Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   BBD27_RS07290 Genome accession   NZ_CP016394
Coordinates   1373636..1374280 (+) Length   214 a.a.
NCBI ID   WP_002951384.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain ND07     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1368636..1379280
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BBD27_RS07275 (BBD27_1435) stkP/pknB 1369010..1370881 (+) 1872 WP_024703938.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  BBD27_RS11525 (BBD27_1437) - 1371519..1371686 (+) 168 WP_014608530.1 potassium channel family protein -
  BBD27_RS07280 (BBD27_1438) liaF 1371941..1372639 (+) 699 WP_011226289.1 cell wall-active antibiotics response protein LiaF -
  BBD27_RS07285 (BBD27_1439) - 1372636..1373646 (+) 1011 WP_011226288.1 sensor histidine kinase -
  BBD27_RS07290 (BBD27_1440) vraR 1373636..1374280 (+) 645 WP_002951384.1 response regulator transcription factor Regulator
  BBD27_RS07305 (BBD27_1441) rimM 1374952..1375470 (+) 519 WP_011226286.1 ribosome maturation factor RimM -
  BBD27_RS07310 (BBD27_1442) trmD 1375460..1376179 (+) 720 WP_024703937.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  BBD27_RS07315 (BBD27_1443) - 1376181..1377179 (+) 999 WP_014608529.1 NAD(P)/FAD-dependent oxidoreductase -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24048.39 Da        Isoelectric Point: 4.5864

>NTDB_id=160027 BBD27_RS07290 WP_002951384.1 1373636..1374280(+) (vraR) [Streptococcus thermophilus strain ND07]
MSNKINVILVDDHEMVRLGLKSFLNLQGDVEVVGEAENGREGVDLALELRPDVVVMDLVMPELDGVQATLELLKEWPEAK
ILVLTSYLDNEKIYPVIEAGAKGYMLKTSSAAEILNSIRKVYRGEEAIETEVDNKIKYHDSHPNLHDDLTARERDILALL
AKGYDNQTIANELFISLKTVKTHVSNILGKLNVDDRTQAVVYAFRHHLVSQDDE

Nucleotide


Download         Length: 645 bp        

>NTDB_id=160027 BBD27_RS07290 WP_002951384.1 1373636..1374280(+) (vraR) [Streptococcus thermophilus strain ND07]
ATGTCGAATAAGATTAATGTAATTTTGGTAGATGATCATGAAATGGTTCGTTTAGGCCTTAAGAGTTTCTTGAATCTCCA
AGGAGATGTAGAAGTGGTTGGAGAGGCAGAAAACGGCCGTGAGGGTGTCGATCTTGCCCTGGAGCTACGACCAGATGTCG
TTGTTATGGACCTTGTTATGCCTGAGCTAGATGGTGTTCAGGCGACTTTGGAATTGCTAAAAGAATGGCCTGAAGCTAAG
ATTCTAGTTTTGACCAGCTATTTGGACAATGAAAAAATTTATCCAGTCATTGAAGCTGGCGCCAAAGGCTATATGCTTAA
AACGAGCAGTGCAGCAGAGATTCTAAATAGTATCCGTAAGGTTTACCGTGGAGAGGAAGCTATCGAAACTGAGGTAGACA
ATAAGATTAAATACCATGATAGTCACCCGAACTTACATGATGACTTGACCGCGCGCGAACGTGATATCTTAGCCCTCCTA
GCTAAAGGCTATGACAATCAAACCATTGCTAACGAACTTTTTATTTCTTTAAAAACCGTCAAGACTCATGTGTCTAATAT
CCTTGGGAAATTAAATGTTGATGACCGTACTCAGGCTGTAGTTTATGCCTTTAGACATCATCTGGTTTCACAGGATGATG
AATAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(7-118)

Bacterial regulatory proteins, luxR family (GerE)

(149-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

50.485

96.262

0.486
  degU Bacillus subtilis subsp. subtilis str. 168

36.161

100

0.379