Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   BFP66_RS02060 Genome accession   NZ_CP017142
Coordinates   392491..393132 (+) Length   213 a.a.
NCBI ID   WP_002937025.1    Uniprot ID   A0A0H3MTV8
Organism   Streptococcus suis strain GZ0565     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 387491..398132
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BFP66_RS02040 (BFP66_02040) - 387791..388528 (+) 738 WP_004194145.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  BFP66_RS02045 (BFP66_02045) pknB 388528..390057 (+) 1530 Protein_361 Stk1 family PASTA domain-containing Ser/Thr kinase -
  BFP66_RS11355 - 390058..390522 (+) 465 Protein_362 PASTA domain-containing protein -
  BFP66_RS02050 (BFP66_02050) liaF 390847..391506 (+) 660 WP_223375661.1 cell wall-active antibiotics response protein LiaF -
  BFP66_RS02055 (BFP66_02055) - 391503..392519 (+) 1017 WP_024395772.1 sensor histidine kinase -
  BFP66_RS02060 (BFP66_02060) vraR 392491..393132 (+) 642 WP_002937025.1 response regulator transcription factor Regulator
  BFP66_RS02065 (BFP66_02065) - 393182..394582 (+) 1401 WP_014637530.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  BFP66_RS02070 (BFP66_02070) - 394584..394955 (+) 372 WP_002937017.1 S1 RNA-binding domain-containing protein -
  BFP66_RS02075 (BFP66_02075) cysK 394981..395907 (-) 927 WP_015646509.1 cysteine synthase A -
  BFP66_RS02080 (BFP66_02080) - 395997..396629 (-) 633 WP_024389592.1 YigZ family protein -
  BFP66_RS02085 (BFP66_02085) comFA/cflA 396686..397978 (+) 1293 WP_024395771.1 DEAD/DEAH box helicase Machinery gene

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23790.36 Da        Isoelectric Point: 4.8970

>NTDB_id=166777 BFP66_RS02060 WP_002937025.1 392491..393132(+) (vraR) [Streptococcus suis strain GZ0565]
MNTIRVMLVDDHEMVRLGLKSYLNLQPDVEVVAEASDGEEGLAKALEVKPDVVVMDLVMPKMTGVEATLALLKEWPQAQI
VILTSYLDNEKIYPVLEAGARGYMLKTSSADEILAAIRKVALGEYAIETEVEKKVEHHKRHPDLHDDLTAREREILTLLA
KGYDNQRIADESFISLKTVKTHVSNILSKLAVSDRTQAVVYAFQHGLVAQEDQ

Nucleotide


Download         Length: 642 bp        

>NTDB_id=166777 BFP66_RS02060 WP_002937025.1 392491..393132(+) (vraR) [Streptococcus suis strain GZ0565]
ATGAATACGATTCGAGTGATGTTGGTTGACGACCATGAGATGGTTCGTCTAGGATTGAAAAGTTACTTAAATTTACAGCC
AGATGTTGAAGTAGTTGCAGAAGCTAGTGATGGCGAGGAAGGTTTGGCTAAAGCATTAGAGGTTAAACCCGATGTTGTAG
TGATGGACTTGGTTATGCCCAAGATGACTGGCGTAGAAGCAACCTTGGCCTTGCTGAAGGAATGGCCGCAAGCGCAGATT
GTCATCCTGACCTCCTATCTAGATAATGAAAAAATCTATCCTGTGCTGGAAGCAGGAGCTCGTGGCTATATGTTGAAAAC
GTCAAGTGCTGACGAAATCTTAGCAGCCATCCGCAAGGTAGCTCTTGGAGAATATGCTATTGAGACAGAAGTAGAGAAAA
AAGTAGAGCACCATAAACGCCACCCAGATTTACATGATGACTTGACAGCTCGTGAACGCGAAATCTTGACGCTGTTAGCC
AAGGGATATGATAATCAACGAATTGCAGATGAGTCCTTCATATCCTTAAAAACTGTTAAGACCCATGTTTCCAATATCTT
ATCCAAACTAGCTGTTAGCGATCGTACTCAAGCAGTTGTTTATGCTTTCCAGCATGGTTTGGTGGCGCAAGAGGACCAAT
AG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(148-202)

Response regulator receiver domain (Response_reg)

(6-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H3MTV8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

54.589

97.183

0.531
  degU Bacillus subtilis subsp. subtilis str. 168

38.938

100

0.413