Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexA   Type   Machinery gene
Locus tag   A4W88_RS01760 Genome accession   NZ_CP017275
Coordinates   365270..367873 (+) Length   867 a.a.
NCBI ID   WP_076631954.1    Uniprot ID   -
Organism   Latilactobacillus sakei strain TMW 1.1398     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 360270..372873
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A4W88_RS01750 (A4W88_01735) - 362436..364265 (+) 1830 WP_076631952.1 APC family permease -
  A4W88_RS01755 (A4W88_01740) - 364442..365248 (+) 807 WP_076631953.1 TIGR00282 family metallophosphoesterase -
  A4W88_RS01760 (A4W88_01745) hexA 365270..367873 (+) 2604 WP_076631954.1 DNA mismatch repair protein MutS Machinery gene
  A4W88_RS01765 (A4W88_01750) hexB 367897..369855 (+) 1959 WP_076631955.1 DNA mismatch repair endonuclease MutL Machinery gene
  A4W88_RS01770 (A4W88_01755) - 369855..370400 (+) 546 WP_011374073.1 Maf family protein -
  A4W88_RS01775 (A4W88_01760) - 370413..370976 (+) 564 WP_011374074.1 TIGR00730 family Rossman fold protein -
  A4W88_RS01780 (A4W88_01765) ruvA 371387..371998 (+) 612 WP_011374075.1 Holliday junction branch migration protein RuvA Machinery gene

Sequence

Protein


Download         Length: 867 a.a.        Molecular weight: 96690.50 Da        Isoelectric Point: 5.3879

>NTDB_id=167774 A4W88_RS01760 WP_076631954.1 365270..367873(+) (hexA) [Latilactobacillus sakei strain TMW 1.1398]
MPQKTKETPMMAQYQKVKDQYPDAFLFYRLGDFYELFNDDAVKASQLLELTLTARNKNAADPIPMCGVPHHAAQNYIDIL
VDQGYKVAICEQMEDPKTAKGMVKREVVQLVTPGTVMDEKAGHAKQNNYLTAVVAQGDQFGFAYTDLSTGEMKVSQISSL
DVLLNEMLSLQTKEVVVNHDVPSEVVQAFVQQQILVSYQGEGADTAEVSFVSQNISQPLALAVIKQLVVYLATTQKRHLG
HLQRAQAYEPSQYLKLDHSAKMNLELTASLRTGHKSGTLLWLLDETKTAMGGRLLKQWLERPLLDLNQIKNRQNQVASFL
QHYFERTNLQEALTKVYDLERLAGRVAFGSVNGRDLIQLKTSLEQIPKIKDVLTGINETQAFDQALTRLDPVDDVRTLIE
TAINPDSPISVTDGGIIQDGYDEQLDQYRNAMSNGKQWLAQLEAQEREATGIHNLKIGFNRVFGYYIEVTRANLSSLPEG
RYERKQTLTNAERFITPELKEKEQLILEAEERSTALEYELFTQVREQVKLQIERLQTLAKGVAALDVLQSFAVVSESYHY
VQPTLRTDSREIDLVDGRHPVVEKVLGRQKYIPNAVQMGKETDMLLITGPNMSGKSTYMRQLALTVIMAQMGCFVPAKSA
NLPVFDQIFTRIGAADDLISGQSTFMVEMMEANRAIMSATANSLILFDEIGRGTATYDGMALAQAIIEYIHDHVHAKTLF
STHYHELTALADTLTALRNVHVGAVEENGELVFLHKMLAGPADKSYGIHVAKLAGMPETLLQRADVILGQLEDKPKAPVQ
PATVAPAQPAAAAVEEQMALFEPEVAAPVDKKTDKVVAAIKNFDLMSATPLEALNQLYEWQKQLNKH

