Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   AVR58_RS13670 Genome accession   NZ_CP013742
Coordinates   3004111..3004770 (-) Length   219 a.a.
NCBI ID   WP_011216518.1    Uniprot ID   -
Organism   Legionella pneumophila strain Philadelphia-1 isolate AE     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2999111..3009770
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AVR58_RS13655 (AVR58_13290) - 2999911..3000570 (+) 660 WP_010948343.1 hypothetical protein -
  AVR58_RS13660 (AVR58_13295) lcl 3000738..3002219 (+) 1482 WP_010948344.1 collagen-like adhesin Lcl -
  AVR58_RS13665 (AVR58_13300) uvrC 3002243..3004099 (-) 1857 WP_010948345.1 excinuclease ABC subunit UvrC -
  AVR58_RS13670 (AVR58_13305) letA 3004111..3004770 (-) 660 WP_011216518.1 two-component system response regulator LetA Regulator
  AVR58_RS13675 (AVR58_13310) phhA 3004895..3005713 (-) 819 WP_010948347.1 phenylalanine 4-monooxygenase -
  AVR58_RS13680 (AVR58_13315) - 3006152..3007249 (+) 1098 WP_010948348.1 competence/damage-inducible protein A -
  AVR58_RS13685 (AVR58_13320) cgtA 3007208..3008233 (-) 1026 WP_010948349.1 Obg family GTPase CgtA -
  AVR58_RS13690 (AVR58_13325) rpmA 3008448..3008726 (-) 279 WP_010948350.1 50S ribosomal protein L27 -
  AVR58_RS13695 (AVR58_13330) rplU 3008739..3009050 (-) 312 WP_010948351.1 50S ribosomal protein L21 -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24556.49 Da        Isoelectric Point: 5.1572

>NTDB_id=164630 AVR58_RS13670 WP_011216518.1 3004111..3004770(-) (letA) [Legionella pneumophila strain Philadelphia-1 isolate AE]
MIKVLIVDDHALVRMGIRRLLEDMSDVDVVADAESGEQALAYVKTHSPDVVLLDMKMPGIDGWEVTRRLKKTNPNIKVIA
VTAICSDPLPTRVLQLGAMGYLTKESGAEEMAAAIRKVAKGEKYLSAEIAQKMAINSLQESQDSPFDLLSEREMQVMLMI
TSGMNVQDIADRLFLSSKTINGYRYRMFEKLGIKNDVELTYLAMKHRIIEHPNDLSQDD

Nucleotide


Download         Length: 660 bp        

>NTDB_id=164630 AVR58_RS13670 WP_011216518.1 3004111..3004770(-) (letA) [Legionella pneumophila strain Philadelphia-1 isolate AE]
TTGATTAAAGTATTAATTGTTGATGACCATGCATTGGTTAGAATGGGCATTCGACGATTGCTTGAAGATATGTCGGATGT
TGATGTAGTTGCAGATGCTGAAAGTGGTGAGCAGGCTTTAGCCTATGTAAAAACCCACTCCCCTGATGTCGTATTATTAG
ATATGAAAATGCCTGGGATAGATGGGTGGGAAGTGACGCGTCGTTTAAAAAAAACAAACCCAAATATTAAAGTCATAGCT
GTTACAGCTATTTGCTCAGATCCTCTCCCTACTCGAGTATTGCAATTAGGTGCTATGGGATACCTTACTAAAGAGTCAGG
GGCTGAAGAAATGGCTGCCGCAATTCGTAAAGTGGCTAAAGGTGAGAAATATCTTAGTGCCGAGATAGCACAAAAAATGG
CAATTAATAGTCTTCAGGAGTCTCAGGATTCCCCTTTTGATTTATTGTCTGAAAGAGAAATGCAAGTCATGTTGATGATT
ACTAGCGGCATGAATGTACAAGACATTGCTGATAGATTATTTTTAAGTAGTAAAACCATCAATGGCTATCGATATAGGAT
GTTTGAAAAATTGGGGATTAAAAATGATGTGGAGCTTACTTATTTGGCTATGAAGCACCGCATTATTGAGCACCCCAATG
ATTTGTCACAAGATGATTAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-116)

Bacterial regulatory proteins, luxR family (GerE)

(148-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

99.543

100

0.995
  letA Legionella pneumophila strain ERS1305867

99.543

100

0.995

Multiple sequence alignment