Detailed information    

insolico Bioinformatically predicted

Overview

Name   hapR   Type   Regulator
Locus tag   NH62_RS05945 Genome accession   NZ_CP012998
Coordinates   103240..103851 (-) Length   203 a.a.
NCBI ID   WP_000340100.1    Uniprot ID   Q4F6W7
Organism   Vibrio cholerae strain 2012Env-9     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 98240..108851
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NH62_RS05920 (NH62_20105) - 98765..99334 (-) 570 WP_000836325.1 BON domain-containing protein -
  NH62_RS05925 (NH62_20106) - 99337..99927 (-) 591 WP_000887295.1 phosphoheptose isomerase -
  NH62_RS05930 (NH62_20107) - 99931..100299 (-) 369 WP_001893625.1 YraN family protein -
  NH62_RS05935 (NH62_20108) - 100286..102091 (-) 1806 WP_001015477.1 penicillin-binding protein activator -
  NH62_RS05940 (NH62_20109) rsmI 102161..103027 (+) 867 WP_000131549.1 16S rRNA (cytidine(1402)-2'-O)-methyltransferase -
  NH62_RS05945 (NH62_20110) hapR 103240..103851 (-) 612 WP_000340100.1 quorum-sensing master transcriptional regulator HapR Regulator
  NH62_RS05950 (NH62_20111) hpt 104147..104680 (+) 534 WP_000683351.1 hypoxanthine phosphoribosyltransferase -
  NH62_RS05955 (NH62_20112) can 104755..105423 (-) 669 WP_001114116.1 carbonate dehydratase -
  NH62_RS05960 (NH62_20113) - 105571..107217 (+) 1647 WP_000484915.1 SulP family inorganic anion transporter -
  NH62_RS05965 (NH62_20114) - 107598..108515 (+) 918 WP_000271066.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 203 a.a.        Molecular weight: 23720.44 Da        Isoelectric Point: 6.6356

>NTDB_id=159026 NH62_RS05945 WP_000340100.1 103240..103851(-) (hapR) [Vibrio cholerae strain 2012Env-9]
MDASIEKRPRTRLSPQKRKLQLMEIALEVFAKRGIGRGGHADIAEIAQVSVATVFNYFPTREDLVDDVLNFVVRQYSNFL
TDHIDLDLDVKTNLQTLCKEMVKLAMTDCHWLKVWFEWSASTRDEVWPLFVSTNRTNQLLIRNMFMKAMERGELCEKHDV
DNMASLFHGIFYSIFLQVNRLGEQEAVYKLVDSYLNMLCIYKN

Nucleotide


Download         Length: 612 bp        

>NTDB_id=159026 NH62_RS05945 WP_000340100.1 103240..103851(-) (hapR) [Vibrio cholerae strain 2012Env-9]
ATGGACGCATCAATCGAAAAACGCCCTCGAACTCGGCTATCGCCTCAAAAACGCAAACTACAACTGATGGAAATCGCGTT
GGAAGTGTTTGCTAAACGCGGCATTGGTCGTGGTGGTCACGCAGATATTGCCGAGATTGCGCAAGTCTCCGTTGCAACAG
TGTTCAACTACTTCCCAACTCGTGAAGACCTGGTTGACGATGTGCTGAATTTTGTGGTTCGTCAGTACTCCAATTTTTTG
ACCGATCACATCGATCTTGATTTGGATGTGAAAACCAACCTACAAACTCTGTGCAAAGAGATGGTGAAATTGGCGATGAC
CGATTGTCACTGGCTCAAAGTCTGGTTTGAGTGGAGTGCTTCAACCCGTGACGAAGTTTGGCCACTGTTTGTTTCCACCA
ACCGAACTAACCAACTGCTGATCAGAAACATGTTTATGAAAGCGATGGAACGTGGCGAATTGTGTGAGAAACACGATGTC
GATAACATGGCCAGCCTGTTCCACGGCATCTTCTACTCCATCTTCTTACAAGTGAACCGTTTAGGTGAACAAGAAGCAGT
GTATAAGTTGGTCGATAGCTACCTCAATATGCTGTGTATCTATAAGAACTAG

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, tetR family (TetR_N)

(23-67)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q4F6W7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hapR Vibrio cholerae C6706

99.507

100

0.995
  hapR Vibrio cholerae strain A1552

99.507

100

0.995
  opaR Vibrio parahaemolyticus RIMD 2210633

72.727

97.537

0.709

Multiple sequence alignment