Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   SanJ4206_RS07220 Genome accession   NZ_CP012719
Coordinates   1491611..1492300 (-) Length   229 a.a.
NCBI ID   WP_003029931.1    Uniprot ID   A0AAI9NHY7
Organism   Streptococcus anginosus strain J4206     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1486611..1497300
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SanJ4206_RS07200 (SanJ4206_1400c) nrdR 1487081..1487554 (-) 474 WP_003029936.1 transcriptional regulator NrdR -
  SanJ4206_RS07205 (SanJ4206_1401) - 1487721..1488332 (+) 612 WP_022525076.1 hypothetical protein -
  SanJ4206_RS07210 (SanJ4206_1402c) - 1488379..1489194 (-) 816 WP_003029933.1 endonuclease/exonuclease/phosphatase family protein -
  SanJ4206_RS07215 (SanJ4206_1403c) - 1489211..1491400 (-) 2190 WP_003029932.1 PTS transporter subunit IIBC -
  SanJ4206_RS07220 (SanJ4206_1404c) covR 1491611..1492300 (-) 690 WP_003029931.1 response regulator transcription factor Regulator
  SanJ4206_RS07225 (SanJ4206_1405c) gndA 1492309..1493733 (-) 1425 WP_003029930.1 NADP-dependent phosphogluconate dehydrogenase -
  SanJ4206_RS07230 (SanJ4206_1406) - 1493938..1494603 (+) 666 WP_003029929.1 TetR/AcrR family transcriptional regulator -
  SanJ4206_RS07235 (SanJ4206_1407) - 1494593..1495327 (+) 735 WP_003029928.1 ABC transporter ATP-binding protein -
  SanJ4206_RS07240 (SanJ4206_1408) - 1495311..1496039 (+) 729 WP_003029927.1 ABC transporter permease -
  SanJ4206_RS07245 (SanJ4206_1409) - 1496039..1496266 (+) 228 WP_003029926.1 hypothetical protein -
  SanJ4206_RS07250 (SanJ4206_1410c) - 1496389..1496928 (-) 540 WP_003029925.1 DUF177 domain-containing protein -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26495.59 Da        Isoelectric Point: 6.5011

>NTDB_id=156788 SanJ4206_RS07220 WP_003029931.1 1491611..1492300(-) (covR) [Streptococcus anginosus strain J4206]
MAKRILLVEKEKKLAQFIGLELQKEGYRVDLFETGKDALASARANQYDLFLLNFMLDDMTGTEFAAQLSVIKPASVIIVL
DHRDNILQYTEEIQRFAVAYMVEPFIVTDLVEKISAIFRGRDFIDQHCSQMKVPTSYRNLRIDVQNHTVYRGEEVIALTR
REYDLLATLMGSHQALSREQLLERVWKYEGAVETNVVDVYIRYLRSKIDIVGQKSYIKTVRGVGYAMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=156788 SanJ4206_RS07220 WP_003029931.1 1491611..1492300(-) (covR) [Streptococcus anginosus strain J4206]
ATGGCGAAGCGGATTTTATTAGTTGAGAAAGAAAAAAAGTTAGCACAATTTATTGGCTTAGAACTACAAAAAGAAGGTTA
TCGAGTTGATCTTTTTGAAACAGGAAAAGATGCTTTAGCGTCTGCGCGAGCGAATCAATACGATTTATTCCTGTTGAATT
TTATGCTTGACGATATGACAGGAACAGAATTTGCTGCACAATTAAGTGTGATAAAGCCTGCTTCGGTCATCATTGTATTG
GATCATCGTGACAATATTCTACAATATACTGAGGAAATCCAACGCTTTGCTGTTGCTTACATGGTAGAACCATTCATTGT
GACGGACTTAGTTGAAAAAATTTCTGCCATTTTTCGTGGACGTGATTTTATTGATCAGCATTGTAGTCAGATGAAAGTTC
CAACATCTTATCGGAATCTTCGGATTGATGTGCAAAATCATACAGTTTATCGAGGTGAAGAAGTGATTGCTTTGACTCGA
CGAGAATATGATTTATTAGCAACATTGATGGGAAGCCATCAAGCTTTAAGCCGTGAACAGCTGTTAGAGCGCGTGTGGAA
ATATGAAGGAGCTGTTGAAACAAATGTTGTTGATGTTTATATTCGCTATCTTCGTAGTAAAATTGATATAGTGGGGCAAA
AAAGTTATATAAAAACCGTGCGTGGTGTTGGTTATGCTATGCAAGAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.261

100

0.485
  covR Lactococcus lactis subsp. lactis strain DGCC12653

45.415

100

0.454

Multiple sequence alignment