Detailed information NTG0160914

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: A6L32_RS10910
• Genome accession: NZ_CP016627
• Coordinates: 2102905..2105202 (+)
• Length: 765 a.a.
• NCBI ID: WP_002221163.1
• Uniprot ID: -
• Organism: Neisseria meningitidis strain M22718
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 2097905..2110202

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A6L32_RS10885 (A6L32_10885)	-	2099085..2099819 (-)	735	WP_002221158.1	hypothetical protein	-
A6L32_RS10890 (A6L32_10890)	yjgA	2099866..2100372 (-)	507	WP_002224594.1	ribosome biogenesis factor YjgA	-
A6L32_RS10895 (A6L32_10895)	pmbA	2100527..2101858 (+)	1332	WP_002221160.1	metalloprotease PmbA	-
A6L32_RS10900 (A6L32_10900)	-	2102155..2102358 (-)	204	WP_002217533.1	cold-shock protein	-
A6L32_RS10905 (A6L32_10905)	clpS	2102601..2102903 (+)	303	WP_002221161.1	ATP-dependent Clp protease adapter ClpS	-
A6L32_RS10910 (A6L32_10910)	clpC	2102905..2105202 (+)	2298	WP_002221163.1	ATP-dependent Clp protease ATP-binding subunit ClpA	Regulator
A6L32_RS10915 (A6L32_10915)	rfaD	2105266..2106270 (-)	1005	WP_002221165.1	ADP-glyceromanno-heptose 6-epimerase	-
A6L32_RS10920 (A6L32_10920)	-	2106311..2107429 (-)	1119	WP_002221166.1	HNH endonuclease	-
A6L32_RS10925 (A6L32_10925)	-	2107431..2108666 (-)	1236	WP_002221168.1	DNA cytosine methyltransferase	-
A6L32_RS10930 (A6L32_10930)	hldA	2108703..2109674 (-)	972	WP_002217546.1	ADP-heptose synthase	-

Sequence

Protein

• Length: 765 a.a.
• Molecular weight: 84475.28 Da
• Isoelectric Point: 6.6432

>NTDB_id=160914 A6L32_RS10910 WP_002221163.1 2102905..2105202(+) (clpC) [Neisseria meningitidis strain M22718]
MLAPELEQILQQLYREARKAHYEFISLEHLLLVLIEEDASVPNVLKLCGADLKVVSEQLAASVAENTPLIPEHLLDTVET
RPTLGFQRVMQRAMVHTQSAGKAAVEPLDVLVALMSETDSHTVYFLKLQSVTRFEVLRCIAHGSPDEDEDEDDGNYSSDG
MDDDNENRAKPGKNPLSAYTVNLNAEVKAGRIDPLIGRKHEMERLVQILCRRRKNNPLLVGEAGVGKTALAEGLAHQIVN
GGIPDALKDAEVYALDMGSLLAGTKYRGDFEARVKSVLKQLEKIPHAILFIDEIHTIIGAGSTSGGTMDASNLLKPALAK
GSLRCIGATTYDEYRTIFDKDHALSRRFQKIDVVEPTVSETVQILRGLKPMFEAFHQVRYTQGALEAAAELSARYINERF
LPDKAIDVMDEAGAAQRILPKSKQKKVIGKAQIETVIAKVSRIPEKTVSHDDKQVLQFLGRDLKNMVYGQENAIDALVAA
VKMSRSGLALPDKPIGSFLFSGPTGVGKTEAAKQLAYSLGVPLQRFDMSEYMERHAVSRLIGAPPGYVGFEQGGLLTEAV
NKQPHCVLLLDEIEKAHPDIFNVLLQVMDAGKLTDNNGKSADFRNVILIMTTNAGAESLSRPSLGFTAKRERGDEMQAIN
KLFTPEFRNRLDAIIPFAPLSEPIIVKVVDKFLLQLEHQLLDKKVEAEFTSALHKYLAEKGFDPQMGARPMHRLIQEKIR
KPLADELLFGKLSDGGFVRIDWDAAKEEAVLKFKKSKVKIKTASA

