Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   A6L42_RS02045 Genome accession   NZ_CP016671
Coordinates   396844..399135 (-) Length   763 a.a.
NCBI ID   WP_002258152.1    Uniprot ID   -
Organism   Neisseria meningitidis strain M22783     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 391844..404135
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6L42_RS02035 (A6L42_02035) - 392570..393709 (+) 1140 WP_002234786.1 AAA family ATPase -
  A6L42_RS02040 (A6L42_02040) - 393706..396804 (+) 3099 WP_002234787.1 HsdR family type I site-specific deoxyribonuclease -
  A6L42_RS02045 (A6L42_02045) clpC 396844..399135 (-) 2292 WP_002258152.1 ATP-dependent Clp protease ATP-binding subunit ClpA Regulator
  A6L42_RS02050 (A6L42_02050) clpS 399137..399439 (-) 303 WP_002221161.1 ATP-dependent Clp protease adapter ClpS -
  A6L42_RS02055 (A6L42_02055) - 399682..399885 (+) 204 WP_002217533.1 cold-shock protein -
  A6L42_RS02060 (A6L42_02060) pmbA 400182..401513 (-) 1332 WP_002229293.1 metalloprotease PmbA -
  A6L42_RS02065 (A6L42_02065) yjgA 401667..402179 (+) 513 WP_002226469.1 ribosome biogenesis factor YjgA -
  A6L42_RS02070 (A6L42_02070) - 402226..402942 (+) 717 WP_002234789.1 hypothetical protein -

Sequence

Protein


Download         Length: 763 a.a.        Molecular weight: 84338.24 Da        Isoelectric Point: 6.6775

>NTDB_id=162879 A6L42_RS02045 WP_002258152.1 396844..399135(-) (clpC) [Neisseria meningitidis strain M22783]
MLAPELEQILQQLYREARKAHYEFISLEHLLLVLIEEDASVPNVLKLCGADLKVVSEQLAASVAENTPLIPEHLLDTVET
RPTLGFQRVMQRAMVHTQSAGKAAVEPLDVLVALMSETDSHTVYFLKLQSVTRFEVLRCIAHGSPDEDEDDGNYSSDGMD
DDNENRTKPGKNPLSAYTVNLNAEVKAGRIDPLIGRKHEMERLVQILCRRRKNNPLLVGEAGVGKTALAEGLAHQIVNGG
IPDALKDAEVYALDMGSLLAGTKYRGDFEARVKSVLKQLEKIPHAILFIDEIHTIIGAGSTSGGTMDASNLLKPALAKGS
LRCIGATTYDEYRTIFDKDHALSRRFQKIDVVEPTVSETVQILRGLKPMFEAFHQVRYTQGALEAAAELSARYINERFLP
DKAIDVMDEAGAAQRILPKSKQKKVIGKAQIETVIAKVARIPEKTVSHDDKQVLQFLDRDLKNMVYGQENAIDALVTAVK
MSRSGLALPDKPIGSFLFSGPTGVGKTEAAKQLAYSMGVPLQRFDMSEYMERHAVSRLIGAPPGYVGFEQGGLLTEAVNK
QPHCVLLLDEIEKAHPDIFNVLLQVMDAGKLTDNNGKSADFRNVILIMTTNAGAESLSRPGLGFTAKREHGDEMQAINKL
FTPEFRNRLDAIIPFAPLSEPIIVKVVDKFLLQLEHQLLDKKVEAEFTPALHKYLAEKGFDPQMGARPMHRLIQEKIRKP
LADELLFGKLSDGGFVRIDWDAAKEEAVLKFKKSKVKIKTALA

