Detailed information NTG0168696

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: AUP74_RS07160
• Genome accession: NZ_CP014143
• Coordinates: 1633788..1635197 (-)
• Length: 469 a.a.
• NCBI ID: WP_069946979.1
• Uniprot ID: A0A1C9W6W2
• Organism: Microbulbifer aggregans strain CCB-MM1
• Function: regulate pilin expression (predicted from homology) Competence regulation

Genomic Context

Location: 1628788..1640197

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AUP74_RS07140 (AUP74_01442)	-	1628957..1629493 (+)	537	WP_069946975.1	pilus assembly PilX family protein	-
AUP74_RS07145 (AUP74_01443)	-	1629503..1632553 (+)	3051	WP_069946976.1	PilC/PilY family type IV pilus protein	-
AUP74_RS07150 (AUP74_01444)	-	1632631..1633089 (+)	459	WP_069946977.1	type IV pilin protein	-
AUP74_RS07155 (AUP74_01445)	-	1633086..1633682 (-)	597	WP_069946978.1	GspH/FimT family pseudopilin	-
AUP74_RS07160 (AUP74_01446)	pilR	1633788..1635197 (-)	1410	WP_069946979.1	sigma-54-dependent transcriptional regulator	Regulator
AUP74_RS07165 (AUP74_01447)	-	1635278..1636876 (-)	1599	WP_069946980.1	two-component system sensor histidine kinase NtrB	-
AUP74_RS07170 (AUP74_01448)	-	1636976..1638604 (+)	1629	WP_069948750.1	NAD+ synthase	-
AUP74_RS07175 (AUP74_01449)	-	1638671..1639603 (-)	933	WP_145924338.1	outer membrane protein assembly factor BamD	-

Sequence

Protein

• Length: 469 a.a.
• Molecular weight: 52047.36 Da
• Isoelectric Point: 6.0422

>NTDB_id=168696 AUP74_RS07160 WP_069946979.1 1633788..1635197(-) (pilR) [Microbulbifer aggregans strain CCB-MM1]
MQPLALVVDDEPDICELLTLTLQRMDVRCHTAATLEQARRLLAEHRYHFCLTDMRLPDGDGLELVERIQRDLDGQLPIAV
ITAHGNTDTAINALKLGAFDFVSKPVDLERLRGLVQLALRLNRERDDQSATSAPRLLLGEAPAMRKLRAQIAKVARSDAP
IYISGESGSGKELAARSIHLQGPRAEQPFVAVNCGAIPTELMESEFFGHKKGSFTGAHRDKPGLFQSAAGGTLFLDEVAD
LPLPMQVKLLRTIQEKAVRPIGAGQEVPVDVRILCATHKDLSQEVIEGRFRNDLYYRINVIEIQVPALRERAGDIPLLAD
TILRRIARAAGSPPPELAPAALGALQRYRFPGNVRQLENILERAFTLCDEGLIREEDLNLEQDAGPSSAVNPVSRSPRAE
AIADSHEQYRGQFETGHYGSLDEFLESIERQTIESTLQETRWNRTAAAQKLGISFRSLRYRLKKLGLED

Nucleotide

• Length: 1410 bp

>NTDB_id=168696 AUP74_RS07160 WP_069946979.1 1633788..1635197(-) (pilR) [Microbulbifer aggregans strain CCB-MM1]
ATGCAACCACTGGCACTGGTCGTCGACGACGAGCCGGATATCTGTGAGCTCCTGACGCTGACCCTGCAGCGGATGGATGT
GCGCTGCCATACCGCCGCCACCCTGGAGCAGGCCCGCCGCTTGCTGGCGGAGCACCGCTACCACTTCTGCCTCACCGACA
TGCGCCTGCCCGACGGGGATGGCCTGGAGCTCGTTGAACGGATCCAGCGAGATCTGGACGGCCAGCTGCCAATTGCAGTC
ATCACCGCCCACGGCAATACCGATACCGCCATCAACGCCCTGAAGTTGGGCGCCTTCGACTTTGTCAGCAAGCCGGTGGA
CCTGGAGCGACTCCGCGGCCTCGTACAATTGGCATTGCGACTCAACCGTGAGCGCGACGACCAGAGCGCCACTTCCGCTC
CTCGTCTTCTGCTGGGCGAGGCGCCTGCGATGCGCAAACTGCGCGCGCAGATTGCCAAGGTGGCCCGTAGTGACGCACCG
ATTTATATCAGTGGCGAGTCCGGCTCCGGCAAAGAGCTGGCAGCGCGCTCCATTCACCTGCAGGGTCCCCGGGCCGAGCA
ACCATTCGTGGCCGTCAACTGTGGGGCGATTCCCACTGAGCTGATGGAGAGTGAATTCTTCGGCCACAAGAAAGGCAGCT
TTACTGGCGCCCACCGGGACAAGCCGGGCCTGTTCCAGAGCGCCGCCGGCGGTACGCTGTTTCTGGATGAAGTTGCAGAC
CTGCCGCTGCCGATGCAGGTCAAACTGCTGCGAACCATCCAGGAGAAAGCGGTGCGTCCCATTGGCGCGGGCCAGGAGGT
TCCGGTGGACGTGCGGATTCTGTGCGCCACCCATAAAGACCTGTCACAGGAAGTCATCGAGGGACGGTTCCGCAACGACC
TCTACTACCGTATCAACGTCATCGAGATTCAGGTACCCGCACTGCGGGAACGCGCCGGCGATATCCCACTGCTGGCGGAC
ACCATCCTGCGACGCATCGCTCGCGCCGCAGGCTCGCCTCCACCAGAGTTGGCCCCCGCCGCTCTCGGCGCATTGCAGCG
CTACCGCTTCCCCGGCAATGTGCGCCAGCTGGAAAACATTCTCGAACGGGCCTTCACCCTGTGTGACGAGGGCCTCATTC
GCGAGGAGGACCTGAACCTGGAGCAGGATGCCGGCCCCTCTTCCGCAGTCAACCCCGTCAGCCGCTCCCCTCGGGCCGAG
GCAATCGCTGACTCCCATGAGCAGTACCGGGGCCAGTTTGAAACCGGCCACTACGGTTCACTGGATGAGTTCCTGGAGAG
CATTGAACGGCAGACGATCGAAAGTACGCTGCAGGAAACCCGCTGGAACCGCACTGCTGCCGCGCAGAAGCTGGGTATCA
GTTTTCGGTCGCTGCGCTACCGACTAAAGAAGCTTGGCCTCGAAGATTAA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (6-114)

• Bacterial regulatory protein, Fis family (HTH_8) (424-465)

• Sigma-54 interaction domain (Sigma54_activat) (138-304)

3D structure

• AlphaFold DB: A0A1C9W6W2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	61.373	99.36	0.61
pilR	Acinetobacter baumannii strain A118	48.093	100	0.484