Detailed information NTG0163311

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: AUC49_RS13285
• Genome accession: NZ_CP013619
• Coordinates: 2664090..2664977 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain RIVM1607
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2659090..2669977

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AUC49_RS13250 (AUC49_13235)	-	2659099..2659191 (+)	93	WP_031774855.1	hypothetical protein	-
AUC49_RS13255 (AUC49_13240)	-	2659299..2659796 (-)	498	WP_001065267.1	glutathione peroxidase	-
AUC49_RS13260 (AUC49_13245)	-	2659806..2660066 (-)	261	WP_014937088.1	hypothetical protein	-
AUC49_RS13265 (AUC49_13250)	-	2660448..2660561 (-)	114	WP_014937089.1	hypothetical protein	-
AUC49_RS13275 (AUC49_13260)	-	2661230..2663230 (-)	2001	WP_000776741.1	ABC transporter permease	-
AUC49_RS13280 (AUC49_13265)	-	2663227..2663982 (-)	756	WP_000923768.1	ABC transporter ATP-binding protein	-
AUC49_RS13285 (AUC49_13270)	braS	2664090..2664977 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
AUC49_RS13290 (AUC49_13275)	braR	2664988..2665653 (-)	666	WP_000697873.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
AUC49_RS13295 (AUC49_13280)	-	2665679..2665879 (-)	201	WP_000604731.1	hypothetical protein	-
AUC49_RS13305 (AUC49_13290)	-	2666077..2667501 (+)	1425	WP_000953736.1	alkaline phosphatase	-
AUC49_RS14950	-	2667561..2667662 (-)	102	WP_000731972.1	SE2200 family small protein	-
AUC49_RS13310 (AUC49_13295)	-	2667784..2668239 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
AUC49_RS13315 (AUC49_13300)	-	2668483..2669244 (-)	762	WP_000323448.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=163311 AUC49_RS13285 WP_000143420.1 2664090..2664977(-) (braS) [Staphylococcus aureus strain RIVM1607]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=163311 AUC49_RS13285 WP_000143420.1 2664090..2664977(-) (braS) [Staphylococcus aureus strain RIVM1607]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTTATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTGGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993