Detailed information NTG0164057

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: AU077_RS07270
• Genome accession: NZ_CP013688
• Coordinates: 1464362..1465447 (-)
• Length: 361 a.a.
• NCBI ID: WP_014294114.1
• Uniprot ID: A0A380K6B4
• Organism: Streptococcus gallolyticus strain ICDDRB-NRC-S1
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1459362..1470447

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AU077_RS07240 (AU077_07240)	-	1459977..1460555 (-)	579	WP_014294121.1	YutD family protein	-
AU077_RS07245 (AU077_07245)	-	1460587..1461912 (-)	1326	WP_058621857.1	bifunctional metallophosphatase/5'-nucleotidase	-
AU077_RS07250 (AU077_07250)	-	1462025..1462534 (-)	510	WP_014294119.1	hypothetical protein	-
AU077_RS07255 (AU077_07255)	-	1462673..1463342 (-)	670	Protein_1495	MIP/aquaporin family protein	-
AU077_RS07260 (AU077_07260)	-	1463418..1463906 (+)	489	Protein_1496	transposase	-
AU077_RS07265 (AU077_07265)	-	1463979..1464233 (-)	255	WP_014294115.1	DUF3923 family protein	-
AU077_RS07270 (AU077_07270)	sepM	1464362..1465447 (-)	1086	WP_014294114.1	SepM family pheromone-processing serine protease	Regulator
AU077_RS07275 (AU077_07275)	coaD	1465425..1465922 (-)	498	WP_058621858.1	pantetheine-phosphate adenylyltransferase	-
AU077_RS07280 (AU077_07280)	rsmD	1465955..1466494 (-)	540	WP_039670565.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
AU077_RS07285 (AU077_07285)	-	1466627..1467385 (+)	759	Protein_1501	hypothetical protein	-
AU077_RS07290 (AU077_07290)	asnA	1467519..1468511 (-)	993	WP_014294109.1	aspartate--ammonia ligase	-
AU077_RS07295 (AU077_07295)	-	1468884..1470099 (-)	1216	Protein_1503	MFS transporter	-

Sequence

Protein

• Length: 361 a.a.
• Molecular weight: 39123.86 Da
• Isoelectric Point: 4.1372

>NTDB_id=164057 AU077_RS07270 WP_014294114.1 1464362..1465447(-) (sepM) [Streptococcus gallolyticus strain ICDDRB-NRC-S1]
MAILKRFKEILKKLGRILYRFKWWILGVVGIAFLLFSLLYPLDYYIEMPGGVYDIRSVLTVDNKEDDEDGSYNFVAVKVS
QATLAQLVYAWLTPYTEISTAADVTGGYSNADYLRINEYYMETSQNTATYQALTLAGKEATLDYQGVYVLNVSDNSTFKG
ILNIADTVTGVNGQTFNSSAELMAYVADLDLGSEVTVQYTSDGEAKEATGKIIELSNGKNGIGIGLVDHTSVSSDVDVDF
HTSGVGGPSAGLMFTLDIYDQLNGEDLRKGRKIAGTGTIESDGSVGDIGGAALKVVAAAKAGADIFFVPNNPVDEETLKK
DPDAKTNYEEAVEAAKDLDTDMKIVPVTTVQEAIDYLRNND

Nucleotide

• Length: 1086 bp

>NTDB_id=164057 AU077_RS07270 WP_014294114.1 1464362..1465447(-) (sepM) [Streptococcus gallolyticus strain ICDDRB-NRC-S1]
ATGGCAATCTTAAAAAGATTTAAAGAGATTTTGAAAAAGTTGGGTCGTATTTTATATCGCTTTAAGTGGTGGATATTAGG
TGTTGTAGGCATTGCTTTCTTACTATTTAGCTTGTTGTATCCGCTTGATTACTATATTGAAATGCCTGGTGGTGTTTATG
ATATTCGTAGCGTTTTAACAGTTGATAATAAGGAAGATGATGAAGATGGCTCTTATAATTTTGTGGCTGTCAAGGTTAGT
CAGGCGACCTTGGCACAATTGGTTTATGCTTGGTTAACTCCCTACACAGAAATTTCGACAGCCGCAGATGTGACTGGTGG
TTATAGCAATGCTGATTATCTTCGTATCAATGAGTATTACATGGAAACCTCTCAAAATACAGCGACTTATCAAGCCTTAA
CCTTGGCAGGAAAGGAAGCGACGCTTGATTATCAAGGGGTTTATGTTTTAAATGTTAGTGATAATTCGACGTTTAAAGGG
ATTTTGAATATCGCTGATACGGTAACTGGGGTTAATGGTCAGACATTTAACAGTTCGGCAGAATTAATGGCCTATGTGGC
TGATTTGGATTTAGGGTCTGAGGTAACAGTTCAATATACATCAGACGGCGAAGCAAAAGAAGCCACAGGGAAAATTATTG
AATTGTCAAATGGAAAAAATGGTATCGGAATCGGTTTGGTAGATCATACGTCGGTGTCATCAGATGTTGATGTTGATTTT
CATACGAGTGGTGTCGGTGGTCCAAGTGCTGGTTTGATGTTTACGCTTGATATTTATGACCAATTAAATGGTGAAGATTT
GCGTAAAGGTCGTAAAATTGCTGGTACAGGTACGATTGAATCAGATGGTTCAGTCGGGGATATTGGTGGCGCAGCACTCA
AAGTTGTTGCTGCTGCTAAAGCTGGTGCGGATATTTTCTTTGTTCCAAATAACCCTGTGGATGAGGAAACATTGAAAAAA
GATCCTGATGCGAAAACGAACTATGAAGAAGCTGTCGAAGCTGCTAAAGACCTCGATACCGATATGAAAATCGTCCCAGT
CACAACGGTCCAAGAAGCAATTGACTATCTACGAAACAATGATTAA

Domains

Predicted by InterproScan.

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (246-323)

• PDZ domain (PDZ_2) (145-209)

3D structure

• AlphaFold DB: A0A380K6B4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	67.742	94.46	0.64