WP_073688908.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  BSR20_RS08640 (BSR20_08735) - 1874307..1874486 (-) 180 WP_021152528.1 Blp family class II bacteriocin -
  BSR20_RS08645 (BSR20_08740) - 1874647..1876392 (-) 1746 WP_156209948.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 246 a.a.        Molecular weight: 28291.91 Da        Isoelectric Point: 9.2009

>NTDB_id=173772 BSR20_RS08620 WP_156209945.1 1871713..1872453(+) (comE/blpR) [Streptococcus salivarius strain ICDC3]
MKIYLLEDNPIQMGRLENALAQELKTFGKNLSCVHSFDKPDQLLSAITSNISDQVFFLDIEIKGEKLKGLDIAKIIRGKN
PYATIIFVATHSEYMPLVFDYQVSALDYIDKSLSEIEFRKKITRALAITMKPLGIENGEIFDFQTQHTAIRIPLNQVIYI
ETSPQKHYVILHGTNNQMTFRANLKDLEKASPSLVSCHRSYLINPYNIIRINKLKREVEMTDGSICPFSRTKAKMLMDTF
NRRKLD

Nucleotide


Download         Length: 741 bp        

>NTDB_id=173772 BSR20_RS08620 WP_156209945.1 1871713..1872453(+) (comE/blpR) [Streptococcus salivarius strain ICDC3]
ATGAAGATTTACTTATTAGAAGATAATCCTATTCAGATGGGACGTTTAGAAAATGCTCTAGCTCAGGAACTTAAGACCTT
CGGAAAAAATCTATCGTGTGTTCACTCTTTTGACAAGCCAGATCAACTACTATCTGCTATCACCTCAAATATAAGCGATC
AGGTTTTCTTTCTGGATATTGAAATTAAAGGAGAGAAATTAAAAGGGCTTGACATTGCCAAAATCATTAGAGGAAAAAAT
CCCTATGCTACTATTATCTTTGTCGCTACTCACTCAGAGTATATGCCACTAGTTTTTGATTACCAAGTATCTGCCCTAGA
CTATATCGACAAAAGTCTCTCTGAAATAGAATTTAGAAAAAAGATAACCAGAGCTTTAGCTATAACTATGAAACCACTTG
GGATAGAAAATGGCGAGATTTTTGATTTTCAAACACAACATACAGCTATTCGCATCCCTTTGAATCAAGTTATTTATATT
GAAACTTCTCCACAAAAGCATTATGTGATACTTCATGGTACAAACAACCAAATGACCTTTCGTGCAAATCTAAAGGACCT
TGAAAAAGCTAGTCCTTCACTCGTATCTTGCCACCGTTCATATCTTATTAACCCATACAACATTATAAGAATCAACAAAT
TAAAGCGTGAAGTCGAAATGACTGATGGCAGTATCTGTCCTTTTTCACGTACCAAAGCTAAGATGCTGATGGATACTTTT
AATCGAAGAAAGCTTGACTAG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-122)

LytTr DNA-binding domain (LytTR)

(150-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

42.553

95.528

0.407
  comE/comE2 Streptococcus equinus JB1

37.975

96.341

0.366