Detailed information NTG0160192

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: FORC26_RS13615
• Genome accession: NZ_CP013132
• Coordinates: 2613680..2614567 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143417.1
• Uniprot ID: A0A641A7I7
• Organism: Staphylococcus aureus strain FORC_026
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2608680..2619567

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FORC26_RS13580	-	2608699..2608791 (+)	93	WP_010956583.1	hypothetical protein	-
FORC26_RS13585 (FORC26_2330)	-	2608899..2609396 (-)	498	WP_001065268.1	glutathione peroxidase	-
FORC26_RS13590	-	2609406..2609666 (-)	261	WP_001791974.1	hypothetical protein	-
FORC26_RS14255	-	2610048..2610161 (-)	114	Protein_2472	hypothetical protein	-
FORC26_RS13605 (FORC26_2331)	-	2610820..2612820 (-)	2001	WP_000776740.1	ABC transporter permease	-
FORC26_RS13610 (FORC26_2332)	-	2612817..2613572 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
FORC26_RS13615 (FORC26_2333)	braS	2613680..2614567 (-)	888	WP_000143417.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
FORC26_RS13620 (FORC26_2334)	braR	2614578..2615243 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
FORC26_RS13625 (FORC26_2335)	-	2615269..2615469 (-)	201	WP_000604727.1	hypothetical protein	-
FORC26_RS13635 (FORC26_2336)	-	2615667..2617091 (+)	1425	WP_000953748.1	alkaline phosphatase	-
FORC26_RS14620	-	2617151..2617252 (-)	102	WP_000731972.1	SE2200 family small protein	-
FORC26_RS13645 (FORC26_2337)	-	2617374..2617829 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
FORC26_RS13650 (FORC26_2338)	-	2618074..2618835 (-)	762	WP_000323441.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34027.28 Da
• Isoelectric Point: 5.8962

>NTDB_id=160192 FORC26_RS13615 WP_000143417.1 2613680..2614567(-) (braS) [Staphylococcus aureus strain FORC_026]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLLIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=160192 FORC26_RS13615 WP_000143417.1 2613680..2614567(-) (braS) [Staphylococcus aureus strain FORC_026]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTACTGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (192-294)

3D structure

• AlphaFold DB: A0A641A7I7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	98.983	100	0.99