Detailed information NTG0158921

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: SAST40_RS12900
• Genome accession: NZ_CP012979
• Coordinates: 2579070..2579957 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143417.1
• Uniprot ID: A0A641A7I7
• Organism: Staphylococcus aureus strain ST20130940
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2574070..2584957

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SAST40_RS12865	-	2574089..2574181 (+)	93	WP_010956583.1	hypothetical protein	-
SAST40_RS12870 (SAST40_02640)	-	2574289..2574786 (-)	498	WP_001065268.1	glutathione peroxidase	-
SAST40_RS12875	-	2574796..2575056 (-)	261	WP_001791974.1	hypothetical protein	-
SAST40_RS12880	-	2575438..2575551 (-)	114	Protein_2449	hypothetical protein	-
SAST40_RS12890 (SAST40_03634)	-	2576210..2578210 (-)	2001	WP_000776740.1	ABC transporter permease	-
SAST40_RS12895 (SAST40_03635)	-	2578207..2578962 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
SAST40_RS12900 (SAST40_04061)	braS	2579070..2579957 (-)	888	WP_000143417.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
SAST40_RS12905 (SAST40_02644)	braR	2579968..2580633 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
SAST40_RS12910 (SAST40_03637)	-	2580659..2580859 (-)	201	WP_000604727.1	hypothetical protein	-
SAST40_RS12920 (SAST40_04062)	-	2581057..2582481 (+)	1425	WP_000953748.1	alkaline phosphatase	-
SAST40_RS14480 (SAST40_04063)	-	2582541..2582642 (-)	102	WP_000731972.1	SE2200 family small protein	-
SAST40_RS12925 (SAST40_04064)	-	2582764..2583219 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
SAST40_RS12930 (SAST40_02649)	-	2583464..2584225 (-)	762	WP_000323441.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34027.28 Da
• Isoelectric Point: 5.8962

>NTDB_id=158921 SAST40_RS12900 WP_000143417.1 2579070..2579957(-) (braS) [Staphylococcus aureus strain ST20130940]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLLIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=158921 SAST40_RS12900 WP_000143417.1 2579070..2579957(-) (braS) [Staphylococcus aureus strain ST20130940]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTACTGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (192-294)

3D structure

• AlphaFold DB: A0A641A7I7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	98.983	100	0.99