Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   A6M04_RS01835 Genome accession   NZ_CP016668
Coordinates   349954..352251 (-) Length   765 a.a.
NCBI ID   WP_002221163.1    Uniprot ID   -
Organism   Neisseria meningitidis strain M25472     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 344954..357251
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6M04_RS01815 (A6M04_01815) hldA 345482..346453 (+) 972 WP_002217546.1 ADP-heptose synthase -
  A6M04_RS01820 (A6M04_01820) - 346490..347725 (+) 1236 WP_002221168.1 DNA cytosine methyltransferase -
  A6M04_RS01825 (A6M04_01825) - 347727..348845 (+) 1119 WP_002221166.1 HNH endonuclease -
  A6M04_RS01830 (A6M04_01830) rfaD 348886..349890 (+) 1005 WP_002221165.1 ADP-glyceromanno-heptose 6-epimerase -
  A6M04_RS01835 (A6M04_01835) clpC 349954..352251 (-) 2298 WP_002221163.1 ATP-dependent Clp protease ATP-binding subunit ClpA Regulator
  A6M04_RS01840 (A6M04_01840) clpS 352253..352555 (-) 303 WP_002221161.1 ATP-dependent Clp protease adapter ClpS -
  A6M04_RS01845 (A6M04_01845) - 352798..353001 (+) 204 WP_002217533.1 cold-shock protein -
  A6M04_RS01850 (A6M04_01850) pmbA 353298..354629 (-) 1332 WP_002221160.1 metalloprotease PmbA -
  A6M04_RS01855 (A6M04_01855) yjgA 354784..355290 (+) 507 WP_002224594.1 ribosome biogenesis factor YjgA -
  A6M04_RS01860 (A6M04_01860) - 355337..356071 (+) 735 WP_002221158.1 hypothetical protein -

Sequence

Protein


Download         Length: 765 a.a.        Molecular weight: 84475.28 Da        Isoelectric Point: 6.6432

>NTDB_id=162670 A6M04_RS01835 WP_002221163.1 349954..352251(-) (clpC) [Neisseria meningitidis strain M25472]
MLAPELEQILQQLYREARKAHYEFISLEHLLLVLIEEDASVPNVLKLCGADLKVVSEQLAASVAENTPLIPEHLLDTVET
RPTLGFQRVMQRAMVHTQSAGKAAVEPLDVLVALMSETDSHTVYFLKLQSVTRFEVLRCIAHGSPDEDEDEDDGNYSSDG
MDDDNENRAKPGKNPLSAYTVNLNAEVKAGRIDPLIGRKHEMERLVQILCRRRKNNPLLVGEAGVGKTALAEGLAHQIVN
GGIPDALKDAEVYALDMGSLLAGTKYRGDFEARVKSVLKQLEKIPHAILFIDEIHTIIGAGSTSGGTMDASNLLKPALAK
GSLRCIGATTYDEYRTIFDKDHALSRRFQKIDVVEPTVSETVQILRGLKPMFEAFHQVRYTQGALEAAAELSARYINERF
LPDKAIDVMDEAGAAQRILPKSKQKKVIGKAQIETVIAKVSRIPEKTVSHDDKQVLQFLGRDLKNMVYGQENAIDALVAA
VKMSRSGLALPDKPIGSFLFSGPTGVGKTEAAKQLAYSLGVPLQRFDMSEYMERHAVSRLIGAPPGYVGFEQGGLLTEAV
NKQPHCVLLLDEIEKAHPDIFNVLLQVMDAGKLTDNNGKSADFRNVILIMTTNAGAESLSRPSLGFTAKRERGDEMQAIN
KLFTPEFRNRLDAIIPFAPLSEPIIVKVVDKFLLQLEHQLLDKKVEAEFTSALHKYLAEKGFDPQMGARPMHRLIQEKIR
KPLADELLFGKLSDGGFVRIDWDAAKEEAVLKFKKSKVKIKTASA

