Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   SAST39_RS10110 Genome accession   NZ_CP012970
Coordinates   2017407..2018123 (+) Length   238 a.a.
NCBI ID   WP_000688498.1    Uniprot ID   Q2VG52
Organism   Staphylococcus aureus strain ST20130939     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2012407..2023123
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SAST39_RS10080 (SAST39_02038) - 2012625..2013251 (+) 627 WP_000522384.1 nitroreductase family protein -
  SAST39_RS10085 (SAST39_02040) - 2013612..2014397 (+) 786 WP_000867950.1 carbon-nitrogen family hydrolase -
  SAST39_RS14775 (SAST39_02041) hld 2014997..2015077 (-) 81 WP_000046022.1 delta-hemolysin -
  SAST39_RS10095 (SAST39_03404) - 2015313..2015948 (+) 636 WP_001641623.1 accessory gene regulator AgrB -
  SAST39_RS10100 (SAST39_03405) agrD 2015932..2016075 (+) 144 WP_001094921.1 cyclic lactone autoinducer peptide AgrD -
  SAST39_RS10105 (SAST39_03406) agrC 2016105..2017388 (+) 1284 WP_000447888.1 quorum-sensing sensor histidine kinase AgrC -
  SAST39_RS10110 (SAST39_03407) agrA 2017407..2018123 (+) 717 WP_000688498.1 quorum-sensing response regulator AgrA Regulator
  SAST39_RS10115 - 2018195..2018304 (+) 110 Protein_1921 hypothetical protein -
  SAST39_RS10120 (SAST39_02047) - 2018492..2019451 (-) 960 WP_001253291.1 carbohydrate kinase family protein -
  SAST39_RS10125 (SAST39_02048) - 2019448..2020932 (-) 1485 WP_000141411.1 sucrose-6-phosphate hydrolase -
  SAST39_RS10130 (SAST39_02049) - 2021081..2022031 (-) 951 WP_000790329.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27933.91 Da        Isoelectric Point: 6.0927

>NTDB_id=158711 SAST39_RS10110 WP_000688498.1 2017407..2018123(+) (agrA) [Staphylococcus aureus strain ST20130939]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSRDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=158711 SAST39_RS10110 WP_000688498.1 2017407..2018123(+) (agrA) [Staphylococcus aureus strain ST20130939]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGTTTACAATTAT
TATCAAGAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q2VG52

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.58

100

0.996

Multiple sequence alignment