Detailed information NTG0163386

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: ATM98_RS00450
• Genome accession: NZ_CP013651
• Coordinates: 76809..79076 (-)
• Length: 755 a.a.
• NCBI ID: WP_061563681.1
• Uniprot ID: -
• Organism: Streptococcus sp. A12
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 71809..84076

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ATM98_RS00435 (ATM98_00435)	ileS	72836..75628 (+)	2793	WP_061563678.1	isoleucine--tRNA ligase	-
ATM98_RS00440 (ATM98_00440)	-	75733..76032 (-)	300	WP_061563679.1	DUF1827 family protein	-
ATM98_RS00445 (ATM98_00445)	-	76100..76549 (-)	450	WP_061563680.1	NUDIX hydrolase	-
ATM98_RS00450 (ATM98_00450)	clpE	76809..79076 (-)	2268	WP_061563681.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
ATM98_RS00455 (ATM98_00455)	-	79306..79536 (+)	231	WP_006596773.1	DUF1797 family protein	-
ATM98_RS00460 (ATM98_00460)	-	79693..80547 (+)	855	WP_061563682.1	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase	-
ATM98_RS00465 (ATM98_00465)	-	80680..81534 (+)	855	WP_061563683.1	NAD(P)H-hydrate dehydratase	-
ATM98_RS00470 (ATM98_00470)	xseA	81647..82987 (+)	1341	WP_061563684.1	exodeoxyribonuclease VII large subunit	-
ATM98_RS00475 (ATM98_00475)	-	82965..83177 (+)	213	WP_006596769.1	exodeoxyribonuclease VII small subunit	-
ATM98_RS00480 (ATM98_00480)	-	83174..84061 (+)	888	WP_061563685.1	polyprenyl synthetase family protein	-

Sequence

Protein

• Length: 755 a.a.
• Molecular weight: 83790.90 Da
• Isoelectric Point: 5.0140

>NTDB_id=163386 ATM98_RS00450 WP_061563681.1 76809..79076(-) (clpE) [Streptococcus sp. A12]
MLCQNCKINDSTIHLYTNVNGHQQQVDLCQNCYQIMKTDPNNSLLAGLNQQNRGGRDPFEDFFNQLGNFQAPQEPQTPPT
QSGGGYGGGNGYGSNGNGRSSGPSRPQAKQQPKGLLEEFGINVTEIARSGDIDPVIGRDEEILRVIEILNRRTKNNPVLI
GEPGVGKTAVVEGLAQKIVDGDVPHKLQCKQVIRLDVVSLVQGTGIRGQFEERMQQLMEEIRRREDVILFIDEIHEIVGA
GSAGDGNMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPTVEETITILKGIQKKYEDYHHVHYT
DGAIEAAALLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKAQATRDEDFEKAAYFRDQIAKY
KEMQGQQVTDQDTPVISEKTIEHIVEQKTNIPVGDLKEKEQSQLINLAADLKAHVIGQDEAVEKIAKAIRRNRVGLGTPN
RPIGSFLFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEKVRRNPYSLIL
LDEVEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKAEANVGFGAAREGRTNSILGELGNFFSPEFM
NRFDGIIEFKALSKENLLQIVTLMLDDVNQRLAHNDIHLDVTDKVKEKLVDLGYDPKMGARPLRRTIQDYIEDAITDYYL
ENPSEKDLKAVMTSNGKICIKGKNKPANEAEKVTE

