Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   AV541_RS09690 Genome accession   NZ_CP014141
Coordinates   1773836..1774840 (+) Length   334 a.a.
NCBI ID   WP_060384769.1    Uniprot ID   -
Organism   Thermus parvatiensis strain RL     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1752673..1792603 1773836..1774840 within 0


Gene organization within MGE regions


Location: 1752673..1792603
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AV541_RS13200 (AV541_09515) - 1752673..1753791 (-) 1119 WP_008630994.1 tyrosine-type recombinase/integrase -
  AV541_RS09515 (AV541_09520) - 1753888..1754862 (-) 975 WP_008630993.1 restriction endonuclease -
  AV541_RS09520 (AV541_09525) - 1754859..1755455 (-) 597 WP_008630991.1 S24 family peptidase -
  AV541_RS13615 (AV541_09530) - 1755637..1755840 (+) 204 WP_008630989.1 helix-turn-helix domain-containing protein -
  AV541_RS11615 - 1755837..1756013 (+) 177 WP_167345971.1 hypothetical protein -
  AV541_RS09530 (AV541_09535) - 1756139..1756351 (+) 213 WP_244363338.1 helix-turn-helix domain-containing protein -
  AV541_RS11480 - 1756348..1756791 (+) 444 WP_008630977.1 hypothetical protein -
  AV541_RS09540 (AV541_09545) - 1756788..1757039 (+) 252 WP_008630975.1 hypothetical protein -
  AV541_RS09545 (AV541_09550) - 1757036..1758262 (+) 1227 WP_008630973.1 hypothetical protein -
  AV541_RS09550 (AV541_09555) - 1758252..1758611 (+) 360 WP_038034990.1 hypothetical protein -
  AV541_RS09555 (AV541_09560) - 1758616..1759602 (+) 987 WP_244880535.1 phosphoadenosine phosphosulfate reductase family protein -
  AV541_RS09560 (AV541_09565) - 1759685..1759966 (+) 282 WP_038034987.1 hypothetical protein -
  AV541_RS11705 (AV541_09570) - 1760068..1760628 (+) 561 WP_060384766.1 hypothetical protein -
  AV541_RS11485 (AV541_09575) - 1760675..1761076 (+) 402 WP_008630963.1 hypothetical protein -
  AV541_RS11710 (AV541_09580) - 1761141..1761509 (+) 369 WP_008630961.1 hypothetical protein -
  AV541_RS09580 (AV541_09585) - 1761487..1762020 (+) 534 WP_008630959.1 N-acetylmuramoyl-L-alanine amidase family protein -
  AV541_RS11490 - 1762008..1762160 (+) 153 WP_156423376.1 hypothetical protein -
  AV541_RS09585 (AV541_09590) - 1762160..1762348 (+) 189 WP_008630955.1 hypothetical protein -
  AV541_RS09590 (AV541_09595) - 1762349..1763029 (+) 681 WP_008630953.1 AAA family ATPase -
  AV541_RS09595 (AV541_09600) - 1763197..1763580 (+) 384 WP_238529934.1 hypothetical protein -
  AV541_RS09600 (AV541_09605) - 1763592..1764107 (+) 516 WP_008630950.1 hypothetical protein -
  AV541_RS09605 (AV541_09610) - 1764116..1764991 (+) 876 WP_008630948.1 hypothetical protein -
  AV541_RS09610 (AV541_09615) - 1765003..1765398 (+) 396 WP_008630946.1 hypothetical protein -
  AV541_RS09615 (AV541_09620) - 1765401..1765655 (+) 255 WP_038035056.1 hypothetical protein -
  AV541_RS11715 - 1765985..1766302 (+) 318 WP_008630943.1 hypothetical protein -
  AV541_RS09625 (AV541_09630) - 1766302..1766526 (+) 225 WP_008630941.1 hypothetical protein -
  AV541_RS09630 (AV541_09635) - 1766516..1766818 (+) 303 WP_038034985.1 hypothetical protein -
  AV541_RS09640 (AV541_09645) - 1767057..1767485 (+) 429 WP_038035049.1 hypothetical protein -
  AV541_RS13205 - 1767482..1767607 (+) 126 WP_269146127.1 hypothetical protein -
