Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   ASL15_RS08765 Genome accession   NZ_CP013955
Coordinates   1768283..1768969 (-) Length   228 a.a.
NCBI ID   WP_001802022.1    Uniprot ID   A0A7U7EYP5
Organism   Staphylococcus aureus strain NCCP14562 isolate Sequencing     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1763283..1773969
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ASL15_RS08745 (ASL15_08750) - 1764186..1764725 (-) 540 Protein_1697 ComEC/Rec2 family competence protein -
  ASL15_RS08750 (ASL15_08755) - 1764824..1765996 (+) 1173 WP_000195429.1 IS256-like element IS256 family transposase -
  ASL15_RS08755 (ASL15_08760) - 1765986..1767725 (-) 1740 Protein_1699 ComEC/Rec2 family competence protein -
  ASL15_RS08760 (ASL15_08765) - 1767730..1768191 (-) 462 WP_000439693.1 ComE operon protein 2 -
  ASL15_RS08765 (ASL15_08770) comEA 1768283..1768969 (-) 687 WP_001802022.1 ComEA family DNA-binding protein Machinery gene
  ASL15_RS08770 (ASL15_08775) - 1769009..1769725 (-) 717 WP_000084830.1 class I SAM-dependent DNA methyltransferase -
  ASL15_RS08775 (ASL15_08780) rsfS 1769728..1770081 (-) 354 WP_001088020.1 ribosome silencing factor -
  ASL15_RS08780 (ASL15_08785) yqeK 1770082..1770666 (-) 585 WP_001019324.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  ASL15_RS08785 (ASL15_08790) nadD 1770656..1771225 (-) 570 WP_000725167.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  ASL15_RS08790 (ASL15_08795) yhbY 1771228..1771518 (-) 291 WP_000955235.1 ribosome assembly RNA-binding protein YhbY -
  ASL15_RS08795 (ASL15_08800) aroE 1771522..1772328 (-) 807 WP_000666757.1 shikimate dehydrogenase -
  ASL15_RS08800 (ASL15_08805) yqeH 1772342..1773442 (-) 1101 WP_001280137.1 ribosome biogenesis GTPase YqeH -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25900.65 Da        Isoelectric Point: 9.6751

>NTDB_id=166620 ASL15_RS08765 WP_001802022.1 1768283..1768969(-) (comEA) [Staphylococcus aureus strain NCCP14562 isolate Sequencing]
MVLLYQFLLRYKDFLTQWKLYIISAVVLIMVLIGFIFWRQDDYTSRNFENKDTALKQSTSENNSLSKLEDVQVKDGDNSK
NKGPVYVDVKGAVKHPNVYKMTSKDRVVDLLDKAQLLDDADVSRINLSEKLTDQKMIFIPHKGQKNVEPQIEVNSVHVKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTI

Nucleotide


Download         Length: 687 bp        

>NTDB_id=166620 ASL15_RS08765 WP_001802022.1 1768283..1768969(-) (comEA) [Staphylococcus aureus strain NCCP14562 isolate Sequencing]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAGTGGAAGTTATATATTATAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAAATTTTGAAAATAAAGATACTG
CTCTGAAACAAAGCACTAGTGAAAATAATAGTTTGTCCAAATTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAAGGTCCTGTATATGTCGATGTAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTGGATGATGCAGATGTAAGTCGAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATACCTCATAAAGGACAAAAGAATGTTGAACCACAAATTGAAGTAAACAGTGTGCACGTAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACCGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTAGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGATATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7EYP5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus N315

100

100

1
  comEA Staphylococcus aureus MW2

97.368

100

0.974

Multiple sequence alignment