Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   A0O21_RS08875 Genome accession   NZ_CP014699
Coordinates   1915510..1917951 (-) Length   813 a.a.
NCBI ID   WP_067064394.1    Uniprot ID   A0A172Q9G3
Organism   Streptococcus pantholopis strain TA 26     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1910510..1922951
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A0O21_RS11100 - 1911121..1911252 (-) 132 WP_257722077.1 hypothetical protein -
  A0O21_RS10940 - 1911481..1911624 (-) 144 WP_173644637.1 hypothetical protein -
  A0O21_RS08845 (A0O21_08845) - 1911746..1911973 (-) 228 WP_067064383.1 hypothetical protein -
  A0O21_RS08850 (A0O21_08850) - 1912168..1913040 (-) 873 WP_067064385.1 helix-turn-helix domain-containing protein -
  A0O21_RS08855 (A0O21_08855) - 1913653..1913832 (+) 180 WP_067064387.1 hypothetical protein -
  A0O21_RS08865 (A0O21_08865) tadA 1914107..1914580 (-) 474 WP_067064389.1 tRNA adenosine(34) deaminase TadA -
  A0O21_RS08870 (A0O21_08870) - 1914580..1915356 (-) 777 WP_067064391.1 MBL fold metallo-hydrolase -
  A0O21_RS08875 (A0O21_08875) clpC 1915510..1917951 (-) 2442 WP_067064394.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  A0O21_RS08880 (A0O21_08880) - 1917956..1918411 (-) 456 WP_067064395.1 CtsR family transcriptional regulator -
  A0O21_RS08885 (A0O21_08885) - 1918630..1919094 (+) 465 WP_067064397.1 COG2426 family protein -
  A0O21_RS08890 (A0O21_08890) tsf 1919236..1920276 (-) 1041 WP_067064399.1 translation elongation factor Ts -
  A0O21_RS08895 (A0O21_08895) rpsB 1920376..1921152 (-) 777 WP_067064401.1 30S ribosomal protein S2 -
  A0O21_RS11160 - 1922058..1922177 (+) 120 WP_193790052.1 class III lanthipeptide -
  A0O21_RS11165 - 1922234..1922374 (+) 141 WP_193790053.1 class III lanthipeptide -

Sequence

Protein


Download         Length: 813 a.a.        Molecular weight: 89987.29 Da        Isoelectric Point: 5.6561

>NTDB_id=173373 A0O21_RS08875 WP_067064394.1 1915510..1917951(-) (clpC) [Streptococcus pantholopis strain TA 26]
MSNYSFKMQEVFRLALYQAARYDSQYLESWHILLAMAFIPDSVAGLSLAEYEADVSLEEYEAAAILALGKVPKEQVEEVE
FIEQSPALKRLLQTADGISQVTGAKEIGTEHVLFAMLLNMDLLATRLLEMVGFKLKDDGESIRLLDLRKSLERQAGFTKE
DLKAIHGLRKPKKARPNNNFSDMMKPPGTAGELSDFTRDLTEMARQGRLEPVIGREKEISRMVQILSRKTKNNPVLVGDA
GVGKTALAYGLAQRIVSGAIPYELQDMKVLELDMMSVVAGTRFRGDFEERMNQIIADIEADGHIILFIDELHTIMGSGSG
IDSTLDAANILKPALARGSLRTLGATTQEEYQKHIEKDAALSRRFARVLIEEPSVEAAYEIVLGLKKSYEDYHNVVISDA
AALAAVKAARRYLTGKHLPDSAIDLLDEASAQVQNMVKKEAPAYLTPADEAILQGDFKKASQYLKEAAAVHLLEPTLVTE
DDIMSTLSKLSGIPVEKLTQADSKKYLNLEKELHKRVIGQDAAVSAISRAIRRNQSGIRTGRRPIGSFMFLGPTGVGKTE
LAKALAQVLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLLQV
LDDGMLTDSRGRQVDFSNTIIIMTSNLGATALRDDKTVGFGAKSVSQDYQAMQSRILEELKHAYRPEFLNRIDETVVFHS
LSQDDMRQIVKIMVAPLIRNLAEKGITLKFQPSALKYLAQDGYDSEMGARPLRRALQTQVEDRLSELVLSGELTSGRTVK
IGLSKGKLAFALA