Nucleotide


Download         Length: 2298 bp        

>NTDB_id=162670 A6M04_RS01835 WP_002221163.1 349954..352251(-) (clpC) [Neisseria meningitidis strain M25472]
ATGCTTGCACCCGAATTGGAACAGATTTTGCAGCAGCTTTACCGCGAGGCGCGTAAGGCTCATTATGAATTTATCAGCCT
CGAGCATCTGCTTTTGGTACTCATCGAAGAAGATGCCTCCGTGCCGAACGTCTTAAAACTATGCGGCGCGGATTTGAAAG
TGGTGTCCGAACAGCTCGCCGCCAGCGTTGCCGAAAACACCCCCCTGATTCCCGAACACCTTTTAGACACGGTCGAAACA
CGGCCCACGCTCGGCTTCCAACGCGTGATGCAACGGGCGATGGTGCATACCCAGTCTGCCGGAAAAGCCGCAGTCGAACC
GTTGGACGTTTTGGTCGCGCTGATGAGCGAAACCGACAGCCACACCGTCTATTTCCTCAAGCTGCAATCGGTTACGCGTT
TTGAAGTTTTGCGCTGTATTGCCCACGGCTCTCCCGATGAAGATGAAGATGAAGACGATGGCAACTATTCTTCAGACGGC
ATGGACGACGATAATGAAAACCGCGCCAAACCGGGCAAAAACCCTTTATCGGCGTACACCGTCAACCTCAACGCCGAAGT
CAAAGCCGGCCGTATCGACCCTTTGATTGGTCGCAAACACGAAATGGAACGGCTGGTGCAAATCCTATGCCGCCGCCGCA
AAAACAATCCGCTTTTGGTCGGCGAAGCGGGCGTGGGCAAAACCGCGCTGGCGGAAGGTTTGGCACATCAAATCGTCAAC
GGCGGCATTCCAGACGCGCTCAAAGATGCCGAAGTGTACGCGCTGGATATGGGCTCGCTGTTGGCGGGCACGAAATACCG
CGGCGACTTTGAAGCGCGGGTCAAATCCGTCTTGAAACAGCTCGAAAAAATCCCGCACGCCATTTTGTTTATCGACGAAA
TCCACACCATCATCGGCGCGGGCAGCACCAGCGGCGGCACCATGGACGCGTCCAACCTGCTCAAACCCGCGCTGGCAAAA
GGTTCGCTGCGCTGCATCGGCGCGACCACCTACGACGAATACCGCACCATTTTCGACAAAGACCATGCCTTAAGCCGCCG
CTTCCAAAAAATCGACGTGGTCGAACCCACCGTTTCCGAAACCGTTCAAATCCTGCGCGGCTTGAAACCGATGTTTGAAG
CCTTCCACCAAGTCCGCTACACTCAAGGCGCACTCGAAGCCGCCGCCGAACTCTCCGCACGCTACATCAACGAGCGTTTC
CTGCCCGACAAAGCCATCGACGTAATGGATGAAGCAGGCGCGGCGCAACGGATTCTGCCCAAATCCAAACAGAAAAAAGT
CATCGGCAAAGCACAAATCGAAACCGTCATCGCCAAAGTTTCGCGGATTCCCGAAAAAACCGTGTCGCACGACGACAAAC
AAGTGCTGCAATTCCTCGGTCGCGATTTGAAAAACATGGTTTACGGTCAAGAAAACGCCATCGACGCGCTGGTTGCCGCC
GTCAAAATGTCGCGTTCCGGCCTTGCCCTGCCCGACAAACCGATAGGCAGCTTCCTCTTCTCCGGCCCGACCGGCGTGGG
CAAAACCGAAGCCGCCAAACAGCTTGCCTACTCGCTGGGCGTACCGCTGCAACGCTTTGATATGTCCGAATACATGGAAC
GCCATGCCGTATCGCGCCTCATCGGCGCGCCACCGGGCTACGTCGGCTTTGAACAAGGCGGCCTTTTGACCGAAGCCGTC
AACAAACAGCCGCATTGCGTATTGCTCTTGGACGAAATCGAAAAAGCCCACCCCGACATTTTCAACGTCCTCCTGCAAGT
CATGGACGCAGGCAAACTGACCGACAACAACGGCAAGAGTGCCGATTTCCGCAACGTCATCCTGATTATGACCACCAACG
CAGGCGCGGAAAGCCTCAGCCGCCCCAGCCTCGGCTTTACCGCCAAGCGCGAACGCGGCGACGAAATGCAGGCAATCAAC
AAGCTCTTCACGCCCGAGTTCCGCAACCGCTTGGACGCGATTATCCCGTTTGCACCCTTGTCCGAACCCATCATCGTCAA
AGTCGTGGACAAATTCCTGCTCCAGCTCGAACACCAGCTCCTCGACAAAAAAGTCGAAGCCGAATTCACGTCGGCATTGC
ACAAATATCTGGCGGAAAAAGGTTTCGACCCGCAAATGGGCGCGCGCCCGATGCACCGCCTGATTCAGGAAAAAATCCGC
AAACCGCTCGCCGACGAACTCCTGTTCGGCAAACTATCCGACGGCGGCTTCGTGCGGATAGACTGGGATGCGGCAAAAGA
AGAAGCCGTGTTGAAGTTTAAGAAAAGCAAGGTCAAAATAAAAACCGCCTCCGCGTAA

Domains

Predicted by InterProScan.

Clp amino terminal domain, pathogenicity island component (Clp_N)

(15-61)

ATPase family associated with various cellular activities (AAA) (AAA)

(218-350)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(660-740)

AAA domain (Cdc48 subfamily) (AAA_2)

(493-654)

AAA lid domain (AAA_lid_9)

(358-455)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

38.386

100

0.41
  clpC Bacillus subtilis subsp. subtilis str. 168

37.129

100

0.392
  clpA Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

41.609

94.248

0.392