Detailed information NTG0157615

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: ACH32_RS06580
• Genome accession: NZ_CP012756
• Coordinates: 1245118..1246005 (-)
• Length: 295 a.a.
• NCBI ID: WP_060649710.1
• Uniprot ID: -
• Organism: Staphylococcus aureus strain JS395
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1240118..1251005

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACH32_RS06545 (ACH32_06540)	-	1240125..1240213 (+)	89	Protein_1247	hypothetical protein	-
ACH32_RS06550 (ACH32_06545)	-	1240321..1240818 (-)	498	WP_001065267.1	glutathione peroxidase	-
ACH32_RS06555 (ACH32_06550)	-	1240828..1241088 (-)	261	WP_072468805.1	hypothetical protein	-
ACH32_RS06560 (ACH32_06555)	-	1241470..1241583 (-)	114	WP_072468803.1	hypothetical protein	-
ACH32_RS06570 (ACH32_06565)	-	1242258..1244258 (-)	2001	WP_000776736.1	ABC transporter permease	-
ACH32_RS06575 (ACH32_06570)	-	1244255..1245010 (-)	756	WP_000923765.1	ABC transporter ATP-binding protein	-
ACH32_RS06580 (ACH32_06575)	braS	1245118..1246005 (-)	888	WP_060649710.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
ACH32_RS06585 (ACH32_06580)	braR	1246016..1246681 (-)	666	WP_000697881.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
ACH32_RS06590 (ACH32_06585)	-	1246707..1246907 (-)	201	WP_000604722.1	hypothetical protein	-
ACH32_RS06600 (ACH32_06595)	-	1247105..1248528 (+)	1424	Protein_1256	alkaline phosphatase	-
ACH32_RS15720	-	1248588..1248689 (-)	102	WP_000731972.1	SE2200 family small protein	-
ACH32_RS06605 (ACH32_06600)	-	1248811..1249266 (-)	456	WP_060649711.1	MarR family winged helix-turn-helix transcriptional regulator	-
ACH32_RS06610 (ACH32_06605)	-	1249511..1250272 (-)	762	WP_000323454.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34047.25 Da
• Isoelectric Point: 5.6141

>NTDB_id=157615 ACH32_RS06580 WP_060649710.1 1245118..1246005(-) (braS) [Staphylococcus aureus strain JS395]
MTFLKSITQEIAIVIVIFALFGSMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKDDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSTGIGLFIVKQISNHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=157615 ACH32_RS06580 WP_060649710.1 1245118..1246005(-) (braS) [Staphylococcus aureus strain JS395]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTCAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAGATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCGAATGTTGTGAATCGTGTTCGTCAAGAGGTAATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATAAACAATATTATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGAATCGGTATTAGTGAGGCAGACTTACCTAAA
ATATTCGACAAAGGTTATTCGGGGTATAATGGACAACGTCAAAGTAATTCAACTGGGATTGGCTTATTTATTGTAAAGCA
AATTTCAAATCACACTAATCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	97.966	100	0.98