Nucleotide

• Length: 2298 bp

>NTDB_id=160914 A6L32_RS10910 WP_002221163.1 2102905..2105202(+) (clpC) [Neisseria meningitidis strain M22718]
ATGCTTGCACCCGAATTGGAACAGATTTTGCAGCAGCTTTACCGCGAGGCGCGTAAGGCTCATTATGAATTTATCAGCCT
CGAGCATCTGCTTTTGGTACTCATCGAAGAAGATGCCTCCGTGCCGAACGTCTTAAAACTATGCGGCGCGGATTTGAAAG
TGGTGTCCGAACAGCTCGCCGCCAGCGTTGCCGAAAACACCCCCCTGATTCCCGAACACCTTTTAGACACGGTCGAAACA
CGGCCCACGCTCGGCTTCCAACGCGTGATGCAACGGGCGATGGTGCATACCCAGTCTGCCGGAAAAGCCGCAGTCGAACC
GTTGGACGTTTTGGTCGCGCTGATGAGCGAAACCGACAGCCACACCGTCTATTTCCTCAAGCTGCAATCGGTTACGCGTT
TTGAAGTTTTGCGCTGTATTGCCCACGGCTCTCCCGATGAAGATGAAGATGAAGACGATGGCAACTATTCTTCAGACGGC
ATGGACGACGATAATGAAAACCGCGCCAAACCGGGCAAAAACCCTTTATCGGCGTACACCGTCAACCTCAACGCCGAAGT
CAAAGCCGGCCGTATCGACCCTTTGATTGGTCGCAAACACGAAATGGAACGGCTGGTGCAAATCCTATGCCGCCGCCGCA
AAAACAATCCGCTTTTGGTCGGCGAAGCGGGCGTGGGCAAAACCGCGCTGGCGGAAGGTTTGGCACATCAAATCGTCAAC
GGCGGCATTCCAGACGCGCTCAAAGATGCCGAAGTGTACGCGCTGGATATGGGCTCGCTGTTGGCGGGCACGAAATACCG
CGGCGACTTTGAAGCGCGGGTCAAATCCGTCTTGAAACAGCTCGAAAAAATCCCGCACGCCATTTTGTTTATCGACGAAA
TCCACACCATCATCGGCGCGGGCAGCACCAGCGGCGGCACCATGGACGCGTCCAACCTGCTCAAACCCGCGCTGGCAAAA
GGTTCGCTGCGCTGCATCGGCGCGACCACCTACGACGAATACCGCACCATTTTCGACAAAGACCATGCCTTAAGCCGCCG
CTTCCAAAAAATCGACGTGGTCGAACCCACCGTTTCCGAAACCGTTCAAATCCTGCGCGGCTTGAAACCGATGTTTGAAG
CCTTCCACCAAGTCCGCTACACTCAAGGCGCACTCGAAGCCGCCGCCGAACTCTCCGCACGCTACATCAACGAGCGTTTC
CTGCCCGACAAAGCCATCGACGTAATGGATGAAGCAGGCGCGGCGCAACGGATTCTGCCCAAATCCAAACAGAAAAAAGT
CATCGGCAAAGCACAAATCGAAACCGTCATCGCCAAAGTTTCGCGGATTCCCGAAAAAACCGTGTCGCACGACGACAAAC
AAGTGCTGCAATTCCTCGGTCGCGATTTGAAAAACATGGTTTACGGTCAAGAAAACGCCATCGACGCGCTGGTTGCCGCC
GTCAAAATGTCGCGTTCCGGCCTTGCCCTGCCCGACAAACCGATAGGCAGCTTCCTCTTCTCCGGCCCGACCGGCGTGGG
CAAAACCGAAGCCGCCAAACAGCTTGCCTACTCGCTGGGCGTACCGCTGCAACGCTTTGATATGTCCGAATACATGGAAC
GCCATGCCGTATCGCGCCTCATCGGCGCGCCACCGGGCTACGTCGGCTTTGAACAAGGCGGCCTTTTGACCGAAGCCGTC
AACAAACAGCCGCATTGCGTATTGCTCTTGGACGAAATCGAAAAAGCCCACCCCGACATTTTCAACGTCCTCCTGCAAGT
CATGGACGCAGGCAAACTGACCGACAACAACGGCAAGAGTGCCGATTTCCGCAACGTCATCCTGATTATGACCACCAACG
CAGGCGCGGAAAGCCTCAGCCGCCCCAGCCTCGGCTTTACCGCCAAGCGCGAACGCGGCGACGAAATGCAGGCAATCAAC
AAGCTCTTCACGCCCGAGTTCCGCAACCGCTTGGACGCGATTATCCCGTTTGCACCCTTGTCCGAACCCATCATCGTCAA
AGTCGTGGACAAATTCCTGCTCCAGCTCGAACACCAGCTCCTCGACAAAAAAGTCGAAGCCGAATTCACGTCGGCATTGC
ACAAATATCTGGCGGAAAAAGGTTTCGACCCGCAAATGGGCGCGCGCCCGATGCACCGCCTGATTCAGGAAAAAATCCGC
AAACCGCTCGCCGACGAACTCCTGTTCGGCAAACTATCCGACGGCGGCTTCGTGCGGATAGACTGGGATGCGGCAAAAGA
AGAAGCCGTGTTGAAGTTTAAGAAAAGCAAGGTCAAAATAAAAACCGCCTCCGCGTAA

Domains

Predicted by InterProScan.

• Clp amino terminal domain, pathogenicity island component (Clp_N) (15-61)

• ATPase family associated with various cellular activities (AAA) (AAA) (218-350)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (660-740)

• AAA domain (Cdc48 subfamily) (AAA_2) (493-654)

• AAA lid domain (AAA_lid_9) (358-455)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	38.386	100	0.41
clpC	Bacillus subtilis subsp. subtilis str. 168	37.129	100	0.392
clpA	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	41.609	94.248	0.392