Nucleotide


Download         Length: 2292 bp        

>NTDB_id=162879 A6L42_RS02045 WP_002258152.1 396844..399135(-) (clpC) [Neisseria meningitidis strain M22783]
ATGCTTGCACCCGAATTGGAACAGATTTTGCAGCAGCTTTACCGCGAGGCGCGTAAGGCTCATTATGAATTTATCAGCCT
CGAGCATCTGCTTTTGGTACTCATCGAAGAAGATGCCTCCGTGCCGAACGTCTTAAAACTCTGCGGCGCGGATTTGAAAG
TGGTGTCCGAACAGCTCGCCGCCAGCGTTGCCGAAAACACCCCCCTGATTCCCGAACACCTTTTAGACACGGTCGAAACC
CGGCCCACGCTCGGCTTCCAACGCGTGATGCAACGGGCGATGGTGCATACCCAGTCTGCCGGAAAAGCCGCAGTCGAACC
GTTGGACGTTTTGGTCGCGCTGATGAGCGAAACCGACAGCCACACCGTCTATTTCCTCAAGCTGCAATCGGTTACGCGTT
TTGAAGTTTTGCGCTGTATTGCCCACGGCTCTCCCGATGAAGATGAAGACGATGGCAACTATTCTTCAGACGGCATGGAC
GACGATAATGAAAACCGCACCAAACCGGGCAAAAACCCTTTATCGGCGTACACCGTCAACCTCAACGCCGAAGTCAAAGC
CGGCCGTATCGACCCTTTGATTGGTCGCAAACACGAAATGGAACGGCTGGTGCAAATCCTATGCCGCCGCCGCAAAAACA
ATCCGCTTTTGGTCGGCGAAGCGGGCGTGGGCAAAACCGCGCTGGCGGAAGGGCTGGCACATCAAATCGTCAACGGCGGC
ATTCCAGACGCGCTCAAAGATGCCGAAGTGTACGCGCTGGATATGGGCTCGCTGTTGGCGGGCACGAAATACCGCGGCGA
CTTTGAAGCGCGGGTCAAATCCGTCTTGAAACAGCTCGAAAAAATCCCGCACGCCATTTTGTTTATCGACGAAATCCACA
CCATCATCGGCGCAGGCAGCACCAGCGGCGGCACCATGGACGCGTCCAACCTGCTCAAACCCGCGCTGGCAAAAGGTTCG
CTGCGCTGCATCGGCGCGACCACTTACGACGAATACCGCACCATTTTCGACAAAGACCACGCCTTAAGCCGCCGCTTCCA
AAAAATCGACGTGGTCGAACCCACCGTTTCCGAAACCGTACAAATCCTGCGCGGCTTGAAGCCGATGTTTGAAGCCTTCC
ACCAAGTCCGCTATACGCAAGGCGCACTCGAAGCCGCCGCCGAACTCTCCGCACGCTACATCAACGAGCGTTTCCTGCCC
GACAAAGCCATCGACGTGATGGACGAAGCAGGCGCGGCGCAACGGATTCTGCCCAAATCCAAACAGAAAAAAGTCATCGG
CAAAGCACAAATTGAAACCGTCATCGCCAAAGTCGCGCGGATTCCCGAAAAAACCGTGTCGCACGACGACAAACAAGTGT
TGCAATTCCTCGACCGCGATTTGAAAAACATGGTTTACGGTCAGGAAAACGCCATCGACGCGTTGGTTACCGCCGTCAAA
ATGTCGCGCTCCGGCCTTGCCCTGCCCGACAAACCGATAGGCAGTTTCCTCTTCTCCGGTCCGACCGGCGTGGGCAAAAC
CGAAGCCGCCAAACAGCTTGCCTACTCGATGGGCGTACCGCTGCAACGCTTTGATATGTCCGAATACATGGAACGCCATG
CCGTATCACGACTCATCGGCGCGCCTCCGGGCTACGTCGGCTTTGAACAAGGCGGCCTTTTGACCGAAGCCGTCAACAAA
CAGCCGCATTGCGTGTTGCTCTTGGACGAAATCGAAAAAGCCCACCCCGACATTTTCAACGTCCTCCTGCAAGTCATGGA
CGCAGGCAAACTGACCGACAACAACGGCAAGAGTGCCGATTTCCGCAACGTCATCCTAATCATGACCACCAACGCGGGCG
CGGAAAGCCTCAGCCGCCCTGGCCTCGGCTTTACCGCCAAGCGCGAACACGGCGACGAAATGCAGGCAATCAACAAGCTC
TTCACGCCCGAGTTCCGCAACCGCTTGGACGCGATTATCCCATTTGCACCCTTGTCCGAACCCATCATCGTCAAAGTCGT
GGACAAATTCCTGCTCCAGCTCGAACACCAGCTTCTCGACAAAAAAGTCGAAGCCGAATTCACGCCCGCATTGCACAAAT
ATCTGGCGGAAAAAGGTTTCGACCCGCAAATGGGCGCGCGCCCGATGCACCGTCTGATTCAGGAAAAAATCCGCAAACCG
CTCGCCGACGAACTCCTGTTCGGCAAACTATCCGACGGCGGCTTCGTGCGGATAGACTGGGATGCGGCAAAAGAAGAAGC
CGTGTTGAAGTTTAAGAAAAGCAAGGTCAAAATAAAAACCGCCCTCGCATGA

Domains

Predicted by InterProScan.

Clp amino terminal domain, pathogenicity island component (Clp_N)

(15-61)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(658-738)

ATPase family associated with various cellular activities (AAA) (AAA)

(216-348)

AAA domain (Cdc48 subfamily) (AAA_2)

(491-652)

AAA lid domain (AAA_lid_9)

(356-454)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

38.773

100

0.414
  clpC Bacillus subtilis subsp. subtilis str. 168

38.213

100

0.404
  clpA Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

41.586

94.233

0.392
  clpC Streptococcus thermophilus LMG 18311

45.082

79.948

0.36

Multiple sequence alignment