Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   AXE83_RS02970 Genome accession   NZ_CP014264
Coordinates   618383..619072 (+) Length   229 a.a.
NCBI ID   WP_060955366.1    Uniprot ID   A0A0X8JXB8
Organism   Streptococcus sp. oral taxon 431 strain F0610 (5-114)     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 613383..624072
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AXE83_RS02945 (AXE83_02945) gpsB 613426..613755 (+) 330 WP_000146538.1 cell division regulator GpsB -
  AXE83_RS02955 (AXE83_02955) - 614237..615394 (+) 1158 WP_049527389.1 class I SAM-dependent RNA methyltransferase -
  AXE83_RS02960 (AXE83_02960) - 615407..616870 (+) 1464 WP_060955365.1 cell division site-positioning protein MapZ family protein -
  AXE83_RS02965 (AXE83_02965) gndA 616947..618371 (+) 1425 WP_003017375.1 NADP-dependent phosphogluconate dehydrogenase -
  AXE83_RS02970 (AXE83_02970) covR 618383..619072 (+) 690 WP_060955366.1 response regulator transcription factor Regulator
  AXE83_RS02975 (AXE83_02975) - 619302..620219 (+) 918 WP_060955367.1 N-acetylmuramoyl-L-alanine amidase family protein -
  AXE83_RS02980 (AXE83_02980) mvk 620343..621221 (+) 879 WP_060955368.1 mevalonate kinase -
  AXE83_RS02985 (AXE83_02985) mvaD 621203..622156 (+) 954 WP_060955369.1 diphosphomevalonate decarboxylase -
  AXE83_RS02990 (AXE83_02990) - 622143..623156 (+) 1014 WP_060955370.1 phosphomevalonate kinase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26751.84 Da        Isoelectric Point: 7.0638

>NTDB_id=169989 AXE83_RS02970 WP_060955366.1 618383..619072(+) (covR) [Streptococcus sp. oral taxon 431 strain F0610 (5-114)]
MGKRILLLEKERNLAHFLSLELQKEQYRVDQVEEGQKALSMALQTDYDLILLNAHLGDMTAQDFADKLSRTKPAAVIMVL
DHREELQDQLETIQRFAVSYIYKPIIIDDLVSRISAIFRGRDFIDQHCSQMKVPTAYRNLRMDVEHHTVYRGDEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKIDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=169989 AXE83_RS02970 WP_060955366.1 618383..619072(+) (covR) [Streptococcus sp. oral taxon 431 strain F0610 (5-114)]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAAAGAAATCTAGCTCATTTTTTAAGTCTGGAACTCCAAAAAGAGCAATA
CCGAGTTGATCAGGTAGAAGAGGGACAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGACTTGATTTTACTGAATG
CTCATCTAGGGGATATGACAGCCCAGGATTTTGCAGATAAGTTGAGTCGAACCAAGCCAGCTGCGGTGATCATGGTCTTG
GACCATCGAGAAGAATTGCAAGACCAACTTGAAACAATCCAGCGTTTCGCTGTTTCATACATATATAAACCTATTATTAT
TGATGATTTGGTCAGTCGCATTTCAGCTATCTTCCGAGGTCGAGATTTCATCGACCAACACTGTAGTCAGATGAAAGTTC
CGACAGCTTATCGTAATCTGCGTATGGATGTTGAACACCATACAGTCTATCGTGGCGATGAAATGATTGCTCTCACTCGT
CGTGAATATGACCTCTTAGCTACACTCATGGGCAGTAAGAAAGTCTTAACTCGTGAACAATTGCTAGAGAGCGTCTGGAA
GTATGAAAGTGCTACAGAGACCAATATCGTAGATGTCTATATCCGATATCTACGGAGCAAGATTGATGTCAAAGGTCAAA
AGAGCTACATCAAAACAGTGCGTGGTGTTGGTTATACCATGCAGGAATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0X8JXB8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

49.13

100

0.493
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.053

99.563

0.459

Multiple sequence alignment