Detailed information NTG0167485

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: AL510_RS00260
• Genome accession: NZ_CP014027
• Coordinates: 47855..49084 (-)
• Length: 409 a.a.
• NCBI ID: WP_002984948.1
• Uniprot ID: A0A4U7GJW1
• Organism: Streptococcus pyogenes strain FDAARGOS_149
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 42855..54084

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AL510_RS00240 (AL510_00230)	rpiA	43136..43819 (-)	684	WP_010922176.1	ribose-5-phosphate isomerase RpiA	-
AL510_RS00245 (AL510_00235)	-	44198..46297 (+)	2100	WP_010922175.1	AAA family ATPase	-
AL510_RS00250 (AL510_00240)	-	46355..47098 (-)	744	WP_002984942.1	hypothetical protein	-
AL510_RS00255 (AL510_00245)	yihA	47246..47845 (-)	600	WP_002984945.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
AL510_RS00260 (AL510_00250)	clpX	47855..49084 (-)	1230	WP_002984948.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
AL510_RS00265 (AL510_09185)	-	49214..49384 (-)	171	WP_002984950.1	hypothetical protein	-
AL510_RS00270 (AL510_00255)	-	49404..49901 (-)	498	WP_011285487.1	dihydrofolate reductase	-
AL510_RS00275 (AL510_00260)	-	49981..50820 (-)	840	WP_010922172.1	thymidylate synthase	-
AL510_RS00280 (AL510_00265)	-	51029..52204 (+)	1176	WP_010922171.1	hydroxymethylglutaryl-CoA synthase	-
AL510_RS00285 (AL510_00270)	-	52191..53468 (+)	1278	WP_010922170.1	hydroxymethylglutaryl-CoA reductase, degradative	-

Sequence

Protein

• Length: 409 a.a.
• Molecular weight: 44991.44 Da
• Isoelectric Point: 4.5775

>NTDB_id=167485 AL510_RS00260 WP_002984948.1 47855..49084(-) (clpX) [Streptococcus pyogenes strain FDAARGOS_149]
MAGSRTNDIKVYCSFCGKSQDDVKKIIAGNNVFICNECVALSQEIIKEELAEEVLADLTEVPKPKELLDVLNQYVVGQDR
AKRALSVAVYNHYKRVSFTESRDDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTK
NILFIVGGAFDGIEEIVKQRLGEKVIGFGQNSRKIDDNASYMQEIISEDIQKFGLIPEFIGRLPVVAALEQLNTSDLIQI
LTEPRNALVKQYQALLSYDGVELAFDKEALEAIANKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVTKVRITKAAVEG
KSKPVLETA

Nucleotide

• Length: 1230 bp

>NTDB_id=167485 AL510_RS00260 WP_002984948.1 47855..49084(-) (clpX) [Streptococcus pyogenes strain FDAARGOS_149]
ATGGCAGGAAGTAGAACTAACGATATTAAAGTATACTGTTCATTTTGTGGTAAAAGCCAGGATGACGTTAAAAAAATTAT
CGCAGGAAATAATGTTTTCATCTGCAATGAATGCGTAGCTTTATCACAAGAAATTATAAAAGAAGAATTGGCTGAAGAAG
TCCTTGCCGATTTGACAGAAGTTCCAAAACCAAAAGAGCTCCTTGATGTTTTAAATCAATATGTGGTTGGTCAAGATCGT
GCTAAACGTGCTTTATCAGTTGCTGTGTACAATCATTATAAGCGTGTCTCGTTTACAGAAAGTCGTGATGACGATGATGT
GGATTTACAAAAGTCCAACATTTTGATGATTGGACCAACAGGTTCAGGAAAAACCTTCTTAGCACAAACTCTGGCTAAAA
GCCTCAATGTACCATTTGCTATTGCAGATGCAACTTCTTTGACTGAAGCAGGGTATGTTGGAGAAGATGTGGAAAATATT
TTACTCAAACTGATTCAGGCTGCTGACTATAATGTCGAACGAGCAGAGCGTGGTATTATTTATGTTGATGAAATAGATAA
GATTGCTAAAAAAGGTGAGAACGTATCTATCACACGTGATGTATCTGGTGAAGGTGTACAGCAAGCCCTTCTTAAAATTA
TTGAAGGTACGGTAGCAAGTGTTCCCCCACAAGGTGGGCGGAAGCACCCTAATCAAGAAATGATCCAAATTGATACAAAA
AATATCTTGTTTATTGTTGGCGGGGCTTTTGATGGCATCGAGGAGATCGTTAAACAACGTTTAGGTGAAAAAGTTATTGG
TTTTGGTCAAAACAGCCGTAAAATTGATGACAATGCTTCTTATATGCAAGAAATTATTTCAGAAGATATTCAAAAGTTTG
GGCTTATTCCAGAATTTATTGGCCGCTTACCAGTTGTGGCAGCCCTTGAACAACTAAACACATCAGATTTGATTCAAATT
TTGACAGAACCAAGAAATGCCCTGGTCAAGCAATATCAGGCTCTTCTTTCTTACGATGGCGTCGAATTGGCATTTGATAA
GGAAGCCTTAGAAGCCATTGCCAATAAAGCCATTGAACGTAAGACAGGAGCACGTGGTCTTCGTTCTATTATCGAAGAAA
CGATGCTTGACATCATGTTTGAAATTCCAAGCCAAGAAGATGTCACAAAAGTGCGTATCACCAAGGCTGCTGTCGAAGGC
AAGTCAAAACCCGTTTTAGAGACAGCTTAA

Domains

Predicted by InterproScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (110-305)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (312-391)

• ClpX C4-type zinc finger (zf-C4_ClpX) (12-48)

3D structure

• AlphaFold DB: A0A4U7GJW1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	88.998	100	0.89
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.603	98.044	0.575