Detailed information NTG0165430

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: BC350_RS11840
• Genome accession: NZ_CP016914
• Coordinates: 2462700..2464988 (+)
• Length: 762 a.a.
• NCBI ID: WP_011002381.1
• Uniprot ID: Q8XWL0
• Organism: Ralstonia pseudosolanacearum strain CQPS-1
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 2457700..2469988

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BC350_RS11815 (BC350_11480)	-	2459137..2459775 (+)	639	WP_019718360.1	IS1595 family transposase	-
BC350_RS11820 (BC350_11485)	-	2459949..2460161 (+)	213	WP_011002385.1	hypothetical protein	-
BC350_RS11825 (BC350_11490)	-	2460350..2460970 (-)	621	WP_011002384.1	DUF4126 domain-containing protein	-
BC350_RS11830 (BC350_11495)	-	2461620..2461823 (-)	204	WP_011002383.1	cold-shock protein	-
BC350_RS11835 (BC350_11500)	clpS	2462377..2462703 (+)	327	WP_011002382.1	ATP-dependent Clp protease adapter ClpS	-
BC350_RS11840 (BC350_11505)	clpC	2462700..2464988 (+)	2289	WP_011002381.1	ATP-dependent Clp protease ATP-binding subunit ClpA	Regulator
BC350_RS11845 (BC350_11510)	dut	2465058..2465504 (-)	447	WP_011002380.1	dUTP diphosphatase	-
BC350_RS11850 (BC350_11515)	-	2465501..2466553 (-)	1053	WP_011002379.1	LLM class flavin-dependent oxidoreductase	-
BC350_RS11855 (BC350_11520)	coaBC	2466550..2467755 (-)	1206	WP_011002378.1	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC	-
BC350_RS11860 (BC350_11525)	-	2467904..2468479 (+)	576	WP_058907805.1	YdcF family protein	-
BC350_RS11865 (BC350_11530)	lspA	2468519..2469040 (-)	522	WP_011002376.1	signal peptidase II	-

Sequence

Protein

• Length: 762 a.a.
• Molecular weight: 83548.71 Da
• Isoelectric Point: 6.2902

>NTDB_id=165430 BC350_RS11840 WP_011002381.1 2462700..2464988(+) (clpC) [Ralstonia pseudosolanacearum strain CQPS-1]
MIAQELEVSLHMAFVEARQARHEFITVEHLLLALLDNPTAAEVLRACAANIEDLRTHLKNFIADNTPVVPGTDEVDTQPT
LGFQRVIQRAIMHVQSTSNGKKEVTGANVLVAIFGEKDSHAVYYLQQQGVTRLDVVNFISHGIRKDQAEPAKHGDSNPEG
EAGDGKESPLEQFTQNLNALAKAGKIDPLIGREQEVERVVQVLCRRRKNNPLLVGEAGVGKTAIAEGLAWRITKGEVPDI
LARSVVYSLDMGALLAGTKYRGDFEQRLKGVLKSLKDNPNAILFIDEIHTLIGAGAASGGTLDASNLLKPALSSGALKCI
GATTFTEYRGIFEKDAALSRRFQKIDVVEPSIDQTVQILRGLKSRFEEHHGVKYAASALTAAAELSARFITDRHLPDKAI
DVIDEAGAAQRILPKSKQKKTIGKGEIEDIVSRIARVPPQSVSQDDRSKLQTLERDLKSVVFGQDPAIDALASAIKMSRA
GLGKTDKPIGSFLFSGPTGVGKTEVAKQLAFILGIELIRFDMSEYMERHAVSRLIGAPPGYVGFDQGGLLTEAITKKPHC
VLLLDEIEKAHPDIFNILLQVMDHGSLTDNNGRKADFRNVIIVMTTNAGAETMNKATIGFTTTREQGDEMADIKRMFTPE
FRNRLDATISFRSLDEDIILRVVDKFLMQLEEQLHEKKVDAVFTEKLRRFLAKKGFDPLMGARPMQRLIQDMIRKALADE
LLFGKLVNGGKVAVDLDDADAVKLEFSENEAPPAPAQEEAEA