Nucleotide


Download         Length: 2442 bp        

>NTDB_id=173373 A0O21_RS08875 WP_067064394.1 1915510..1917951(-) (clpC) [Streptococcus pantholopis strain TA 26]
ATGAGTAATTATTCGTTTAAAATGCAGGAGGTATTCAGACTGGCCCTCTATCAGGCTGCACGTTATGACAGCCAATATCT
TGAAAGCTGGCATATCTTGCTGGCCATGGCTTTTATTCCTGATTCTGTTGCAGGTCTCAGTCTTGCGGAGTATGAAGCTG
ATGTCAGTTTGGAGGAGTACGAAGCTGCTGCTATTTTGGCTCTTGGAAAAGTTCCTAAAGAACAAGTAGAGGAAGTTGAA
TTTATAGAGCAGTCTCCGGCTTTAAAGCGTCTGCTGCAGACGGCTGACGGAATCAGTCAGGTGACTGGAGCCAAAGAGAT
TGGTACAGAGCATGTTTTATTTGCTATGCTGCTGAATATGGATCTCCTTGCTACCCGACTTTTAGAAATGGTCGGCTTCA
AATTGAAAGATGATGGCGAATCTATCCGTTTATTGGATTTACGTAAATCTCTAGAGAGACAGGCAGGATTCACCAAAGAA
GACCTTAAGGCTATCCATGGCTTGCGTAAGCCCAAAAAAGCAAGACCGAACAATAATTTTTCTGATATGATGAAGCCGCC
GGGAACAGCAGGCGAGCTCTCCGATTTCACGCGCGATTTGACAGAAATGGCCCGCCAAGGGCGGCTGGAACCTGTTATCG
GCCGGGAAAAAGAAATCTCCCGTATGGTACAGATTCTCAGTCGGAAAACAAAAAACAATCCGGTCCTAGTCGGTGATGCC
GGAGTTGGGAAAACAGCTCTTGCTTACGGCTTAGCTCAGCGCATCGTAAGCGGAGCCATTCCCTATGAACTGCAGGATAT
GAAAGTTCTTGAACTGGATATGATGAGTGTGGTTGCCGGGACACGTTTCCGCGGGGACTTTGAAGAGCGGATGAACCAAA
TCATTGCGGATATTGAAGCAGATGGGCACATTATTCTCTTTATTGATGAACTGCATACGATTATGGGGTCTGGCAGCGGG
ATTGACAGCACGCTTGATGCAGCCAATATCCTTAAACCTGCCCTGGCACGTGGGAGTCTTCGGACACTTGGCGCAACAAC
TCAAGAGGAATATCAGAAGCATATCGAAAAGGATGCGGCTCTGTCCCGGCGCTTCGCCAGAGTACTGATTGAAGAGCCTA
GTGTAGAGGCAGCTTATGAGATTGTGCTTGGACTCAAAAAATCTTACGAAGATTATCACAATGTCGTTATTTCAGATGCA
GCTGCTCTGGCAGCGGTTAAAGCAGCCCGCCGCTATCTGACAGGAAAACATTTGCCTGATTCGGCGATTGACCTGTTGGA
TGAAGCGAGCGCACAGGTGCAAAACATGGTCAAAAAAGAAGCGCCTGCCTACTTAACTCCTGCTGATGAAGCGATTTTGC
AAGGAGATTTCAAAAAAGCTTCACAGTATTTAAAAGAGGCTGCAGCCGTTCATTTGCTAGAACCTACACTGGTGACAGAA
GATGATATTATGAGTACACTCAGCAAGCTGTCCGGAATTCCGGTCGAAAAACTGACTCAGGCTGATAGCAAAAAATATCT
TAATCTGGAAAAAGAGCTGCACAAGCGAGTTATTGGACAGGATGCTGCTGTTTCAGCTATCAGCCGGGCTATTCGCCGCA
ACCAGTCCGGGATTCGGACTGGCCGCCGTCCCATTGGTTCTTTTATGTTTTTAGGACCGACAGGTGTTGGGAAGACAGAG
CTGGCCAAAGCTTTAGCACAGGTTCTTTTTGATGATGAGTCGGCTCTTATTCGCTTTGATATGTCTGAATATATGGAAAA
ATTTGCAGCCAGCCGGCTCAACGGGGCACCTCCCGGCTATGTTGGCTATGAAGAAGGCGGAGAGCTGACTGAAAAAGTTC
GCAACAAGCCTTATTCGGTCCTCCTTTTTGACGAGGTGGAAAAAGCCCATCCGGATATTTTTAATGTTTTGCTGCAGGTT
CTTGACGATGGCATGCTGACAGATAGCCGCGGCCGTCAGGTCGATTTTTCCAATACCATTATCATTATGACCAGCAACTT
AGGAGCAACTGCCTTGCGTGATGACAAAACTGTCGGATTTGGTGCCAAGTCTGTCAGTCAGGACTATCAAGCAATGCAGA
GCCGGATTTTGGAAGAGCTCAAACATGCCTACCGCCCTGAATTTTTGAATCGTATTGATGAAACAGTGGTCTTCCACAGC
CTGAGTCAGGATGACATGCGGCAAATTGTTAAGATTATGGTAGCACCGCTCATCCGCAATCTGGCAGAAAAAGGAATTAC
TCTTAAATTCCAGCCTTCTGCCTTGAAGTATCTGGCGCAGGATGGCTATGATAGTGAAATGGGAGCCCGGCCTCTGCGCA
GAGCGCTGCAGACCCAAGTTGAAGACAGGCTGTCTGAGTTAGTGCTCTCAGGCGAGCTAACCAGCGGCAGGACTGTTAAA
ATCGGCCTCTCTAAGGGGAAATTAGCATTTGCTCTTGCTTGA

Domains

Predicted by InterproScan.

AAA domain (Cdc48 subfamily) (AAA_2)

(543-714)

Clp amino terminal domain, pathogenicity island component (Clp_N)

(19-55)

Clp amino terminal domain, pathogenicity island component (Clp_N)

(103-136)

AAA lid domain (AAA_lid_9)

(374-451)

ATPase family associated with various cellular activities (AAA) (AAA)

(235-368)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(721-801)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A172Q9G3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Streptococcus mutans UA159

79.877

99.631

0.796
  clpC Streptococcus thermophilus LMG 18311

71.166

100

0.713
  clpC Streptococcus thermophilus LMD-9

70.798

100

0.71
  clpC Streptococcus pneumoniae TIGR4

66.994

100

0.672
  clpC Streptococcus pneumoniae Rx1

66.83

100

0.669
  clpC Streptococcus pneumoniae D39

66.83

100

0.669
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

50.365

100

0.509
  clpC Bacillus subtilis subsp. subtilis str. 168

43.062

100

0.443
  clpE Streptococcus mutans UA159

48.13

75.646

0.364

Multiple sequence alignment