Detailed information NTG0168222

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: AL519_RS01275
• Genome accession: NZ_CP014064
• Coordinates: 173173..174159 (+)
• Length: 328 a.a.
• NCBI ID: WP_000959282.1
• Uniprot ID: A0A7U7EXT8
• Organism: Staphylococcus aureus strain FDAARGOS_159
• Function: require for natural transformation (predicted from homology) Unclear

Genomic Context

Location: 168173..179159

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AL519_RS01250 (AL519_01240)	opp4B	168387..169349 (+)	963	WP_000915997.1	oligopeptide ABC transporter permease	-
AL519_RS01255 (AL519_01245)	opp4C	169361..170242 (+)	882	WP_001180280.1	oligopeptide ABC transporter permease	-
AL519_RS01260 (AL519_01250)	trpS	170284..171273 (-)	990	WP_000448934.1	tryptophan--tRNA ligase	-
AL519_RS01265 (AL519_01255)	spxA	171567..171962 (+)	396	WP_000258003.1	transcriptional regulator SpxA	-
AL519_RS01270 (AL519_01260)	mecA	172333..173052 (+)	720	WP_001217728.1	adaptor protein MecA	-
AL519_RS01275 (AL519_01265)	coiA	173173..174159 (+)	987	WP_000959282.1	competence protein CoiA	Machinery gene
AL519_RS01280 (AL519_01270)	pepF	174207..176015 (+)	1809	WP_000082725.1	oligoendopeptidase F	-
AL519_RS01285 (AL519_01275)	yjbH	176475..177281 (-)	807	WP_000896697.1	protease adaptor protein YjbH	-
AL519_RS01290 (AL519_01280)	-	177304..177669 (-)	366	WP_000214070.1	truncated hemoglobin YjbI	-
AL519_RS01295 (AL519_01285)	-	177773..178366 (-)	594	WP_000224619.1	CYTH domain-containing protein	-
AL519_RS01300 (AL519_01290)	-	178552..178899 (+)	348	WP_001242103.1	hypothetical protein	-

Sequence

Protein

• Length: 328 a.a.
• Molecular weight: 38878.55 Da
• Isoelectric Point: 9.5714

>NTDB_id=168222 AL519_RS01275 WP_000959282.1 173173..174159(+) (coiA) [Staphylococcus aureus strain FDAARGOS_159]
MLVALNEEKERVLATTALRKTQYFCPVCGKQVILKRGLKVISHFAHKHLAEQKCFNNETIKHYKSKLILAQMIQQQGCKV
EIEPFLKEIKQIPDILINNKYVIELQYSPIPYKQILQRTEGLKKMGYKVSWLLNDVDYCHNKVKFNHFHSLFINPITRKL
HTFNLEKKQIMMFQQIQYLGGHKYVAEKRNAKIIELFNEAPCDYHAVYKLSKFAINQYIKYCRWQNSVLEPTLSAMYQLQ
LTDQEVVYNYGYIFPEQIYIENHPIEWQLQVDLWLKNGKSKLVNDNLNYFKLKKFIVALESKTAIIEKLINNYLNICSDR
GNDVQILF

Nucleotide

• Length: 987 bp

>NTDB_id=168222 AL519_RS01275 WP_000959282.1 173173..174159(+) (coiA) [Staphylococcus aureus strain FDAARGOS_159]
ATGTTAGTAGCTTTAAATGAAGAAAAGGAACGTGTGTTAGCAACTACTGCATTGAGAAAGACACAATATTTTTGTCCTGT
GTGTGGCAAGCAAGTTATTTTAAAGCGTGGGCTCAAAGTAATTAGTCATTTTGCACATAAACATTTAGCGGAACAAAAAT
GTTTTAATAATGAAACGATTAAACATTATAAAAGTAAATTGATTTTAGCACAGATGATACAGCAACAAGGATGTAAAGTA
GAGATAGAGCCATTTTTAAAAGAAATAAAACAAATTCCGGATATTTTGATTAATAATAAATATGTTATTGAGCTACAGTA
TTCGCCAATTCCTTATAAACAGATTCTTCAACGAACGGAAGGTTTAAAGAAAATGGGATATAAAGTAAGTTGGTTATTAA
ATGATGTTGATTATTGTCATAATAAAGTGAAGTTCAATCATTTTCATAGTTTGTTTATTAATCCAATCACTCGAAAACTT
CATACGTTCAATTTAGAGAAAAAACAAATAATGATGTTTCAACAAATACAATATTTAGGCGGGCACAAATATGTCGCTGA
AAAAAGGAATGCCAAAATTATTGAGTTGTTTAATGAGGCGCCTTGTGATTATCATGCTGTTTATAAATTATCAAAGTTCG
CAATTAATCAATATATCAAATATTGTCGCTGGCAAAATTCTGTTTTAGAACCCACTTTAAGTGCAATGTATCAATTACAG
TTAACTGATCAAGAAGTAGTGTACAATTATGGTTATATTTTTCCAGAGCAAATTTATATTGAAAATCATCCAATTGAGTG
GCAATTACAAGTTGATTTATGGTTAAAGAATGGAAAAAGCAAATTAGTAAATGACAATCTTAATTATTTTAAACTGAAAA
AATTTATTGTTGCTCTAGAAAGTAAAACAGCAATTATAGAAAAACTTATTAACAATTATTTAAATATTTGTTCAGATAGA
GGTAATGACGTGCAAATTTTGTTCTAA

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (6-308)

3D structure

• AlphaFold DB: A0A7U7EXT8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Staphylococcus aureus N315	100	100	1
coiA	Staphylococcus aureus MW2	97.561	100	0.976