Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   HSISS4_RS02725 Genome accession   NZ_CP013216
Coordinates   556374..557600 (+) Length   408 a.a.
NCBI ID   WP_002890340.1    Uniprot ID   J7SIE0
Organism   Streptococcus salivarius strain HSISS4     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 551374..562600
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HSISS4_RS02705 (HSISS4_00495) - 551799..553070 (-) 1272 WP_021144513.1 hydroxymethylglutaryl-CoA reductase, degradative -
  HSISS4_RS02710 (HSISS4_00496) - 553072..554238 (-) 1167 WP_021144512.1 hydroxymethylglutaryl-CoA synthase -
  HSISS4_RS02715 (HSISS4_00497) - 554710..555570 (+) 861 WP_021144511.1 thymidylate synthase -
  HSISS4_RS02720 (HSISS4_00498) - 555678..556181 (+) 504 WP_021144510.1 dihydrofolate reductase -
  HSISS4_RS10240 (HSISS4_00499) - 556186..556356 (+) 171 WP_002886174.1 hypothetical protein -
  HSISS4_RS02725 (HSISS4_00500) clpX 556374..557600 (+) 1227 WP_002890340.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  HSISS4_RS02730 (HSISS4_00501) yihA 557610..558209 (+) 600 WP_021144508.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  HSISS4_RS02735 (HSISS4_00503) - 558339..559716 (+) 1378 Protein_502 amino acid permease -
  HSISS4_RS02740 (HSISS4_00504) mmuM 559728..560678 (+) 951 WP_021144505.1 homocysteine S-methyltransferase -
  HSISS4_RS02745 (HSISS4_00505) - 560791..561045 (+) 255 WP_021144504.1 DUF1912 family protein -
  HSISS4_RS02750 (HSISS4_00506) - 561120..561497 (+) 378 WP_059749103.1 helix-hairpin-helix domain-containing protein -
  HSISS4_RS02755 (HSISS4_00507) plsY 561615..562256 (-) 642 WP_021144502.1 glycerol-3-phosphate 1-O-acyltransferase PlsY -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 44993.33 Da        Isoelectric Point: 4.3489

>NTDB_id=160698 HSISS4_RS02725 WP_002890340.1 556374..557600(+) (clpX) [Streptococcus salivarius strain HSISS4]
MAGNRNEEMVYCSFCGKNQEEVKKIIAGNGVFICNECVALSQEIIREEMAEEVLADLAETPKPKELLDILNNYVVGQDRA
KRALAVAVYNHYKRINFTESREDNDVDLQKSNILMIGPTGSGKTFLAQTLARSLNVPFAIADATSLTEAGYVGEDVENIL
LKLIQAADFNIERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTKN
ILFIVGGAFDGIEDIVKQRLGEKIIGFGQNNKAIDDDSSYMQEIVAEDIQKFGLIPEFIGRLPVLAALEQLTVDDLVRIL
TEPRNALVKQYQTLLSYDGVELEFDQDALEAIASKAIERKTGARGLRSIIEEVMMDVMFEIPSQEDVTKVRITKEAVDGT
AAPVLETA

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=160698 HSISS4_RS02725 WP_002890340.1 556374..557600(+) (clpX) [Streptococcus salivarius strain HSISS4]
ATGGCTGGAAATCGTAATGAAGAAATGGTTTATTGTTCATTTTGTGGCAAAAACCAAGAAGAAGTAAAGAAAATTATCGC
TGGTAACGGTGTCTTTATCTGTAACGAATGTGTGGCCTTATCACAAGAAATCATTCGTGAGGAAATGGCAGAAGAAGTTT
TGGCTGACTTGGCCGAAACACCAAAGCCAAAAGAACTTTTGGATATTTTGAACAACTATGTCGTGGGGCAAGACCGTGCT
AAACGTGCCTTGGCAGTAGCTGTTTACAACCACTATAAACGTATCAACTTCACAGAAAGTCGTGAAGACAATGATGTGGA
TTTGCAGAAATCAAACATTCTCATGATTGGACCAACAGGTTCAGGGAAGACTTTCTTGGCTCAGACCTTGGCTCGAAGCT
TGAATGTTCCTTTCGCGATTGCGGATGCGACATCATTGACAGAAGCTGGTTATGTGGGTGAGGACGTGGAAAATATCCTC
CTCAAATTGATCCAAGCGGCAGACTTCAATATTGAACGTGCGGAACGTGGAATCATCTATGTCGACGAGATTGATAAGAT
TGCTAAAAAAGGTGAGAATGTTTCAATCACTCGTGACGTTTCAGGTGAAGGGGTTCAACAAGCTCTCTTGAAGATTATTG
AAGGAACAGTAGCTAGTGTTCCCCCTCAAGGTGGCCGTAAGCACCCTAACCAAGAGATGATTCAAATTGATACAAAGAAT
ATTCTCTTTATCGTTGGTGGTGCCTTTGATGGAATCGAAGATATCGTTAAGCAACGTCTTGGTGAGAAAATCATTGGTTT
TGGTCAAAATAATAAGGCTATTGATGATGACTCATCATACATGCAGGAAATTGTGGCTGAAGATATCCAAAAATTTGGTC
TGATCCCTGAGTTTATCGGACGTTTGCCAGTCCTTGCGGCCCTTGAACAGTTAACGGTTGACGACTTGGTTCGTATCTTG
ACAGAGCCTAGAAATGCCTTGGTTAAACAGTATCAAACCCTCTTGTCTTATGATGGGGTTGAACTTGAGTTTGACCAAGA
TGCTCTTGAAGCTATTGCAAGTAAGGCGATTGAACGTAAGACTGGTGCGCGTGGGCTTCGCTCTATCATTGAAGAAGTCA
TGATGGATGTCATGTTTGAAATTCCTAGCCAGGAAGATGTGACTAAGGTTCGTATTACCAAAGAAGCCGTTGACGGTACA
GCTGCTCCAGTTTTGGAAACAGCGTAA

Domains

Predicted by InterproScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-389)

AAA domain (Cdc48 subfamily) (AAA_2)

(109-304)

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-47)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB J7SIE0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

89.976

100

0.902
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

57.606

98.284

0.566

Multiple sequence alignment