Detailed information NTG0162701

Bioinformatically predicted

Overview

• Name: pilD
• Type: Machinery gene
• Locus tag: A6M04_RS07345
• Genome accession: NZ_CP016668
• Coordinates: 1424971..1425831 (+)
• Length: 286 a.a.
• NCBI ID: WP_002241067.1
• Uniprot ID: -
• Organism: Neisseria meningitidis strain M25472
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1419971..1430831

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A6M04_RS07320 (A6M04_07320)	-	1420229..1420459 (-)	231	WP_025462060.1	hypothetical protein	-
A6M04_RS07325 (A6M04_07325)	pgi	1420429..1422072 (-)	1644	WP_002247959.1	glucose-6-phosphate isomerase	-
A6M04_RS07330 (A6M04_07330)	pilG	1422582..1423307 (+)	726	Protein_1369	type 4 pilus assembly protein PilG	-
A6M04_RS07335 (A6M04_07335)	-	1423398..1424363 (+)	966	WP_002216744.1	IS30-like element IS1655 family transposase	-
A6M04_RS07340 (A6M04_07340)	pilG	1424391..1424897 (+)	507	Protein_1371	type 4 pilus assembly protein PilG	-
A6M04_RS07345 (A6M04_07345)	pilD	1424971..1425831 (+)	861	WP_002241067.1	prepilin peptidase	Machinery gene
A6M04_RS07350 (A6M04_07350)	coaE	1425833..1426465 (+)	633	WP_002216402.1	dephospho-CoA kinase	-
A6M04_RS07355 (A6M04_07355)	-	1426458..1426667 (+)	210	WP_002216401.1	DNA gyrase inhibitor YacG	-
A6M04_RS07360 (A6M04_07360)	pilF	1426752..1428428 (-)	1677	WP_002221967.1	type IV-A pilus assembly ATPase PilB	Machinery gene
A6M04_RS07370 (A6M04_07370)	-	1428920..1429366 (-)	447	WP_002220271.1	DUF441 domain-containing protein	-
A6M04_RS07375 (A6M04_07375)	ispB	1429371..1430345 (-)	975	WP_002247958.1	octaprenyl diphosphate synthase	-

Sequence

Protein

• Length: 286 a.a.
• Molecular weight: 31331.48 Da
• Isoelectric Point: 9.1920

>NTDB_id=162701 A6M04_RS07345 WP_002241067.1 1424971..1425831(+) (pilD) [Neisseria meningitidis strain M25472]
MSDLSVLSPFAVPLAAVFGLLVGSFLNVVIYRVPVMMERGWTVFAKKHLNLPLTEKESRTFNLMKPDSCCPKCRVPIRAW
QNIPIVSYLLLRGKCASCQTKISIRYPLIELLTGVLFGLVAWQYGWSWITLGGLILTAFLISLTFIDADTQYLPDSMTLP
LIWLGLIFNLDGGFVPLQSAVLGAVAGYGSIWLLCAVYKLIKGEIGMGNGDFKLIAALGAWLGISALPVLIFVSSLIGLV
AAIVMRVAKGQHFAFGPALTVSGWIIFTANDSVWRAVNWWLTHPVL

Nucleotide

• Length: 861 bp

>NTDB_id=162701 A6M04_RS07345 WP_002241067.1 1424971..1425831(+) (pilD) [Neisseria meningitidis strain M25472]
ATGTCTGATTTGTCTGTATTGTCGCCGTTTGCCGTGCCTTTGGCAGCGGTGTTCGGGCTGCTGGTCGGCAGTTTCTTAAA
CGTCGTCATTTACCGCGTGCCGGTCATGATGGAACGCGGCTGGACGGTATTTGCCAAAAAACATTTAAACCTGCCGCTGA
CCGAAAAGGAAAGCCGTACCTTCAACCTGATGAAACCGGATTCCTGCTGTCCCAAATGCCGCGTGCCGATACGCGCGTGG
CAGAACATCCCGATTGTCAGCTACCTGCTCCTGCGCGGCAAATGCGCTTCCTGCCAAACCAAAATCAGCATACGTTATCC
CTTAATCGAGCTGCTGACCGGCGTATTATTCGGGCTGGTCGCCTGGCAATACGGCTGGTCTTGGATTACATTGGGCGGTT
TGATACTGACCGCGTTTCTGATTTCCCTGACCTTTATCGATGCGGACACCCAATACCTGCCCGACTCGATGACACTGCCC
TTGATTTGGCTGGGGCTGATATTTAATTTGGACGGCGGCTTCGTGCCTTTGCAGTCTGCCGTTTTAGGTGCGGTTGCCGG
CTATGGTTCGATATGGCTTTTATGCGCGGTATATAAACTGATTAAAGGCGAAATCGGTATGGGCAACGGAGATTTCAAAC
TGATTGCCGCATTGGGCGCGTGGCTCGGCATATCCGCATTGCCCGTGCTGATTTTTGTTTCCTCGCTGATCGGTTTGGTC
GCGGCAATCGTTATGCGCGTCGCCAAGGGGCAGCATTTTGCCTTCGGCCCCGCACTGACAGTTTCGGGCTGGATAATTTT
TACGGCAAACGATTCCGTATGGCGGGCGGTCAACTGGTGGCTGACCCATCCGGTGCTGTAA

Domains

Predicted by InterProScan.

• Type IV leader peptidase family (Peptidase_A24) (134-242)

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (17-124)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilD	Neisseria gonorrhoeae MS11	96.14	99.65	0.958
pilD	Vibrio cholerae strain A1552	44.444	100	0.448
pilD	Acinetobacter baumannii D1279779	46.97	92.308	0.434
pilD	Acinetobacter nosocomialis M2	46.97	92.308	0.434
pilD	Vibrio campbellii strain DS40M4	44.565	96.503	0.43