Detailed information NTG0170705

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: AYM13_RS10785
• Genome accession: NZ_CP014362
• Coordinates: 2058775..2059818 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain USA300-SUR1
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2053775..2064818

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AYM13_RS10755 (AYM13_10485)	-	2054193..2055449 (-)	1257	WP_001795438.1	aminopeptidase	-
AYM13_RS10760 (AYM13_10490)	-	2055452..2055652 (-)	201	WP_000180461.1	DUF1128 family protein	-
AYM13_RS10765 (AYM13_10495)	-	2055799..2056263 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
AYM13_RS10770 (AYM13_10500)	-	2056270..2056545 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
AYM13_RS10775 (AYM13_10505)	-	2056823..2058040 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
AYM13_RS10780 (AYM13_10510)	vraR	2058156..2058785 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
AYM13_RS10785 (AYM13_10515)	vraS	2058775..2059818 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
AYM13_RS10790 (AYM13_10520)	liaF	2059815..2060516 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
AYM13_RS10795 (AYM13_10525)	-	2060531..2060917 (-)	387	WP_001110179.1	hypothetical protein	-
AYM13_RS10800 (AYM13_10530)	map	2061134..2061892 (-)	759	WP_050901419.1	type I methionyl aminopeptidase	-
AYM13_RS10815 (AYM13_10540)	-	2062420..2063406 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
AYM13_RS10825 (AYM13_10545)	-	2063896..2064309 (-)	414	WP_001549145.1	hypothetical protein	-
AYM13_RS10830 (AYM13_10550)	-	2064338..2064448 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=170705 AYM13_RS10785 WP_001017131.1 2058775..2059818(-) (vraS) [Staphylococcus aureus strain USA300-SUR1]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=170705 AYM13_RS10785 WP_001017131.1 2058775..2059818(-) (vraS) [Staphylococcus aureus strain USA300-SUR1]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTTTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1