Detailed information    

insolico Bioinformatically predicted

Overview

Name   comK/comK1   Type   Regulator
Locus tag   AL501_RS00340 Genome accession   NZ_CP014023
Coordinates   75279..75848 (+) Length   189 a.a.
NCBI ID   WP_002459481.1    Uniprot ID   -
Organism   Staphylococcus lugdunensis strain FDAARGOS_143     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 76330..83339 75279..75848 flank 482


Gene organization within MGE regions


Location: 75279..83339
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AL501_RS00340 (AL501_00340) comK/comK1 75279..75848 (+) 570 WP_002459481.1 competence protein ComK Regulator
  AL501_RS00355 (AL501_00355) - 76330..76803 (-) 474 WP_080693586.1 tyrosine-type recombinase/integrase -
  AL501_RS00360 (AL501_00360) - 76908..77552 (-) 645 WP_037544584.1 hypothetical protein -
  AL501_RS12850 - 77569..78156 (-) 588 WP_230580268.1 hypothetical protein -
  AL501_RS12855 - 78361..78591 (-) 231 WP_237450151.1 ImmA/IrrE family metallo-endopeptidase -
  AL501_RS00375 (AL501_00375) - 78647..78973 (-) 327 WP_062077454.1 helix-turn-helix domain-containing protein -
  AL501_RS12965 - 79651..79905 (+) 255 WP_335682235.1 hypothetical protein -
  AL501_RS12970 - 79927..80103 (+) 177 WP_230580322.1 YolD-like family protein -
  AL501_RS00395 (AL501_00390) - 80557..80892 (-) 336 WP_037546031.1 hypothetical protein -
  AL501_RS00400 (AL501_00395) - 80898..82091 (-) 1194 WP_062077459.1 hypothetical protein -
  AL501_RS00405 (AL501_00400) - 82118..82519 (+) 402 WP_062077461.1 DUF1433 domain-containing protein -
  AL501_RS00410 (AL501_00405) - 82915..83100 (-) 186 WP_002459476.1 hypothetical protein -
  AL501_RS12860 - 83238..83339 (-) 102 WP_237450153.1 SAR1012 family small protein -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 22480.96 Da        Isoelectric Point: 9.8301

>NTDB_id=167397 AL501_RS00340 WP_002459481.1 75279..75848(+) (comK/comK1) [Staphylococcus lugdunensis strain FDAARGOS_143]
MDKKTIYVIRKGDMVIRPIIDDYGHAQGTEIIKFDTTKERSPFKTQKIIERSCKFYGNNYLSKKAETSRIARINSKPPIL
LTPLFPTYFFPTHSDRQEENIWINMHFIVDIKPLKHRKSKVIFANHETLIINVSFHSMWHQYINAIFYYYMVDKQSKMRS
NNPDMPIDYEKSSLNIYEALSQYSLLDNK

Nucleotide


Download         Length: 570 bp        

>NTDB_id=167397 AL501_RS00340 WP_002459481.1 75279..75848(+) (comK/comK1) [Staphylococcus lugdunensis strain FDAARGOS_143]
ATGGACAAAAAAACCATATATGTTATACGTAAAGGAGATATGGTCATACGACCCATTATCGACGATTATGGACATGCTCA
AGGAACAGAAATCATTAAATTTGACACCACAAAAGAAAGAAGCCCATTTAAAACGCAGAAAATTATAGAAAGATCTTGCA
AGTTTTACGGAAATAATTATCTTAGCAAAAAAGCAGAAACAAGTCGAATCGCTCGTATTAATAGCAAACCTCCGATATTA
CTCACTCCCTTATTCCCAACTTATTTTTTTCCAACACATTCTGACAGACAAGAAGAAAACATATGGATTAATATGCATTT
TATTGTAGATATTAAGCCTTTAAAGCACAGAAAAAGTAAAGTCATTTTTGCTAATCATGAAACACTTATCATAAATGTGT
CATTTCATAGTATGTGGCATCAATATATAAATGCCATTTTTTATTACTACATGGTAGATAAACAGTCTAAAATGCGTTCA
AATAACCCCGATATGCCTATTGATTATGAAAAATCCTCACTAAATATTTACGAAGCACTTTCCCAATATTCTCTATTAGA
TAATAAATAG

Domains

Predicted by InterproScan.

ComK protein (ComK)

(5-156)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comK/comK1 Staphylococcus aureus MW2

69.312

100

0.693
  comK/comK1 Staphylococcus aureus N315

69.312

100

0.693

Multiple sequence alignment