Detailed information    

insolico Bioinformatically predicted

Overview

Name   hdrM   Type   Regulator
Locus tag   APQ13_RS09135 Genome accession   NZ_CP013237
Coordinates   1884164..1884850 (-) Length   228 a.a.
NCBI ID   WP_002268420.1    Uniprot ID   -
Organism   Streptococcus mutans strain NG8 isolate Dental Plaque     
Function   repress competence development; negative regulate HdrR activity (predicted from homology)   
Competence regulation

Genomic Context

Location: 1879164..1889850
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  APQ13_RS09105 (APQ13_09085) - 1881138..1881341 (-) 204 WP_002267523.1 hypothetical protein -
  APQ13_RS09110 (APQ13_09090) - 1881646..1881891 (+) 246 WP_002263367.1 hypothetical protein -
  APQ13_RS09115 (APQ13_09095) rpsF 1882047..1882337 (+) 291 WP_002261866.1 30S ribosomal protein S6 -
  APQ13_RS09120 (APQ13_09100) ssbA 1882355..1882849 (+) 495 WP_002261867.1 single-stranded DNA-binding protein Machinery gene
  APQ13_RS09125 (APQ13_09105) rpsR 1882879..1883118 (+) 240 WP_000068664.1 30S ribosomal protein S18 -
  APQ13_RS09130 (APQ13_09110) - 1883437..1884156 (+) 720 WP_002278468.1 TraX family protein -
  APQ13_RS09135 (APQ13_09115) hdrM 1884164..1884850 (-) 687 WP_002268420.1 hdrR negative regulator HdrM Regulator
  APQ13_RS10230 (APQ13_09120) hdrR 1884847..1885203 (-) 357 WP_002265268.1 LytTR family transcriptional regulator HdrR Regulator
  APQ13_RS09145 (APQ13_09125) - 1885342..1886004 (-) 663 WP_002265267.1 DUF1129 domain-containing protein -
  APQ13_RS09150 (APQ13_09130) - 1886287..1887231 (-) 945 WP_002262667.1 magnesium transporter CorA family protein -
  APQ13_RS09155 (APQ13_09135) - 1887631..1887852 (-) 222 WP_019317773.1 hypothetical protein -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 26101.17 Da        Isoelectric Point: 6.7581

>NTDB_id=161024 APQ13_RS09135 WP_002268420.1 1884164..1884850(-) (hdrM) [Streptococcus mutans strain NG8 isolate Dental Plaque]
MKKNYFWYGLLGLLALYLITIAFIPGFHIFFSNMLMLALFFMLIALSNRSIFFFFLALGFLSIYLKDIFHFDYSTGPLFT
GIIIIGVILNSFLKPHYSYSYKGNHYFNMKQNANYIDNETDVFLKTLFSENTSYVTSQELNKIIIDTKFGEQSVDLSQAQ
FMTDSPEIHIDISFGETNLRIPNNWKIINKTHSPFASISFSGFPSTNGDFINVTLTGTVAMGSLNIQY

Nucleotide


Download         Length: 687 bp        

>NTDB_id=161024 APQ13_RS09135 WP_002268420.1 1884164..1884850(-) (hdrM) [Streptococcus mutans strain NG8 isolate Dental Plaque]
ATGAAAAAAAATTATTTTTGGTACGGTCTGCTTGGGCTTCTCGCACTTTACCTTATTACTATTGCTTTTATCCCGGGATT
TCATATTTTCTTTAGCAACATGTTGATGTTGGCCCTGTTCTTTATGTTAATAGCTTTGAGTAACAGGAGTATCTTCTTTT
TCTTTCTAGCCTTAGGTTTTCTTAGTATCTACTTGAAAGATATCTTTCATTTTGACTATTCTACCGGACCGCTTTTTACG
GGTATAATCATTATCGGCGTTATTTTAAATAGTTTCCTCAAACCACACTATTCTTATTCTTATAAAGGAAATCATTATTT
TAATATGAAACAAAATGCTAACTACATTGATAACGAAACAGATGTCTTTTTAAAAACACTTTTTTCTGAAAATACCAGTT
ATGTGACTTCTCAAGAATTAAATAAAATTATTATTGATACTAAGTTTGGAGAACAATCTGTTGATCTCTCTCAAGCTCAA
TTTATGACAGATTCTCCCGAAATTCATATAGATATTAGCTTTGGTGAAACCAATCTGCGTATTCCAAACAACTGGAAAAT
CATCAATAAAACTCACTCTCCCTTTGCTTCCATTTCATTTTCAGGTTTTCCTAGCACAAATGGTGATTTTATTAACGTTA
CATTGACTGGAACAGTGGCTATGGGATCTCTAAACATTCAATATTAA

Domains

Predicted by InterproScan.

Cell wall-active antibiotics response 4TMS YvqF (LiaF-like_C)

(128-205)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hdrM Streptococcus mutans UA159

99.123

100

0.991

Multiple sequence alignment