Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   A7J08_RS02410 Genome accession   NZ_CP017088
Coordinates   466729..467370 (+) Length   213 a.a.
NCBI ID   WP_079394183.1    Uniprot ID   -
Organism   Streptococcus suis strain SRD478     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 461729..472370
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A7J08_RS02390 (A7J08_02300) - 461897..462634 (+) 738 WP_053866720.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  A7J08_RS02395 (A7J08_02305) stkP 462634..464628 (+) 1995 WP_053866719.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  A7J08_RS02400 (A7J08_02310) liaF 465085..465744 (+) 660 WP_223375661.1 cell wall-active antibiotics response protein LiaF -
  A7J08_RS02405 (A7J08_02315) - 465741..466757 (+) 1017 WP_002937028.1 sensor histidine kinase -
  A7J08_RS02410 (A7J08_02320) vraR 466729..467370 (+) 642 WP_079394183.1 response regulator transcription factor Regulator
  A7J08_RS02415 (A7J08_02325) - 467420..468820 (+) 1401 WP_053867074.1 Cof-type HAD-IIB family hydrolase -
  A7J08_RS02420 (A7J08_02330) - 468822..469193 (+) 372 WP_024394815.1 S1 RNA-binding domain-containing protein -
  A7J08_RS02425 (A7J08_02335) cysK 469220..470146 (-) 927 WP_053867075.1 cysteine synthase A -
  A7J08_RS02430 (A7J08_02340) - 470235..470867 (-) 633 WP_053867076.1 YigZ family protein -
  A7J08_RS02435 (A7J08_02345) comFA/cflA 470924..472216 (+) 1293 WP_053867077.1 DEAD/DEAH box helicase Machinery gene

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23776.33 Da        Isoelectric Point: 4.8970

>NTDB_id=166001 A7J08_RS02410 WP_079394183.1 466729..467370(+) (vraR) [Streptococcus suis strain SRD478]
MNTIRVMLVDDHEMVRLGLKSYLNLQPDVEVVAEASDGEEGLAKALEVKPDVVVMDLVMPKMTGVEATLGLLKEWPQAQI
VILTSYLDNEKIYPVLEAGARGYMLKTSSADEILAAIRKVALGEYAIETEVEKKVEHHKRHPDLHDDLTAREREILTLLA
KGYDNQRIADESFISLKTVKTHVSNILSKLAVSDRTQAVVYAFQHGLVAQEDQ

Nucleotide


Download         Length: 642 bp        

>NTDB_id=166001 A7J08_RS02410 WP_079394183.1 466729..467370(+) (vraR) [Streptococcus suis strain SRD478]
ATGAATACGATTCGAGTGATGCTGGTTGACGACCATGAGATGGTTCGTCTAGGATTGAAAAGTTACTTAAATTTACAGCC
AGATGTTGAAGTAGTTGCAGAAGCTAGTGATGGCGAGGAAGGTTTAGCTAAAGCATTAGAGGTTAAACCCGATGTTGTAG
TGATGGACTTGGTTATGCCTAAGATGACTGGCGTAGAAGCAACCCTGGGCTTGCTGAAGGAATGGCCGCAAGCGCAGATT
GTCATCCTGACCTCCTACCTAGATAATGAGAAAATCTATCCTGTGCTGGAAGCAGGAGCTCGTGGCTATATGTTGAAAAC
GTCAAGTGCTGACGAAATCTTAGCAGCCATCCGCAAGGTAGCTCTTGGAGAATATGCTATTGAGACAGAAGTAGAGAAAA
AAGTAGAGCACCATAAACGCCACCCAGATTTACATGATGACTTGACAGCTCGTGAACGCGAAATCTTGACGCTGTTAGCC
AAGGGATATGATAATCAACGAATTGCAGATGAGTCCTTCATATCCTTAAAAACTGTTAAGACCCATGTTTCCAATATCTT
ATCCAAACTAGCTGTTAGCGATCGTACTCAAGCAGTTGTTTATGCTTTCCAGCATGGTTTGGTGGCGCAAGAGGACCAAT
AG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(6-118)

Bacterial regulatory proteins, luxR family (GerE)

(148-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

54.589

97.183

0.531
  degU Bacillus subtilis subsp. subtilis str. 168

38.938

100

0.413