Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   BSR19_RS07465 Genome accession   NZ_CP018187
Coordinates   1662478..1663122 (-) Length   214 a.a.
NCBI ID   WP_002891417.1    Uniprot ID   J7TMS3
Organism   Streptococcus salivarius strain ICDC2     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1657478..1668122
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BSR19_RS07440 (BSR19_07555) - 1659556..1660554 (-) 999 WP_156246931.1 NAD(P)/FAD-dependent oxidoreductase -
  BSR19_RS07445 (BSR19_07560) trmD 1660556..1661275 (-) 720 WP_060972852.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  BSR19_RS07450 (BSR19_07565) rimM 1661265..1661783 (-) 519 WP_156246932.1 ribosome maturation factor RimM -
  BSR19_RS07465 (BSR19_07580) vraR 1662478..1663122 (-) 645 WP_002891417.1 response regulator transcription factor Regulator
  BSR19_RS07470 (BSR19_07585) - 1663112..1664122 (-) 1011 WP_002891418.1 sensor histidine kinase -
  BSR19_RS07475 (BSR19_07590) liaF 1664119..1664816 (-) 698 Protein_1433 cell wall-active antibiotics response protein LiaF -
  BSR19_RS07480 (BSR19_07595) - 1664980..1665738 (-) 759 WP_156246933.1 potassium channel family protein -
  BSR19_RS07485 (BSR19_07600) stkP/pknB 1665885..1667759 (-) 1875 WP_156246934.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24007.33 Da        Isoelectric Point: 4.5814

>NTDB_id=173642 BSR19_RS07465 WP_002891417.1 1662478..1663122(-) (vraR) [Streptococcus salivarius strain ICDC2]
MSNKINVILVDDHEMVRLGLKSFLNLQGDVEVVGEASNGREGVDLALELRPDVVVMDLVMPELDGVQATLELLKEWPEAK
ILVLTSYLDNEKIYPVIEAGAKGYMLKTSSAAEILNSIRKVYRGEEAIETEVDNKIKYHDSHPDLHDDLTARERDILALL
AKGYDNQTIANELFISLKTVKTHVSNILGKLNVDDRTQAVVYAFRHHLVSQDDE

Nucleotide


Download         Length: 645 bp        

>NTDB_id=173642 BSR19_RS07465 WP_002891417.1 1662478..1663122(-) (vraR) [Streptococcus salivarius strain ICDC2]
ATGTCGAATAAGATAAATGTGATTTTGGTCGATGACCATGAGATGGTCCGTTTGGGCCTTAAGAGTTTCCTGAATCTCCA
AGGAGATGTCGAAGTGGTTGGAGAAGCGAGCAATGGCCGAGAAGGTGTTGACCTTGCCCTGGAACTTCGTCCAGATGTCG
TCGTAATGGACCTTGTCATGCCTGAATTAGATGGTGTTCAAGCGACTTTGGAATTGCTCAAAGAATGGCCAGAGGCCAAG
ATTTTGGTTTTGACTAGCTATTTGGACAATGAAAAAATTTATCCAGTCATTGAAGCTGGTGCTAAAGGTTATATGCTTAA
AACTAGCAGTGCGGCAGAGATTCTCAATAGTATTCGTAAGGTTTACCGTGGTGAAGAAGCTATCGAAACAGAGGTGGACA
ATAAGATTAAATACCACGATAGCCACCCGGACCTACACGACGACTTAACGGCACGTGAACGTGATATCCTGGCGCTTTTG
GCTAAGGGTTATGACAATCAGACCATTGCTAACGAGCTATTCATTTCATTGAAAACCGTTAAAACGCACGTGTCTAATAT
CCTAGGAAAACTCAATGTTGATGACCGTACTCAGGCTGTCGTTTATGCCTTTAGACATCATTTGGTTTCACAGGATGATG
AATAA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-203)

Response regulator receiver domain (Response_reg)

(7-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB J7TMS3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

50.485

96.262

0.486
  degU Bacillus subtilis subsp. subtilis str. 168

36.161

100

0.379