Detailed information NTG0158600

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: ACT75_RS04305
• Genome accession: NZ_CP012959
• Coordinates: 898379..899497 (-)
• Length: 372 a.a.
• NCBI ID: WP_005540807.1
• Uniprot ID: A0A142FZH0
• Organism: Aggregatibacter actinomycetemcomitans strain 624
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 893379..904497

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACT75_RS04290 (ACT75_04285)	rlmB	894497..895234 (+)	738	WP_005540800.1	23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB	-
ACT75_RS04295 (ACT75_04290)	glpT	895567..897009 (+)	1443	WP_005540804.1	glycerol-3-phosphate transporter	-
ACT75_RS04300 (ACT75_04295)	glpQ	897241..898323 (+)	1083	WP_005540806.1	glycerophosphodiester phosphodiesterase	-
ACT75_RS04305 (ACT75_04300)	dprA	898379..899497 (-)	1119	WP_005540807.1	DNA-processing protein DprA	Machinery gene
ACT75_RS04310 (ACT75_04305)	rplI	899715..900164 (-)	450	WP_005549026.1	50S ribosomal protein L9	-
ACT75_RS04315 (ACT75_04310)	rpsR	900180..900410 (-)	231	WP_005541294.1	30S ribosomal protein S18	-
ACT75_RS04320 (ACT75_04315)	priB	900423..900749 (-)	327	WP_005549024.1	primosomal replication protein N	-
ACT75_RS04325 (ACT75_04320)	rpsF	900736..901113 (-)	378	WP_005541284.1	30S ribosomal protein S6	-
ACT75_RS04330 (ACT75_04325)	lexA	901265..901888 (-)	624	WP_005541282.1	transcriptional repressor LexA	-

Sequence

Protein

• Length: 372 a.a.
• Molecular weight: 41696.85 Da
• Isoelectric Point: 6.4278

>NTDB_id=158600 ACT75_RS04305 WP_005540807.1 898379..899497(-) (dprA) [Aggregatibacter actinomycetemcomitans strain 624]
MNKHLALLLRLLQIPKLGPTTIHKILAQVNLSELQYYDAAAFTQMGWNAQQIQAWFHPEQRYIEPALLWGEKEGNHILDY
FHPDYPELLKQIESAPPVLFVKGATSALSQQQIAIVGSRQCSSYGEYWAKYFATELTTNGFIITSGLALGIDGFCHQAAV
DLKQPTIAVLGSGLEEVYPAKHRKLAQNIIEHDGALVSEFFPLQPPIAENFPRRNRIISGLSLATLIIEATERSGSLITA
RYALEQNREIFALPGNIQSQFSQGCHKLIKQGAMLVENVEDILENLAPQMTWKKRPQNRPHFSAIRKTTSTSLPPPVTPS
HPELYNIIGYNPISADDLSTTLNLSIDQILIQLLELELQDLIISENGLYRRV

Nucleotide

• Length: 1119 bp

>NTDB_id=158600 ACT75_RS04305 WP_005540807.1 898379..899497(-) (dprA) [Aggregatibacter actinomycetemcomitans strain 624]
ATGAACAAACATTTAGCACTTTTACTGCGCCTATTACAAATCCCCAAATTAGGCCCCACCACAATCCATAAAATCCTTGC
TCAAGTGAATTTATCCGAATTGCAATATTACGACGCGGCTGCATTTACGCAAATGGGCTGGAACGCACAACAGATTCAAG
CATGGTTTCATCCGGAGCAGCGCTATATTGAACCGGCACTTTTATGGGGAGAGAAAGAAGGAAATCATATTCTTGATTAT
TTTCACCCTGATTATCCCGAATTATTAAAACAAATCGAAAGCGCACCGCCGGTATTGTTCGTCAAAGGCGCGACAAGTGC
GCTATCACAGCAACAAATCGCTATTGTCGGTAGCCGCCAATGTTCAAGTTATGGTGAATATTGGGCGAAATATTTTGCCA
CGGAATTAACCACCAACGGTTTCATCATTACCAGCGGGTTGGCGTTAGGCATTGATGGTTTCTGCCATCAGGCTGCGGTC
GATTTAAAACAACCGACCATCGCCGTTTTAGGCAGCGGACTGGAAGAAGTGTATCCCGCCAAACATCGCAAATTAGCGCA
GAATATTATTGAACATGATGGTGCGTTGGTTTCTGAATTTTTCCCGCTACAACCACCGATTGCCGAAAATTTTCCCCGCC
GCAATCGCATTATCAGCGGGTTATCATTAGCGACCTTAATTATTGAAGCCACCGAACGCAGCGGATCATTAATTACGGCA
CGCTATGCGTTAGAACAAAACAGAGAAATTTTTGCACTACCGGGCAATATTCAAAGCCAGTTCAGCCAAGGCTGCCATAA
GCTTATTAAACAAGGCGCAATGCTGGTCGAAAACGTGGAAGATATTTTAGAAAATCTTGCGCCACAAATGACATGGAAAA
AACGCCCGCAAAATCGACCGCACTTTTCCGCTATAAGGAAAACAACGTCCACCTCATTACCGCCTCCCGTCACGCCATCC
CACCCCGAGCTATACAATATTATTGGTTATAACCCGATAAGCGCAGATGATTTATCTACAACACTTAATCTGTCTATTGA
TCAAATTCTCATTCAATTGCTGGAGCTGGAATTACAGGATTTAATTATCAGTGAAAACGGATTATATCGGCGGGTTTGA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (71-277)

• DprA winged helix domain (DprA_WH) (311-365)

3D structure

• AlphaFold DB: A0A142FZH0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Haemophilus influenzae Rd KW20	63.564	100	0.642
dprA	Glaesserella parasuis strain SC1401	55.966	94.624	0.53
dprA	Vibrio campbellii strain DS40M4	44.293	98.925	0.438
dprA	Vibrio cholerae strain A1552	43.316	100	0.435
dprA	Legionella pneumophila strain ERS1305867	40.541	99.462	0.403