Detailed information NTG0173578

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: BSR19_RS00330
• Genome accession: NZ_CP018187
• Coordinates: 55539..58070 (+)
• Length: 843 a.a.
• NCBI ID: WP_414820569.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain ICDC2
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 50539..63070

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BSR19_RS00310 (BSR19_00310)	purB	50711..52009 (+)	1299	WP_060972888.1	adenylosuccinate lyase	-
BSR19_RS00315 (BSR19_00315)	argS	52886..54577 (-)	1692	WP_060972889.1	arginine--tRNA ligase	-
BSR19_RS00320 (BSR19_00320)	argR	54732..55160 (+)	429	WP_171963598.1	arginine repressor	-
BSR19_RS00325 (BSR19_00325)	-	55160..55519 (+)	360	WP_060972890.1	YlbF family regulator	-
BSR19_RS00330 (BSR19_00330)	hexA	55539..58070 (+)	2532	WP_414820569.1	DNA mismatch repair protein MutS	Machinery gene
BSR19_RS00335 (BSR19_00335)	-	58104..58559 (-)	456	WP_060972892.1	DUF3021 domain-containing protein	-
BSR19_RS00340 (BSR19_00340)	-	58556..58993 (-)	438	WP_013989911.1	LytTR family DNA-binding domain-containing protein	-
BSR19_RS00345 (BSR19_00345)	-	59172..59477 (+)	306	WP_037603797.1	hypothetical protein	-
BSR19_RS00350 (BSR19_00350)	hexB	59529..61466 (+)	1938	WP_060972893.1	DNA mismatch repair endonuclease MutL	Machinery gene
BSR19_RS00355 (BSR19_00355)	-	61597..61818 (+)	222	WP_037597288.1	hypothetical protein	-
BSR19_RS00360 (BSR19_00360)	ruvA	61975..62565 (+)	591	WP_060972894.1	Holliday junction branch migration protein RuvA	Machinery gene

Sequence

Protein

• Length: 843 a.a.
• Molecular weight: 94591.65 Da
• Isoelectric Point: 4.6518

>NTDB_id=173578 BSR19_RS00330 WP_414820569.1 55539..58070(+) (hexA) [Streptococcus salivarius strain ICDC2]
MQQYLDIKENYPDAFLLFRMGDFYELFYDDAVKAAQILEISLTSRNKNADNPIPMAGVPYHSAQAYIDVLVEMGYKVAIA
EQMEDPKQAVGVVKREVVQVITPGTVVDSSKPDNANNFLVAIDKVGSRFGLAYMDVSTGEFFATELDDFSSVCSEIQNLK
AREVVVGYDLPEADEQVLVKQLNLLLSKETEVYDDVHLIDTSLTDLESSVAGKLLQYVHRTQMRELSHLQKAQHYEIKDY
LQMSYATKSSLDLLENARTGKKHGSLFWLLDETKTAMGMRLLRTWIDRPLVNQATITERQNIIQVFLDNFFERSDLTESL
KGVYDIERLASRVSFGKANPKDLIQLGHTLAQVPVIKAILESFNDEALSRLLQELDALPELESLIRSAIDPDAPATITEG
GIIRAGFDETLDKYRKVMSEGTSWIADIEAKEREASGITTLKIDYNRKDGYYFHVTNSNLSLVPDHFFRKATLKNSERFG
TAELAKIEGEMLEAREKSSTLEYDIFMRVREQVERYIDRLQSLAKAIATVDVLQSLAVVAETNHYVRPVFNDEHRIVIDQ
GRHAVVEKVMGVQEYIPNTITFDSQTNIQLITGPNMSGKSTYMRQLALSVVMAQMGSYVPADSIDLPVFDAIYTRIGAAD
DLISGQSTFMVEMMEANQAIKRATPNSLIIFDELGRGTATYDGMALAQSIIEFIHDKVGAKTMFATHYHELTALSNTLTH
LVNVHVATLEKEGEVTFLHKIVDGPADKSYGIHVAKIAGLPAALLERADTILTQLEGDTVTIQPQEKVSPQEKPATETHV
NEQISLFDDFTENPVLQELRDLDIYNMTPMQVMMAVADLKQKL