  AV541_RS09645 (AV541_09650) - 1767775..1768227 (+) 453 WP_008630936.1 hypothetical protein -
  AV541_RS09650 (AV541_09655) - 1768296..1769396 (+) 1101 WP_008630935.1 hypothetical protein -
  AV541_RS09655 (AV541_09660) - 1769406..1770512 (+) 1107 WP_008630934.1 hypothetical protein -
  AV541_RS09665 (AV541_09670) - 1770912..1771460 (+) 549 WP_008630932.1 transglycosylase SLT domain-containing protein -
  AV541_RS09670 (AV541_09675) - 1771457..1771729 (+) 273 WP_008630931.1 hypothetical protein -
  AV541_RS09680 (AV541_09685) - 1771914..1772801 (-) 888 WP_060384768.1 acyltransferase -
  AV541_RS09685 (AV541_09690) era 1772846..1773751 (-) 906 WP_008630929.1 GTPase Era -
  AV541_RS09690 (AV541_09695) dprA 1773836..1774840 (+) 1005 WP_060384769.1 DNA-processing protein DprA Machinery gene
  AV541_RS09695 (AV541_09700) - 1774844..1775752 (-) 909 WP_008630926.1 manganese catalase family protein -
  AV541_RS09700 (AV541_09705) - 1775862..1776814 (+) 953 Protein_1949 LysR substrate-binding domain-containing protein -
  AV541_RS09705 (AV541_09710) - 1776801..1777757 (+) 957 WP_060384770.1 branched-chain amino acid transaminase -
  AV541_RS09710 (AV541_09715) - 1777747..1777935 (+) 189 WP_038034982.1 hypothetical protein -
  AV541_RS09715 (AV541_09720) - 1777937..1778176 (+) 240 WP_008630920.1 hypothetical protein -
  AV541_RS09720 (AV541_09725) trmH 1778166..1778750 (-) 585 WP_060384771.1 tRNA (guanosine(18)-2'-O)-methyltransferase TrmH -
  AV541_RS09725 (AV541_09730) hisG 1778747..1779367 (-) 621 WP_060384772.1 ATP phosphoribosyltransferase -
  AV541_RS09730 (AV541_09735) - 1779364..1780448 (-) 1085 Protein_1955 ATP phosphoribosyltransferase regulatory subunit -
  AV541_RS09735 (AV541_09740) dcd 1780452..1780997 (-) 546 WP_008630912.1 dCTP deaminase -
  AV541_RS09740 (AV541_09745) - 1781028..1781907 (+) 880 Protein_1957 putative Ig domain-containing protein -
  AV541_RS09745 (AV541_09750) aac(6') 1781904..1782338 (+) 435 WP_008630909.1 aminoglycoside 6'-N-acetyltransferase -
  AV541_RS09750 (AV541_09755) - 1782335..1782814 (-) 480 WP_060384773.1 macro domain-containing protein -
  AV541_RS09755 (AV541_09760) - 1782844..1783551 (+) 708 WP_011174216.1 SDR family NAD(P)-dependent oxidoreductase -
  AV541_RS09760 (AV541_09765) nrdR 1783548..1784009 (+) 462 WP_011174215.1 transcriptional regulator NrdR -
  AV541_RS09770 (AV541_09775) - 1785779..1786186 (+) 408 WP_060384850.1 NUDIX hydrolase -
  AV541_RS09775 (AV541_09780) meaB 1786139..1787085 (-) 947 Protein_1963 methylmalonyl Co-A mutase-associated GTPase MeaB -
  AV541_RS09780 (AV541_09785) - 1787131..1787505 (-) 375 WP_060384774.1 RidA family protein -
  AV541_RS09785 (AV541_09790) - 1787510..1789329 (-) 1820 Protein_1965 PQQ-binding-like beta-propeller repeat protein -
  AV541_RS09790 (AV541_09795) - 1789331..1789567 (-) 237 WP_060384775.1 hypothetical protein -
  AV541_RS09795 (AV541_09800) murA 1789685..1790962 (+) 1278 WP_082709703.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  AV541_RS09800 (AV541_09805) - 1790984..1791427 (-) 444 WP_060384777.1 hypothetical protein -
  AV541_RS09805 (AV541_09810) prfB 1791509..1792603 (+) 1095 WP_060384778.1 peptide chain release factor 2 -