Nucleotide

• Length: 2268 bp

>NTDB_id=163386 ATM98_RS00450 WP_061563681.1 76809..79076(-) (clpE) [Streptococcus sp. A12]
ATGCTTTGTCAAAACTGTAAAATCAACGATTCAACCATTCATCTTTATACGAATGTAAATGGTCACCAACAACAAGTAGA
CCTTTGCCAGAACTGCTATCAAATTATGAAAACCGATCCTAACAATAGCCTCCTTGCAGGATTAAACCAACAAAATCGCG
GAGGACGGGATCCTTTTGAAGATTTCTTCAATCAACTTGGAAACTTCCAGGCTCCGCAAGAACCCCAAACCCCTCCGACC
CAATCTGGAGGAGGCTATGGTGGAGGAAATGGCTATGGCTCAAATGGGAACGGACGTTCTTCAGGACCAAGCAGACCCCA
AGCCAAACAACAACCAAAGGGCCTCCTAGAAGAGTTTGGAATTAACGTTACTGAAATTGCTCGTAGCGGCGATATCGATC
CGGTCATTGGTCGTGATGAAGAGATTCTCCGCGTCATTGAAATCCTCAACCGTCGAACCAAGAACAACCCTGTCCTGATC
GGTGAACCTGGTGTCGGTAAAACTGCTGTCGTAGAAGGGCTAGCTCAAAAGATTGTCGATGGGGATGTCCCTCATAAATT
GCAGTGCAAGCAAGTTATTCGCTTAGACGTTGTTAGTCTTGTTCAAGGAACTGGGATCCGAGGCCAATTTGAAGAGCGTA
TGCAACAATTAATGGAGGAAATCCGTCGCCGTGAAGATGTGATTTTATTCATCGACGAAATTCATGAAATCGTCGGTGCT
GGATCTGCTGGAGACGGCAACATGGATGCTGGAAATATCCTCAAACCAGCCCTCGCTCGTGGCGAATTGCAATTAGTCGG
TGCGACAACACTTAATGAATACCGGATTATCGAGAAGGATGCGGCACTTGAACGCCGGATGCAACCTGTTAAGGTCGATG
AGCCAACGGTTGAAGAAACTATCACCATCCTCAAAGGCATTCAAAAGAAATATGAGGACTACCACCACGTCCACTACACC
GATGGGGCAATCGAGGCTGCAGCTCTCCTTTCCAATCGCTATATCCAAGACCGCTTCTTGCCCGACAAGGCCATTGACCT
CTTGGATGAAGCTGGCTCTAAGATGAATTTAACCCTCAATTTCGTCGATCCAAAGGTCATTGACCAACGCTTAATTGAAG
CTGAAAATCTCAAAGCCCAGGCGACGCGTGATGAAGATTTCGAAAAAGCTGCCTACTTCCGTGACCAAATCGCTAAGTAC
AAAGAAATGCAAGGGCAACAGGTCACTGATCAAGATACGCCAGTTATTAGCGAAAAGACCATCGAACACATCGTTGAGCA
AAAGACCAATATTCCAGTCGGCGATTTGAAAGAAAAAGAACAATCCCAATTGATCAATTTGGCAGCTGATTTGAAAGCTC
ATGTCATCGGCCAAGATGAGGCTGTTGAAAAAATTGCTAAGGCCATCCGTCGCAACCGGGTAGGACTTGGAACGCCAAAC
CGTCCAATCGGTAGCTTCCTCTTTGTTGGACCAACCGGTGTCGGGAAGACAGAGTTGTCCAAACAATTAGCTATCGAACT
CTTCGGTTCTGCTGACAGCATGATTCGCTTTGATATGAGTGAATATATGGAGAAACATGCCGTTGCCAAATTGGTCGGTG
CTCCTCCAGGCTACGTCGGCTATGAAGAAGCAGGCCAGCTGACTGAAAAGGTGCGTCGCAACCCATACTCTCTCATTCTC
TTGGATGAGGTCGAAAAGGCCCACCCAGATGTCATGCATATGTTCCTCCAAGTCTTAGACGATGGGCGCTTGACAGATGG
GCAAGGCCGAACGGTGAGCTTCAAAGATACCATTATTATCATGACTTCCAATGCGGGAACTGGAAAAGCGGAGGCTAATG
TCGGCTTTGGGGCAGCTCGTGAAGGTCGTACCAATTCTATCCTAGGTGAACTGGGGAACTTCTTCAGTCCAGAATTCATG
AACCGCTTTGACGGCATCATTGAATTCAAAGCCTTGTCTAAGGAAAACCTCCTTCAAATCGTCACTCTCATGTTAGACGA
TGTCAACCAACGCTTGGCCCACAATGATATCCACCTGGATGTTACAGATAAGGTCAAGGAAAAACTGGTTGACCTAGGCT
ACGATCCGAAAATGGGGGCACGCCCACTCCGTCGCACCATTCAAGACTATATCGAAGATGCCATTACAGATTACTACCTA
GAAAATCCTAGTGAAAAAGATCTGAAGGCTGTCATGACCAGCAATGGGAAGATATGTATCAAAGGAAAGAACAAACCTGC
TAATGAGGCAGAAAAAGTAACTGAATAA

Domains

Predicted by InterproScan.

• AAA lid domain (AAA_lid_9) (296-393)

• AAA domain (Cdc48 subfamily) (AAA_2) (481-644)

• ATPase family associated with various cellular activities (AAA) (AAA) (158-277)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (652-726)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus pneumoniae Rx1	87.037	100	0.872
clpE	Streptococcus pneumoniae D39	87.037	100	0.872
clpE	Streptococcus pneumoniae R6	87.037	100	0.872
clpE	Streptococcus pneumoniae TIGR4	87.037	100	0.872
clpE	Streptococcus mutans UA159	85.18	99.205	0.845
clpC	Lactococcus lactis subsp. cremoris KW2	76.19	100	0.763
clpC	Bacillus subtilis subsp. subtilis str. 168	50.808	90.199	0.458
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	48.644	83.046	0.404
clpC	Streptococcus pneumoniae Rx1	48.548	82.119	0.399
clpC	Streptococcus pneumoniae D39	48.548	82.119	0.399
clpC	Streptococcus pneumoniae TIGR4	48.387	82.119	0.397
clpC	Streptococcus thermophilus LMD-9	47.444	82.914	0.393
clpC	Streptococcus thermophilus LMG 18311	47.276	82.649	0.391
clpC	Streptococcus mutans UA159	47.504	82.252	0.391