Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   ACH32_RS06585 Genome accession   NZ_CP012756
Coordinates   1246016..1246681 (-) Length   221 a.a.
NCBI ID   WP_000697881.1    Uniprot ID   -
Organism   Staphylococcus aureus strain JS395     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1241016..1251681
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACH32_RS06560 (ACH32_06555) - 1241470..1241583 (-) 114 WP_072468803.1 hypothetical protein -
  ACH32_RS06570 (ACH32_06565) - 1242258..1244258 (-) 2001 WP_000776736.1 ABC transporter permease -
  ACH32_RS06575 (ACH32_06570) - 1244255..1245010 (-) 756 WP_000923765.1 ABC transporter ATP-binding protein -
  ACH32_RS06580 (ACH32_06575) braS 1245118..1246005 (-) 888 WP_060649710.1 nisin susceptibility-associated two-component system sensor histidine kinase NsaS Regulator
  ACH32_RS06585 (ACH32_06580) braR 1246016..1246681 (-) 666 WP_000697881.1 nisin susceptibility-associated two-component system response regulator NsaR Regulator
  ACH32_RS06590 (ACH32_06585) - 1246707..1246907 (-) 201 WP_000604722.1 hypothetical protein -
  ACH32_RS06600 (ACH32_06595) - 1247105..1248528 (+) 1424 Protein_1256 alkaline phosphatase -
  ACH32_RS15720 - 1248588..1248689 (-) 102 WP_000731972.1 SE2200 family small protein -
  ACH32_RS06605 (ACH32_06600) - 1248811..1249266 (-) 456 WP_060649711.1 MarR family winged helix-turn-helix transcriptional regulator -
  ACH32_RS06610 (ACH32_06605) - 1249511..1250272 (-) 762 WP_000323454.1 alpha/beta hydrolase -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 25391.44 Da        Isoelectric Point: 4.7961

>NTDB_id=157616 ACH32_RS06585 WP_000697881.1 1246016..1246681(-) (braR) [Staphylococcus aureus strain JS395]
MKILIVEDDFVIAESLASELKKWNYGVIVVEQFDDILSIFNQHQPQLVLLDINLPTLNGFHWCQEIRKTSNVPIIFISSR
IDNMDQIMAIQMGGDDFIEKPFNLSLTIAKIQALLRRTYDLSVANDSMTVKGCTLILDEAKVGYQEQNIQLSLTELQILK
LLFQNEDKYVSRTALIEKCWESENFIDDNTLAVNMTRLRKKLNTIGVNDFIITKKNVGYKV

Nucleotide


Download         Length: 666 bp        

>NTDB_id=157616 ACH32_RS06585 WP_000697881.1 1246016..1246681(-) (braR) [Staphylococcus aureus strain JS395]
ATGAAAATATTAATTGTTGAAGATGATTTTGTTATAGCAGAAAGTTTAGCATCTGAACTTAAAAAATGGAATTACGGTGT
TATTGTCGTTGAACAATTTGATGATATACTGTCTATCTTTAACCAACATCAACCTCAGCTTGTATTGCTAGATATTAATT
TACCAACGTTAAATGGTTTTCATTGGTGTCAAGAAATCCGAAAAACATCTAATGTGCCAATTATATTTATTAGTTCCCGT
ATTGATAATATGGACCAAATTATGGCAATACAAATGGGGGGAGATGATTTTATCGAAAAACCATTTAACTTGTCATTAAC
GATTGCCAAAATTCAAGCATTATTGAGACGAACTTATGACTTGTCAGTAGCTAATGATTCGATGACGGTTAAAGGTTGTA
CATTAATATTAGATGAAGCAAAAGTCGGGTATCAAGAACAAAACATACAGCTATCTTTGACTGAATTACAAATATTAAAG
TTATTATTTCAAAATGAAGATAAATATGTAAGTAGAACTGCTTTAATTGAAAAATGTTGGGAATCAGAAAACTTCATAGA
TGATAACACATTAGCTGTTAACATGACGCGTCTGCGTAAAAAATTAAATACTATTGGCGTTAATGATTTTATCATTACAA
AGAAAAATGTCGGATATAAAGTATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-111)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

99.095

100

0.991

Multiple sequence alignment