Detailed information NTG0166357

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: AVT04_RS09025
• Genome accession: NZ_CP013939
• Coordinates: 1702897..1703778 (+)
• Length: 293 a.a.
• NCBI ID: WP_011226089.1
• Uniprot ID: Q5M441
• Organism: Streptococcus thermophilus strain S9
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1697897..1708778

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AVT04_RS09000 (AVT04_09000)	-	1699397..1699852 (+)	456	WP_041827047.1	DUF4832 domain-containing protein	-
AVT04_RS09005 (AVT04_09005)	galE	1699867..1700880 (+)	1014	WP_011227279.1	UDP-glucose 4-epimerase GalE	-
AVT04_RS09010 (AVT04_09010)	-	1701068..1701304 (+)	237	WP_002946959.1	DUF1146 family protein	-
AVT04_RS09015 (AVT04_09015)	murA	1701374..1702645 (+)	1272	WP_041827046.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
AVT04_RS09020 (AVT04_09020)	-	1702647..1702835 (+)	189	WP_011227277.1	DNA-directed RNA polymerase subunit beta	-
AVT04_RS09025 (AVT04_09025)	endA	1702897..1703778 (+)	882	WP_011226089.1	DNA/RNA non-specific endonuclease	Machinery gene
AVT04_RS09030 (AVT04_09030)	-	1703849..1704499 (-)	651	WP_011226088.1	amino acid ABC transporter permease	-
AVT04_RS09035 (AVT04_09035)	-	1704511..1705209 (-)	699	WP_011226087.1	amino acid ABC transporter permease	-
AVT04_RS09040 (AVT04_09040)	-	1705227..1706060 (-)	834	WP_011227276.1	transporter substrate-binding domain-containing protein	-
AVT04_RS09045 (AVT04_09045)	-	1706072..1706839 (-)	768	WP_011227275.1	amino acid ABC transporter ATP-binding protein	-
AVT04_RS09050 (AVT04_09050)	vicR	1707371..1708078 (+)	708	WP_011227274.1	response regulator YycF	Regulator

Sequence

Protein

• Length: 293 a.a.
• Molecular weight: 31757.50 Da
• Isoelectric Point: 10.1789

>NTDB_id=166357 AVT04_RS09025 WP_011226089.1 1702897..1703778(+) (endA) [Streptococcus thermophilus strain S9]
MAKRKTSLTNKQKRQLVTLIIAALIAVLGYLGTSNKLSPDNPIRQVASLVAGKSNKSIKSNGSTNSQSTPQEQLAETVMT
SSVKSQLGNSLEWNGAGAYIINRNKTNLNAKVSSQPYANNQVKTVQGQTVPTVANALLSKATRQYKNRQETGNGSTSWTP
AGWHQVQNLSGEYSHAVDRGHLLGYALIGGLKGFDASTSNPENIAVQTAWANQAYSDSSTGQNYYESLVRKALDKNKRVR
YRVTLIYEGENLIPSGTHLEAKSADGSLEFNVFVPNVQEGITLDYYSGKVTVN

Nucleotide

• Length: 882 bp

>NTDB_id=166357 AVT04_RS09025 WP_011226089.1 1702897..1703778(+) (endA) [Streptococcus thermophilus strain S9]
ATGGCAAAAAGAAAGACATCTTTGACAAATAAACAGAAACGTCAGTTAGTCACATTAATAATAGCAGCTTTGATAGCTGT
TTTAGGTTACCTAGGAACCAGTAACAAGCTCTCGCCTGATAATCCTATCAGACAAGTAGCAAGCCTAGTTGCAGGGAAAT
CTAACAAATCCATTAAATCTAATGGTTCAACAAATAGTCAGTCTACACCACAAGAGCAGCTTGCTGAGACAGTAATGACT
AGTTCAGTCAAAAGCCAACTGGGTAATTCCTTGGAATGGAATGGAGCTGGGGCCTACATTATTAATAGAAATAAGACGAA
TCTAAATGCTAAGGTATCAAGCCAACCCTATGCTAATAACCAAGTCAAAACGGTTCAAGGACAAACTGTTCCTACAGTTG
CTAATGCCTTATTAAGTAAAGCAACTAGACAGTACAAAAATCGTCAAGAAACAGGGAATGGTTCAACCTCTTGGACACCA
GCTGGATGGCACCAGGTTCAAAATTTATCAGGAGAGTATAGCCATGCCGTAGATAGAGGCCATTTGCTAGGTTATGCACT
GATAGGTGGTTTGAAAGGATTTGATGCCTCGACTTCAAATCCAGAGAATATTGCTGTTCAAACTGCTTGGGCAAATCAAG
CATATAGCGATAGTTCTACAGGCCAAAACTATTATGAAAGCCTAGTACGAAAAGCCCTGGATAAAAACAAACGTGTTCGT
TATCGTGTGACCCTGATTTATGAAGGAGAGAATCTCATTCCATCAGGAACACATCTTGAAGCTAAGTCAGCAGACGGCTC
ACTTGAGTTTAATGTCTTTGTTCCAAATGTACAAGAGGGAATTACACTAGATTACTATTCAGGAAAAGTAACGGTGAATT
GA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (101-266)

3D structure

• AlphaFold DB: Q5M441

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	72.803	81.57	0.594
endA	Streptococcus pneumoniae D39	72.803	81.57	0.594
endA	Streptococcus pneumoniae R6	72.803	81.57	0.594
endA	Streptococcus pneumoniae TIGR4	72.803	81.57	0.594