Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   AXF35_RS13470 Genome accession   NZ_CP014255
Coordinates   2983232..2983891 (-) Length   219 a.a.
NCBI ID   WP_011216518.1    Uniprot ID   -
Organism   Legionella pneumophila subsp. pascullei strain F-4185     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2978232..2988891
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AXF35_RS13455 (AXF35_03480) - 2979513..2980172 (+) 660 WP_027222794.1 hypothetical protein -
  AXF35_RS13460 (AXF35_03475) lcl 2980219..2981340 (+) 1122 WP_061773165.1 collagen-like adhesin Lcl -
  AXF35_RS13465 (AXF35_03470) uvrC 2981364..2983220 (-) 1857 WP_027222795.1 excinuclease ABC subunit UvrC -
  AXF35_RS13470 (AXF35_03465) letA 2983232..2983891 (-) 660 WP_011216518.1 two-component system response regulator LetA Regulator
  AXF35_RS13475 (AXF35_03460) phhA 2984016..2984834 (-) 819 Protein_2612 phenylalanine 4-monooxygenase -
  AXF35_RS13480 (AXF35_03455) - 2985272..2986369 (+) 1098 WP_027222797.1 competence/damage-inducible protein A -
  AXF35_RS13485 (AXF35_03450) cgtA 2986328..2987353 (-) 1026 WP_027222798.1 Obg family GTPase CgtA -
  AXF35_RS13490 (AXF35_03445) rpmA 2987572..2987850 (-) 279 WP_010948350.1 50S ribosomal protein L27 -
  AXF35_RS13495 (AXF35_03440) rplU 2987863..2988174 (-) 312 WP_010948351.1 50S ribosomal protein L21 -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24556.49 Da        Isoelectric Point: 5.1572

>NTDB_id=169840 AXF35_RS13470 WP_011216518.1 2983232..2983891(-) (letA) [Legionella pneumophila subsp. pascullei strain F-4185]
MIKVLIVDDHALVRMGIRRLLEDMSDVDVVADAESGEQALAYVKTHSPDVVLLDMKMPGIDGWEVTRRLKKTNPNIKVIA
VTAICSDPLPTRVLQLGAMGYLTKESGAEEMAAAIRKVAKGEKYLSAEIAQKMAINSLQESQDSPFDLLSEREMQVMLMI
TSGMNVQDIADRLFLSSKTINGYRYRMFEKLGIKNDVELTYLAMKHRIIEHPNDLSQDD

Nucleotide


Download         Length: 660 bp        

>NTDB_id=169840 AXF35_RS13470 WP_011216518.1 2983232..2983891(-) (letA) [Legionella pneumophila subsp. pascullei strain F-4185]
TTGATTAAAGTATTAATTGTTGATGACCATGCATTGGTTAGAATGGGCATTCGACGATTGCTTGAAGATATGTCGGATGT
TGATGTTGTTGCAGATGCTGAAAGCGGTGAGCAGGCTTTAGCTTATGTGAAAACCCACTCCCCTGATGTTGTATTATTAG
ACATGAAAATGCCTGGGATAGATGGGTGGGAAGTGACACGTCGTTTAAAAAAAACAAACCCAAATATTAAAGTCATAGCC
GTTACAGCCATTTGCTCAGACCCTCTTCCCACTCGAGTATTGCAATTAGGTGCTATGGGATATCTTACTAAAGAATCCGG
GGCTGAGGAAATGGCCGCTGCAATTCGTAAAGTGGCTAAAGGTGAGAAATATCTTAGTGCCGAGATTGCACAAAAGATGG
CAATTAATAGCCTCCAGGAGTCTCAGGATTCCCCCTTTGATTTATTGTCTGAAAGAGAAATGCAAGTCATGTTGATGATC
ACAAGCGGCATGAATGTACAAGACATTGCTGATAGATTATTTTTAAGTAGTAAAACTATCAATGGTTATCGATACAGGAT
GTTTGAAAAATTGGGAATTAAAAATGATGTGGAGCTTACTTATTTGGCTATGAAGCACCGCATTATTGAGCACCCCAATG
ATTTATCACAAGATGATTAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-116)

Bacterial regulatory proteins, luxR family (GerE)

(148-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

99.543

100

0.995
  letA Legionella pneumophila strain ERS1305867

99.543

100

0.995

Multiple sequence alignment