Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   SAST40_RS02460 Genome accession   NZ_CP012979
Coordinates   518876..519445 (+) Length   189 a.a.
NCBI ID   WP_062909912.1    Uniprot ID   -
Organism   Staphylococcus aureus strain ST20130940     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 513876..524445
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SAST40_RS02435 (SAST40_03177) cysE 515089..515736 (+) 648 WP_001805237.1 serine O-acetyltransferase -
  SAST40_RS02440 (SAST40_00495) cysS 515720..517120 (+) 1401 WP_000631963.1 cysteine--tRNA ligase -
  SAST40_RS02445 (SAST40_00496) - 517113..517517 (+) 405 WP_000370182.1 Mini-ribonuclease 3 -
  SAST40_RS02450 (SAST40_00497) rlmB 517525..518271 (+) 747 WP_000390332.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  SAST40_RS02455 (SAST40_00498) - 518271..518795 (+) 525 WP_000664738.1 NYN domain-containing protein -
  SAST40_RS02460 (SAST40_00499) sigH 518876..519445 (+) 570 WP_062909912.1 sigma-70 family RNA polymerase sigma factor Regulator
  SAST40_RS13595 rpmG 519560..519703 (+) 144 WP_001788193.1 50S ribosomal protein L33 -
  SAST40_RS02465 (SAST40_03020) secE 519759..519941 (+) 183 WP_001074473.1 preprotein translocase subunit SecE -
  SAST40_RS02470 (SAST40_00501) nusG 519954..520502 (+) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  SAST40_RS02475 (SAST40_00502) rplK 520683..521105 (+) 423 WP_001085792.1 50S ribosomal protein L11 -
  SAST40_RS02480 (SAST40_00503) rplA 521313..522005 (+) 693 WP_001074619.1 50S ribosomal protein L1 -
  SAST40_RS02485 (SAST40_00504) rplJ 522277..522777 (+) 501 WP_001273085.1 50S ribosomal protein L10 -
  SAST40_RS02490 (SAST40_00505) rplL 522820..523188 (+) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  SAST40_RS02495 (SAST40_00506) - 523363..523971 (+) 609 WP_000020304.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 22975.86 Da        Isoelectric Point: 9.1603

>NTDB_id=158886 SAST40_RS02460 WP_062909912.1 518876..519445(+) (sigH) [Staphylococcus aureus strain ST20130940]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGEQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRFDVENNYLNKLAIKELICQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKCYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=158886 SAST40_RS02460 WP_062909912.1 518876..519445(+) (sigH) [Staphylococcus aureus strain ST20130940]
TTGAAATACGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAGAGCAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTTTGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTTGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAATTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAATGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus N315

98.942

100

0.989
  sigH Staphylococcus aureus MW2

97.884

100

0.979

Multiple sequence alignment