Detailed information NTG0158710

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: SAST39_RS09685
• Genome accession: NZ_CP012970
• Coordinates: 1938350..1939393 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain ST20130939
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1933350..1944393

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SAST39_RS09655 (SAST39_03387)	-	1933772..1935028 (-)	1257	WP_072419726.1	aminopeptidase	-
SAST39_RS09660 (SAST39_01956)	-	1935031..1935231 (-)	201	WP_000180460.1	DUF1128 family protein	-
SAST39_RS09665 (SAST39_01957)	-	1935378..1935842 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
SAST39_RS09670 (SAST39_01958)	-	1935849..1936124 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
SAST39_RS09675 (SAST39_01960)	-	1936402..1937619 (+)	1218	WP_000037079.1	YihY/virulence factor BrkB family protein	-
SAST39_RS09680 (SAST39_03388)	vraR	1937731..1938360 (-)	630	WP_000153536.1	two-component system response regulator VraR	Regulator
SAST39_RS09685 (SAST39_01962)	vraS	1938350..1939393 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
SAST39_RS09690 (SAST39_03389)	liaF	1939390..1940091 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
SAST39_RS09695 (SAST39_01964)	-	1940106..1940492 (-)	387	WP_001110179.1	hypothetical protein	-
SAST39_RS09700 (SAST39_01965)	map	1940709..1941467 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
SAST39_RS09710 (SAST39_01966)	-	1941997..1942983 (+)	987	WP_000999713.1	FUSC family protein	-
SAST39_RS09715 (SAST39_02910)	-	1943473..1943886 (-)	414	WP_001566709.1	hypothetical protein	-
SAST39_RS09720 (SAST39_04229)	-	1943915..1944025 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=158710 SAST39_RS09685 WP_001017131.1 1938350..1939393(-) (vraS) [Staphylococcus aureus strain ST20130939]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=158710 SAST39_RS09685 WP_001017131.1 1938350..1939393(-) (vraS) [Staphylococcus aureus strain ST20130939]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTAATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGCATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTGGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGTTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCGATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1