Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   SanJ4211_RS07420 Genome accession   NZ_CP012805
Coordinates   1472730..1473419 (-) Length   229 a.a.
NCBI ID   WP_057489790.1    Uniprot ID   A0AAP6ENS5
Organism   Streptococcus anginosus strain J4211     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1467730..1478419
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SanJ4211_RS07400 (SanJ4211_1474c) nrdR 1468196..1468669 (-) 474 WP_003029936.1 transcriptional regulator NrdR -
  SanJ4211_RS07405 (SanJ4211_1475) - 1468836..1469450 (+) 615 WP_057489788.1 hypothetical protein -
  SanJ4211_RS07410 (SanJ4211_1476c) - 1469497..1470312 (-) 816 WP_057489789.1 endonuclease/exonuclease/phosphatase family protein -
  SanJ4211_RS07415 (SanJ4211_1477c) - 1470329..1472518 (-) 2190 WP_049516785.1 PTS transporter subunit IIBC -
  SanJ4211_RS07420 (SanJ4211_1479c) covR 1472730..1473419 (-) 690 WP_057489790.1 response regulator transcription factor Regulator
  SanJ4211_RS07425 (SanJ4211_1480c) gndA 1473428..1474852 (-) 1425 WP_021001983.1 NADP-dependent phosphogluconate dehydrogenase -
  SanJ4211_RS07430 (SanJ4211_1481c) - 1475151..1475774 (-) 624 WP_049516783.1 DNA alkylation repair protein -
  SanJ4211_RS07435 (SanJ4211_1482c) - 1475824..1476360 (-) 537 WP_049516782.1 DUF177 domain-containing protein -
  SanJ4211_RS07440 - 1476473..1477329 (+) 857 Protein_1456 XRE family transcriptional regulator -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26516.65 Da        Isoelectric Point: 6.2732

>NTDB_id=157714 SanJ4211_RS07420 WP_057489790.1 1472730..1473419(-) (covR) [Streptococcus anginosus strain J4211]
MAKRILLVEKEKKLAQFIGLELQKEGYRVDLFETGKDALASARANQYDLFLLNFMLDDMTGTEFAAQLSVIKLASVIIVL
DNRDNILQYTEEIQRFAVAYMVEPFIVTDLVEKISAIFRGRDFIDQHCSQMKVPTSYRNLRIDVQNHTVYRGEEVIALTR
REYDLLATLMGSHQALSREQLLERVWKYEGAVETNVVDVYIRYLRSKIDIVGQKSYIKTVRGVGYVMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=157714 SanJ4211_RS07420 WP_057489790.1 1472730..1473419(-) (covR) [Streptococcus anginosus strain J4211]
ATGGCGAAGCGGATTTTATTAGTTGAGAAAGAAAAAAAATTAGCGCAATTTATTGGCTTAGAATTACAAAAAGAAGGTTA
TCGAGTTGATCTTTTTGAAACAGGAAAAGATGCTTTGGCGTCTGCGAGAGCTAATCAATACGATTTATTCCTGTTGAATT
TTATGCTTGACGATATGACAGGAACAGAATTTGCCGCACAATTAAGTGTGATAAAGCTTGCTTCGGTCATCATTGTATTG
GATAATCGTGATAATATTCTTCAATATACTGAGGAAATCCAACGCTTTGCTGTTGCTTACATGGTAGAACCATTCATTGT
GACGGACTTAGTTGAAAAAATTTCTGCCATTTTTCGTGGGCGTGATTTTATTGACCAGCATTGTAGTCAGATGAAAGTTC
CAACATCTTATCGGAATCTTCGGATTGATGTGCAAAATCATACAGTTTATCGAGGTGAAGAAGTGATTGCTTTGACTCGA
AGAGAGTATGATTTATTAGCAACATTGATGGGAAGTCATCAGGCTTTAAGCCGTGAACAGTTGTTAGAACGCGTGTGGAA
ATACGAAGGAGCTGTTGAAACAAATGTTGTCGATGTTTATATTCGCTATCTTCGTAGTAAAATTGATATAGTGGGGCAAA
AAAGTTATATAAAAACCGTGCGTGGTGTTGGTTATGTTATGCAAGAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.696

100

0.489
  covR Lactococcus lactis subsp. lactis strain DGCC12653

45.852

100

0.459

Multiple sequence alignment