Nucleotide

• Length: 2289 bp

>NTDB_id=165430 BC350_RS11840 WP_011002381.1 2462700..2464988(+) (clpC) [Ralstonia pseudosolanacearum strain CQPS-1]
ATGATCGCGCAAGAACTGGAAGTCAGCCTGCACATGGCGTTTGTCGAAGCCCGCCAGGCTCGCCACGAATTCATTACGGT
GGAGCATCTGCTGCTTGCGCTGCTGGACAATCCGACGGCGGCGGAAGTGCTGCGCGCCTGCGCCGCCAACATCGAAGACC
TCCGCACGCACCTGAAGAACTTCATCGCCGACAACACGCCGGTGGTGCCGGGCACGGACGAGGTGGACACGCAGCCGACG
CTGGGCTTCCAGCGCGTGATCCAGCGCGCCATCATGCACGTGCAGTCGACCTCCAACGGCAAGAAGGAGGTGACGGGCGC
CAATGTGCTGGTGGCCATCTTCGGCGAGAAGGACTCCCACGCGGTCTACTACCTGCAGCAGCAGGGCGTGACGCGGCTGG
ACGTCGTCAACTTCATCAGCCACGGCATCCGCAAGGACCAGGCCGAGCCGGCCAAGCACGGCGACAGCAACCCGGAGGGC
GAAGCCGGCGACGGCAAGGAAAGCCCGCTGGAGCAGTTCACCCAGAACCTGAACGCGCTGGCCAAGGCCGGCAAGATCGA
TCCGCTGATCGGCCGCGAGCAGGAAGTCGAGCGCGTGGTGCAGGTGCTGTGCCGTCGCCGCAAGAACAATCCGCTGCTGG
TGGGCGAGGCGGGCGTCGGCAAGACGGCGATCGCCGAAGGGCTGGCATGGCGCATCACCAAGGGCGAGGTGCCGGACATC
CTGGCCCGGTCTGTGGTGTATTCGCTCGACATGGGCGCGCTGCTGGCCGGCACCAAGTATCGTGGCGACTTCGAGCAGCG
GCTCAAGGGCGTGCTGAAGTCGCTCAAGGACAACCCGAACGCGATCCTGTTCATCGACGAAATCCATACGCTGATCGGCG
CCGGCGCCGCATCGGGCGGCACGCTGGACGCGAGCAACCTGCTCAAGCCGGCGCTGTCGTCGGGCGCGCTCAAGTGCATC
GGCGCGACCACCTTCACCGAATACCGGGGCATCTTCGAGAAGGACGCGGCGCTGTCGCGGCGCTTCCAGAAGATCGACGT
GGTGGAGCCGTCCATTGACCAGACCGTGCAGATCCTGCGTGGGCTGAAGTCGCGGTTCGAGGAGCACCACGGCGTCAAGT
ACGCGGCGTCCGCCCTGACGGCGGCGGCTGAGCTGTCGGCGCGCTTCATTACTGACCGCCACCTGCCGGACAAGGCGATC
GACGTGATCGACGAGGCCGGCGCGGCGCAGCGCATCCTGCCGAAGTCGAAGCAGAAGAAGACCATCGGCAAGGGCGAGAT
TGAAGACATCGTGTCGCGCATCGCCCGTGTCCCGCCGCAAAGCGTGTCGCAGGACGACCGCAGCAAGCTGCAGACGCTGG
AGCGCGATCTGAAGTCGGTCGTGTTCGGGCAGGACCCGGCCATCGACGCGCTGGCTTCGGCCATCAAGATGTCGCGTGCC
GGGCTGGGCAAGACCGACAAGCCGATCGGCTCGTTCCTGTTCTCCGGCCCGACCGGCGTCGGCAAGACCGAGGTCGCCAA
GCAGCTGGCGTTCATCCTGGGCATCGAGCTGATCCGCTTCGACATGTCGGAGTACATGGAACGCCATGCGGTGAGCCGGC
TGATCGGCGCGCCTCCGGGCTACGTCGGGTTCGACCAGGGCGGCCTGCTGACCGAGGCCATCACCAAGAAGCCGCACTGC
GTGCTGCTGCTGGACGAAATCGAGAAGGCCCACCCGGACATCTTCAACATCCTGCTGCAAGTGATGGACCACGGCTCGCT
GACGGACAACAACGGCCGCAAGGCGGATTTCCGCAACGTGATCATCGTCATGACGACCAACGCGGGCGCCGAGACGATGA
ACAAGGCCACCATCGGCTTCACCACGACGCGCGAGCAGGGCGACGAGATGGCCGATATCAAGCGGATGTTCACGCCGGAG
TTCCGCAACCGCCTGGATGCGACCATCAGCTTCCGCTCGCTGGACGAGGACATCATCCTGCGCGTGGTCGACAAGTTCCT
GATGCAGCTGGAAGAGCAACTGCACGAGAAGAAGGTGGACGCCGTCTTCACCGAGAAGCTGCGCCGCTTCCTGGCGAAGA
AGGGCTTCGACCCGCTGATGGGCGCGCGGCCGATGCAGCGCCTGATCCAGGACATGATCCGCAAGGCGCTGGCCGACGAG
CTGCTGTTCGGCAAGCTGGTCAACGGCGGCAAGGTGGCGGTGGACCTGGACGATGCCGACGCGGTCAAGCTGGAGTTCTC
CGAGAACGAGGCGCCGCCCGCGCCCGCGCAGGAAGAGGCGGAAGCCTGA

Domains

Predicted by InterProScan.

• ATPase family associated with various cellular activities (AAA) (AAA) (212-324)

• AAA domain (Cdc48 subfamily) (AAA_2) (487-647)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (654-734)

• AAA lid domain (AAA_lid_9) (351-454)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (13-62)

3D structure

• AlphaFold DB: Q8XWL0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	40.718	100	0.432
clpC	Streptococcus thermophilus LMG 18311	38.095	100	0.409
clpA	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	42.582	95.538	0.407
clpC	Streptococcus thermophilus LMD-9	43.614	84.252	0.367