Nucleotide


Download         Length: 2604 bp        

>NTDB_id=167774 A4W88_RS01760 WP_076631954.1 365270..367873(+) (hexA) [Latilactobacillus sakei strain TMW 1.1398]
ATGCCGCAAAAAACAAAAGAAACGCCAATGATGGCCCAATATCAAAAGGTTAAGGATCAATATCCAGACGCCTTTTTATT
TTATAGATTGGGTGATTTTTACGAATTATTCAATGACGATGCTGTTAAAGCATCACAACTTTTAGAATTAACGCTGACAG
CGCGTAATAAGAATGCAGCAGACCCCATTCCGATGTGTGGTGTGCCCCATCATGCAGCGCAAAACTACATTGATATTTTA
GTGGATCAAGGTTACAAGGTCGCCATTTGCGAACAGATGGAAGATCCTAAAACGGCTAAGGGCATGGTCAAACGCGAAGT
TGTCCAATTAGTAACACCTGGGACTGTGATGGACGAAAAAGCCGGTCACGCTAAACAAAATAATTATTTAACGGCAGTCG
TTGCACAAGGCGATCAATTTGGCTTTGCCTATACAGATTTATCCACAGGTGAAATGAAGGTTAGCCAAATCAGTAGTTTA
GATGTGTTATTAAACGAAATGTTGAGTTTACAAACCAAAGAAGTGGTTGTGAATCATGATGTCCCAAGTGAAGTCGTCCA
AGCCTTTGTCCAACAACAAATCTTGGTTTCTTATCAAGGTGAGGGGGCCGATACGGCAGAGGTCAGTTTTGTTTCTCAAA
ACATCTCACAACCACTAGCGTTAGCCGTCATTAAACAATTAGTTGTTTATTTAGCAACGACGCAAAAGCGGCACTTGGGT
CATTTACAACGCGCCCAAGCCTATGAACCTTCTCAATACTTGAAGTTGGATCATTCAGCTAAGATGAACCTCGAATTAAC
GGCTTCATTACGAACTGGTCATAAGAGTGGGACGTTATTGTGGTTATTGGATGAAACGAAGACTGCGATGGGTGGTCGTT
TATTAAAACAATGGTTGGAACGACCATTGTTGGATCTAAACCAGATTAAGAACCGGCAAAACCAAGTCGCTAGTTTCTTA
CAGCATTATTTTGAACGGACGAACCTTCAAGAAGCCCTAACCAAAGTTTATGATTTGGAACGTCTAGCAGGCCGCGTTGC
TTTTGGGAGCGTTAATGGTCGCGATTTGATTCAATTAAAAACATCCTTAGAACAGATTCCAAAGATTAAAGATGTTTTGA
CGGGCATTAACGAAACGCAGGCTTTTGATCAAGCGTTAACGCGTTTAGATCCAGTTGATGATGTGCGGACGTTAATTGAG
ACAGCGATTAACCCGGATTCACCGATTTCAGTGACTGATGGTGGGATTATTCAAGATGGTTACGACGAACAACTTGATCA
ATACCGCAATGCGATGTCTAACGGCAAGCAGTGGTTGGCGCAATTAGAGGCGCAAGAACGAGAAGCCACGGGCATTCATA
ATTTGAAAATCGGCTTTAACCGCGTCTTTGGGTATTATATCGAAGTCACGCGTGCTAACTTGAGTTCATTACCGGAAGGG
CGGTATGAACGGAAACAAACGTTAACCAACGCCGAACGATTCATCACACCGGAATTAAAAGAAAAAGAACAACTGATTTT
AGAGGCGGAAGAACGCTCAACCGCTCTAGAATACGAATTATTTACCCAAGTTCGGGAACAAGTGAAGTTACAGATTGAAC
GGCTCCAAACATTGGCTAAAGGCGTAGCGGCTCTAGATGTCCTACAAAGTTTTGCGGTCGTCAGCGAAAGCTACCACTAT
GTCCAACCAACATTAAGAACTGATAGTCGCGAAATTGATTTAGTCGATGGCCGTCATCCTGTGGTTGAGAAGGTATTGGG
ACGGCAAAAATATATCCCGAATGCCGTTCAAATGGGCAAAGAGACGGATATGTTATTAATTACCGGGCCTAATATGTCTG
GTAAAAGTACCTACATGCGGCAATTGGCCTTAACGGTCATCATGGCGCAAATGGGTTGTTTTGTACCTGCCAAGTCAGCG
AACTTGCCTGTATTTGATCAAATCTTTACCCGCATTGGCGCGGCAGATGATTTGATTTCAGGACAAAGTACGTTTATGGT
AGAAATGATGGAAGCTAACCGTGCGATTATGAGTGCGACCGCCAATAGTTTAATTCTCTTCGATGAAATTGGTCGGGGAA
CGGCCACTTATGATGGGATGGCCTTGGCACAAGCGATTATCGAATATATTCATGATCATGTCCACGCTAAGACGCTCTTT
TCAACGCATTATCATGAACTGACGGCTTTAGCCGATACGTTGACCGCCCTTCGTAACGTGCATGTTGGTGCAGTTGAGGA
AAACGGTGAGTTGGTCTTCTTACACAAGATGTTGGCCGGACCTGCGGATAAGTCTTACGGGATTCATGTCGCTAAACTAG
CGGGCATGCCAGAAACCTTATTACAACGGGCCGATGTTATTTTAGGTCAATTAGAAGATAAACCAAAAGCACCGGTGCAA
CCAGCAACAGTCGCGCCAGCACAACCGGCTGCAGCGGCTGTCGAAGAACAGATGGCGCTTTTTGAACCAGAAGTGGCGGC
TCCGGTCGATAAGAAAACAGATAAAGTGGTAGCAGCAATTAAGAATTTTGATTTGATGAGCGCCACACCACTAGAAGCCC
TCAATCAATTATATGAGTGGCAAAAGCAATTAAATAAACATTAA

Domains

Predicted by InterProScan.

MutS domain II (MutS_II)

(128-243)

MutS family domain IV (MutS_IV)

(420-512)

MutS domain I (MutS_I)

(8-119)

MutS domain V (MutS_V)

(605-792)

MutS domain III (MutS_III)

(263-552)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexA Streptococcus pneumoniae R6

52.139

99.769

0.52
  mutS Pseudomonas stutzeri strain ATCC 17587

38.453

100

0.39

Multiple sequence alignment