Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   A7U44_RS10620 Genome accession   NZ_CP016856
Coordinates   2090300..2091016 (-) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   P0A0I7
Organism   Staphylococcus aureus strain 2148.N     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2085300..2096016
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A7U44_RS10600 (A7U44_0715) - 2086392..2087342 (+) 951 WP_000790325.1 LacI family DNA-binding transcriptional regulator -
  A7U44_RS10605 (A7U44_0716) - 2087491..2088975 (+) 1485 WP_000141430.1 sucrose-6-phosphate hydrolase -
  A7U44_RS10610 (A7U44_0717) - 2088972..2089931 (+) 960 WP_001253305.1 carbohydrate kinase family protein -
  A7U44_RS10615 (A7U44_04505) - 2090119..2090228 (-) 110 Protein_1996 hypothetical protein -
  A7U44_RS10620 (A7U44_0718) agrA 2090300..2091016 (-) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  A7U44_RS10625 (A7U44_04510) agrC 2091035..2092327 (-) 1293 WP_174672469.1 quorum-sensing sensor histidine kinase AgrC -
  A7U44_RS10630 (A7U44_0721) agrD 2092352..2092492 (-) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  A7U44_RS10635 (A7U44_0722) agrB 2092489..2093058 (-) 570 WP_001105707.1 accessory gene regulator AgrB -
  A7U44_RS14535 hld 2093348..2093428 (+) 81 WP_000046022.1 delta-hemolysin -
  A7U44_RS10645 (A7U44_0724) - 2094028..2094813 (-) 786 WP_000867942.1 carbon-nitrogen family hydrolase -
  A7U44_RS10650 (A7U44_0725) - 2095174..2095800 (-) 627 WP_000522384.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=164292 A7U44_RS10620 WP_000688492.1 2090300..2091016(-) (agrA) [Staphylococcus aureus strain 2148.N]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=164292 A7U44_RS10620 WP_000688492.1 2090300..2091016(-) (agrA) [Staphylococcus aureus strain 2148.N]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGCGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  PDB 3BS1
  PDB 4G4K

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1

Multiple sequence alignment