Nucleotide

• Length: 2532 bp

>NTDB_id=173578 BSR19_RS00330 WP_414820569.1 55539..58070(+) (hexA) [Streptococcus salivarius strain ICDC2]
ATGCAGCAGTATTTGGATATCAAGGAAAATTATCCAGATGCTTTTTTGCTGTTTCGGATGGGGGATTTTTACGAATTATT
TTACGATGATGCCGTTAAGGCTGCTCAAATTTTGGAAATTAGCCTAACCAGTCGTAATAAGAACGCAGATAATCCCATTC
CTATGGCAGGTGTTCCTTATCATTCGGCTCAAGCCTATATTGATGTCTTGGTTGAGATGGGCTACAAAGTAGCCATTGCT
GAGCAGATGGAGGACCCTAAACAGGCTGTTGGCGTGGTTAAGCGTGAGGTAGTTCAGGTTATCACGCCAGGGACAGTGGT
TGACAGCTCTAAACCTGATAATGCCAACAATTTCTTAGTAGCCATTGACAAGGTTGGAAGTCGATTCGGCCTGGCCTATA
TGGATGTATCAACGGGTGAATTTTTTGCGACAGAGTTGGATGATTTTAGTTCAGTTTGCAGTGAAATTCAGAATCTTAAG
GCACGTGAAGTAGTCGTTGGGTATGATTTACCTGAAGCTGATGAACAAGTTTTGGTGAAGCAACTCAACCTGCTTCTCTC
CAAGGAAACGGAGGTTTACGATGATGTCCACTTGATTGACACTAGTTTGACAGATTTGGAAAGCAGTGTGGCGGGTAAAC
TTCTCCAGTATGTTCATCGTACTCAGATGCGAGAGCTCAGTCATTTACAAAAGGCTCAGCACTATGAGATTAAGGATTAC
TTGCAGATGTCCTATGCGACCAAGTCAAGTTTGGATTTACTGGAAAATGCTAGAACGGGCAAGAAACACGGATCTCTTTT
CTGGCTCTTGGATGAAACCAAGACAGCTATGGGAATGCGTCTCTTGCGAACTTGGATTGATCGTCCTTTAGTGAATCAAG
CCACTATCACCGAGCGTCAGAATATTATCCAAGTTTTCTTGGACAATTTCTTCGAGCGTAGTGACTTGACTGAGAGTCTA
AAAGGTGTTTACGATATTGAGCGACTGGCCAGTCGTGTTTCCTTTGGCAAGGCTAATCCAAAAGATTTGATTCAGCTAGG
TCATACTTTGGCTCAAGTACCGGTGATTAAGGCGATTTTGGAGTCCTTTAATGATGAGGCCTTGTCACGCCTTTTACAAG
AGTTAGATGCTCTGCCAGAATTAGAGAGTTTGATTCGGTCGGCTATTGATCCAGATGCTCCTGCAACCATTACAGAAGGT
GGCATTATCCGTGCTGGTTTTGATGAGACCTTGGACAAGTATCGCAAGGTGATGAGTGAGGGAACCTCATGGATCGCAGA
TATCGAAGCTAAAGAACGTGAAGCGTCTGGTATTACAACACTAAAGATTGATTATAACCGTAAAGATGGTTATTACTTCC
ATGTGACCAACTCTAACCTTAGCTTGGTTCCTGACCATTTCTTCCGCAAGGCAACTCTGAAAAATTCAGAGCGCTTTGGA
ACTGCTGAGTTGGCTAAAATTGAAGGTGAGATGCTTGAGGCGCGTGAAAAATCATCAACGCTAGAGTATGATATTTTCAT
GCGTGTCCGTGAGCAGGTGGAACGCTATATTGACCGTTTGCAATCTTTGGCTAAAGCTATTGCGACAGTCGATGTGCTTC
AGAGTCTAGCTGTTGTAGCAGAGACCAATCATTATGTTCGTCCTGTGTTCAATGATGAGCATCGTATTGTTATTGATCAA
GGCCGTCATGCAGTGGTTGAGAAGGTTATGGGCGTTCAAGAATACATTCCAAACACCATTACCTTTGACAGTCAGACCAA
TATTCAGCTCATCACAGGACCAAATATGAGTGGTAAATCCACCTATATGCGTCAGTTAGCCTTGTCAGTCGTTATGGCTC
AGATGGGGTCTTACGTGCCAGCAGATAGTATTGACTTGCCAGTTTTTGACGCCATCTATACACGTATTGGTGCTGCAGAT
GACCTGATTTCAGGCCAGTCGACCTTCATGGTTGAGATGATGGAGGCTAATCAGGCCATTAAGCGAGCGACACCTAATTC
CTTGATTATTTTTGATGAGTTGGGACGTGGGACAGCCACCTATGACGGTATGGCTCTGGCCCAGTCTATCATTGAGTTTA
TTCATGACAAGGTGGGGGCTAAAACCATGTTTGCGACCCATTATCATGAGTTGACAGCTCTGTCAAATACTTTGACACAC
CTTGTCAACGTTCATGTGGCGACACTTGAAAAGGAAGGTGAGGTGACTTTCCTTCACAAGATTGTCGATGGCCCAGCCGA
TAAATCTTATGGTATTCATGTGGCTAAGATTGCAGGTTTACCAGCAGCTTTACTGGAACGTGCTGACACCATCTTGACAC
AACTAGAGGGCGATACAGTTACCATCCAACCTCAGGAAAAGGTATCGCCTCAAGAGAAACCTGCCACTGAAACGCATGTC
AACGAGCAAATCTCTCTCTTTGATGATTTTACTGAAAATCCAGTTCTTCAAGAGTTGCGTGATTTGGACATTTACAATAT
GACACCTATGCAAGTCATGATGGCTGTAGCAGATTTAAAACAGAAACTATAA

Domains

Predicted by InterProScan.

• MutS domain II (MutS_II) (117-230)

• MutS domain V (MutS_V) (590-776)

• MutS domain I (MutS_I) (1-109)

• MutS family domain IV (MutS_IV) (406-496)

• MutS domain III (MutS_III) (247-537)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	74.021	100	0.74
mutS	Pseudomonas stutzeri strain ATCC 17587	35.963	100	0.368