Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   BSG24_RS11015 Genome accession   NZ_CP018121
Coordinates   2099903..2100559 (-) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain MRSN346355     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2094903..2105559
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BSG24_RS10980 (BSG24_10360) - 2095791..2096093 (-) 303 Protein_2003 transposase -
  BSG24_RS10985 (BSG24_10365) - 2096119..2096771 (+) 653 Protein_2004 hypothetical protein -
  BSG24_RS11005 (BSG24_10385) pgsA 2097469..2098017 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  BSG24_RS11010 (BSG24_10390) uvrC 2098074..2099906 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  BSG24_RS11015 (BSG24_10395) letA 2099903..2100559 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  BSG24_RS29425 - 2100701..2100772 (+) 72 Protein_2008 transcriptional regulator -
  BSG24_RS28155 (BSG24_10400) yecU 2100855..2101031 (+) 177 WP_000590347.1 protein YecU -
  BSG24_RS11020 (BSG24_10405) yecF 2101018..2101242 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  BSG24_RS11025 (BSG24_10410) sdiA 2101310..2102032 (-) 723 WP_001154260.1 transcriptional regulator SdiA -
  BSG24_RS11030 (BSG24_10415) tcyN 2102262..2103014 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  BSG24_RS11035 (BSG24_10420) tcyL 2103011..2103679 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  BSG24_RS11040 (BSG24_10425) dcyD 2103694..2104680 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=172680 BSG24_RS11015 WP_000611328.1 2099903..2100559(-) (letA) [Escherichia coli strain MRSN346355]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=172680 BSG24_RS11015 WP_000611328.1 2099903..2100559(-) (letA) [Escherichia coli strain MRSN346355]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGCCTTGAGGCAACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACTGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGAGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCTGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CATTAAGCCAGATCGAACCAGAAAAAACAGAAAGTCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACTAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482