Sequence

Protein


Download         Length: 334 a.a.        Molecular weight: 36261.12 Da        Isoelectric Point: 6.8892

>NTDB_id=168682 AV541_RS09690 WP_060384769.1 1773836..1774840(+) (dprA) [Thermus parvatiensis strain RL]
MDPLALALLPGIGPKRLLEVLKAEDPLGFLRERFPEAWRHLPEAEAQAERERRRAEALGVRLLGLWEEGFPEGLRALPQP
PTHLYLKGELPPEREAVALVGTRRASPWALAFARRLARELSEAGLWVVSGLARGIDREAHLGALEAGGRTLGVLGSALDR
VYPPENRPLAQRMDLLSEFPFGTGPKPEFFPRRNRLIAGLCRAVVVVEAPLDSGALITARHALELGKEVLAVPGRPTDER
SLGANRLIQDGAYPVLSAEDVLSYLGMSARPKPLPGLSPEEEALYALLQEKKEALPEALAMALGIPPERVLSLLTLLELK
GLARALPGGRYGPG

Nucleotide


Download         Length: 1005 bp        

>NTDB_id=168682 AV541_RS09690 WP_060384769.1 1773836..1774840(+) (dprA) [Thermus parvatiensis strain RL]
GTGGACCCCTTGGCCCTCGCCCTCCTCCCGGGCATCGGCCCCAAGCGGCTTTTGGAGGTCCTAAAGGCGGAGGACCCTCT
GGGCTTCCTGCGGGAGCGCTTCCCCGAGGCCTGGCGGCACCTCCCCGAGGCCGAGGCCCAGGCGGAAAGGGAGAGGCGGC
GCGCCGAGGCCCTAGGGGTGCGCCTCCTGGGTCTCTGGGAGGAGGGCTTCCCCGAGGGGCTGAGGGCGCTTCCCCAGCCG
CCCACCCACCTCTACCTGAAGGGGGAGCTTCCCCCGGAAAGGGAGGCGGTGGCCCTCGTGGGCACGCGCCGGGCCTCCCC
TTGGGCCCTGGCCTTTGCCCGGAGGCTCGCCCGGGAGCTTTCCGAGGCCGGGCTTTGGGTGGTCTCGGGCCTCGCCCGGG
GTATAGACCGGGAGGCCCACCTCGGGGCCCTCGAGGCCGGGGGGCGCACCCTGGGCGTCTTGGGAAGCGCCCTGGACCGG
GTCTACCCCCCGGAAAACCGCCCTTTGGCCCAACGGATGGACCTCCTCTCCGAGTTCCCCTTCGGGACCGGCCCTAAGCC
CGAGTTCTTTCCCCGGCGGAACCGCCTCATCGCCGGGCTTTGCCGGGCGGTGGTCGTGGTGGAGGCCCCTCTGGACTCCG
GGGCCCTCATCACCGCCCGCCACGCCCTGGAGCTCGGCAAGGAGGTGCTGGCCGTGCCCGGAAGGCCCACGGACGAGCGC
TCCCTGGGGGCGAACCGCCTCATCCAGGACGGGGCCTACCCGGTGCTCTCCGCCGAGGACGTCCTCTCCTACCTGGGAAT
GTCCGCAAGGCCCAAGCCCCTCCCGGGCCTCTCCCCGGAGGAGGAGGCCCTTTACGCCCTCCTGCAGGAAAAGAAGGAGG
CGCTCCCCGAGGCCCTGGCCATGGCCCTGGGGATCCCCCCGGAGCGGGTGCTCTCCCTCCTCACCCTCTTGGAGCTCAAG
GGCCTGGCCCGGGCCCTCCCGGGAGGGCGCTACGGGCCAGGCTAA

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(56-255)

DprA winged helix domain (DprA_WH)

(269-329)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Thermus thermophilus HB27

99.102

100

0.991
  dprA Vibrio campbellii strain DS40M4

38.268

100

0.41
  dprA Deinococcus radiodurans R1 = ATCC 13939 = DSM 20539

45.392

87.725

0.398
  dprA Vibrio cholerae strain A1552

36.975

100

0.395

Multiple sequence alignment