Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   APQ13_RS03455 Genome accession   NZ_CP013237
Coordinates   716793..718025 (-) Length   410 a.a.
NCBI ID   WP_002262816.1    Uniprot ID   A0AAX1K4W9
Organism   Streptococcus mutans strain NG8 isolate Dental Plaque     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 711793..723025
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  APQ13_RS03435 (APQ13_03430) - 712123..713385 (+) 1263 WP_002281996.1 PLP-dependent aminotransferase family protein -
  APQ13_RS03440 (APQ13_03435) mmuM 713519..714469 (-) 951 WP_002262819.1 homocysteine S-methyltransferase -
  APQ13_RS03445 (APQ13_03440) - 714479..715855 (-) 1377 WP_002262818.1 amino acid permease -
  APQ13_RS03450 (APQ13_03445) yihA 716184..716777 (-) 594 WP_002262817.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  APQ13_RS03455 (APQ13_03450) clpX 716793..718025 (-) 1233 WP_002262816.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  APQ13_RS03460 (APQ13_03455) - 718050..718220 (-) 171 WP_002262815.1 hypothetical protein -
  APQ13_RS03465 (APQ13_03460) - 718238..718750 (-) 513 WP_002271091.1 dihydrofolate reductase -
  APQ13_RS03470 (APQ13_03465) pnuC 718835..719614 (-) 780 WP_002264318.1 nicotinamide riboside transporter PnuC -
  APQ13_RS03475 (APQ13_03470) - 719731..720570 (-) 840 WP_002264319.1 thymidylate synthase -
  APQ13_RS03480 (APQ13_03475) - 720778..721953 (+) 1176 WP_002273854.1 hydroxymethylglutaryl-CoA synthase -

Sequence

Protein


Download         Length: 410 a.a.        Molecular weight: 45181.65 Da        Isoelectric Point: 4.4495

>NTDB_id=160970 APQ13_RS03455 WP_002262816.1 716793..718025(-) (clpX) [Streptococcus mutans strain NG8 isolate Dental Plaque]
MAGNRTNDVTVHCSFCGKNQDEVKKIIAGNGVFICNECVELSQEIIREELAEEVLADLSEVPKPKELLAILDSYVIGQDR
AKRALAVAVYNHYKRISFTESQDDQDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVENI
LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQIDTK
NILFIVGGAFDGIEDIVKQRLGEKIIGFGQNNKKIDDQSSYMQEIISEDIQKFGLIPEFIGRLPVLAALEQLTVDDLVKI
LTEPKNALVKQYQTLLSYDGVELEFDQEALQAIAQKAIERKTGARGLRSIIEETMLDLMFEIPSQEDVTCVRITKKAVEG
TDKPILETAS

Nucleotide


Download         Length: 1233 bp        

>NTDB_id=160970 APQ13_RS03455 WP_002262816.1 716793..718025(-) (clpX) [Streptococcus mutans strain NG8 isolate Dental Plaque]
ATGGCTGGAAATAGAACCAATGATGTCACAGTGCATTGTTCATTCTGTGGCAAAAATCAAGATGAAGTTAAAAAAATTAT
TGCAGGTAATGGCGTTTTTATTTGCAATGAATGTGTTGAATTATCACAAGAAATTATCCGTGAAGAACTAGCAGAAGAGG
TATTGGCTGATCTTTCAGAAGTTCCAAAACCAAAAGAATTATTGGCAATACTAGACAGTTATGTTATCGGTCAGGACCGT
GCCAAACGTGCTTTAGCAGTTGCTGTCTATAATCATTATAAGCGTATCAGTTTTACTGAGAGCCAAGACGACCAAGATGT
TGACTTACAAAAATCAAATATTCTTATGATTGGACCGACAGGTTCTGGAAAAACTTTCTTAGCACAGACTTTGGCTAAGA
GTCTCAATGTGCCCTTTGCTATTGCTGATGCAACAGCCTTGACTGAAGCGGGTTATGTAGGTGAAGATGTTGAAAACATC
TTGCTTAAATTGATTCAGGCAGCTGATTATAATGTTGAACGCGCGGAGCGTGGCATCATTTATGTTGATGAAATTGATAA
GATTGCTAAAAAAGGCGAAAATGTTTCCATCACACGTGATGTATCTGGTGAAGGTGTCCAACAAGCTCTGCTTAAGATTA
TTGAAGGAACAGTAGCTAGTGTGCCACCACAAGGTGGTCGGAAACATCCCCAACAGGAAATGATTCAAATTGATACGAAA
AACATCCTCTTCATAGTTGGTGGCGCTTTTGATGGTATTGAAGATATCGTTAAACAGCGTTTGGGTGAGAAAATTATTGG
CTTTGGTCAAAATAATAAGAAGATTGATGATCAATCTTCTTATATGCAAGAAATTATTTCAGAAGACATTCAAAAATTTG
GTCTTATTCCAGAGTTTATTGGTCGTTTGCCAGTTTTAGCTGCGCTTGAGCAATTAACGGTTGATGATTTGGTTAAGATT
TTGACAGAACCTAAAAATGCTTTAGTTAAACAATATCAGACACTTTTATCTTATGATGGTGTTGAGCTTGAGTTTGATCA
AGAGGCGCTTCAAGCGATTGCTCAAAAGGCGATTGAACGTAAGACAGGCGCACGCGGTCTTCGCTCTATTATTGAAGAAA
CGATGCTGGATCTGATGTTTGAAATTCCGAGTCAAGAGGATGTCACTTGCGTTCGCATTACTAAGAAAGCGGTAGAAGGG
ACCGACAAACCTATTCTTGAGACAGCTTCCTAA

Domains

Predicted by InterproScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(312-388)

AAA domain (Cdc48 subfamily) (AAA_2)

(110-305)

ClpX C4-type zinc finger (zf-C4_ClpX)

(12-48)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

100

100

1
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

59.102

97.805

0.578

Multiple sequence alignment