Detailed information NTG0156755

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: SanJ4206_RS01105
• Genome accession: NZ_CP012719
• Coordinates: 217146..219278 (+)
• Length: 710 a.a.
• NCBI ID: WP_022525288.1
• Uniprot ID: A0AAI9NH90
• Organism: Streptococcus anginosus strain J4206
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 212146..224278

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SanJ4206_RS01090 (SanJ4206_0180)	comYH	212306..213259 (+)	954	WP_003028478.1	class I SAM-dependent methyltransferase	Machinery gene
SanJ4206_RS01095 (SanJ4206_0181)	-	213306..214505 (+)	1200	WP_003028479.1	acetate kinase	-
SanJ4206_RS01100 (SanJ4206_0182)	glmS	214894..216708 (+)	1815	WP_003028480.1	glutamine--fructose-6-phosphate transaminase (isomerizing)	-
SanJ4206_RS01105 (SanJ4206_0184)	clpC	217146..219278 (+)	2133	WP_022525288.1	AAA family ATPase	Regulator
SanJ4206_RS01110 (SanJ4206_0186)	-	219475..220932 (+)	1458	WP_003028488.1	PTS ascorbate transporter subunit IIC	-
SanJ4206_RS01115 (SanJ4206_0187)	-	220963..221244 (+)	282	WP_003028490.1	PTS sugar transporter subunit IIB	-
SanJ4206_RS01120 (SanJ4206_0188)	-	221431..221916 (+)	486	WP_006269994.1	PTS sugar transporter subunit IIA	-
SanJ4206_RS01125 (SanJ4206_0189)	-	221964..222629 (+)	666	WP_003032302.1	3-keto-L-gulonate-6-phosphate decarboxylase UlaD	-
SanJ4206_RS01130 (SanJ4206_0190)	-	222633..223502 (+)	870	WP_022525287.1	L-ribulose-5-phosphate 3-epimerase	-
SanJ4206_RS01135 (SanJ4206_0191)	-	223496..224197 (+)	702	WP_003028497.1	L-ribulose-5-phosphate 4-epimerase	-

Sequence

Protein

• Length: 710 a.a.
• Molecular weight: 78732.69 Da
• Isoelectric Point: 4.6520

>NTDB_id=156755 SanJ4206_RS01105 WP_022525288.1 217146..219278(+) (clpC) [Streptococcus anginosus strain J4206]
MNNNYNNFDNMDDLFNQLMGRMGGFNSENRRYLINGREVTPEEFAQYRATGKLPKQAMEAQNPQMQTQTGNPKQDGILAK
LGRNLTEEARQDMLDPVIGRNKEIQETAEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISVDIS
GLEAGTQYRGSFEENIQNLVSEVKEAGNVILFFDEIHQILGAGSTGGDSGSKGLADILKPALSRGDLTVIGATTQDEYRN
TILKNAALARRFNEVKVNAPSAEDTYKILQGIRDLYEKHHNVILPDEVLKAAVDYSIQYIPQRSLPDKAIDLVDVTAAHL
AAQHPVTDVHAVEREIAEQKAKQEAAVEKEDFETALNAKMRIEELEKKIENHTEDMKVTATVNDVAESVERMTGIPVSQM
GSSDIERLKEMNARLKTKVIGQNEAVEAVARAIRRNRAGFDEGNRPIGSFLFVGPTGVGKTELAKQLALDMFGTKDAIIR
LDMSEYSDRTAVSKLIGTTAGYVGYDDNSNTLTERVRRNPYSIILLDEIEKADSQVITLLLQVLDDGRLTDGQGNTVNFK
NTVIIATSNAGFGYESFTGDEEKDMKIMDRLKPYFRPEFLNRFNAVIEFSHLGKEDLAEIVELMLDEVNQTLAKKDITLT
VTDAAKAYLAEEGYDEVMGVRPLRRVIEQQIRDKVTDYHLDHLDVKHLLADLKDDELVIEEATDDSATKA

Nucleotide

• Length: 2133 bp

>NTDB_id=156755 SanJ4206_RS01105 WP_022525288.1 217146..219278(+) (clpC) [Streptococcus anginosus strain J4206]
ATGAACAACAACTACAACAACTTTGATAACATGGATGATCTTTTCAATCAATTGATGGGAAGAATGGGCGGTTTTAATAG
TGAAAATCGGCGTTATCTCATCAATGGACGTGAAGTAACACCAGAGGAATTTGCACAATACCGTGCAACGGGAAAACTTC
CGAAACAGGCAATGGAGGCTCAAAATCCACAAATGCAAACGCAAACAGGCAATCCAAAACAAGATGGCATTTTAGCAAAA
TTGGGTCGCAATTTGACAGAGGAAGCGCGTCAAGATATGCTAGATCCCGTCATTGGACGTAACAAGGAAATTCAAGAAAC
AGCAGAAATTCTGTCTCGTCGGACGAAAAACAATCCAGTTCTAGTCGGAGATGCTGGAGTTGGTAAGACTGCAGTTGTTG
AAGGTTTGGCGCAGGCGATTGTTAATGGTGATGTTCCTGCTGCTATTAAGAATAAAGAAATTATTTCTGTAGATATTTCG
GGATTAGAAGCAGGTACACAGTATCGTGGTAGCTTTGAAGAAAATATTCAAAATTTGGTTTCTGAAGTAAAAGAAGCGGG
CAATGTTATTCTCTTCTTTGATGAAATTCATCAAATCCTCGGTGCTGGAAGCACAGGTGGAGATAGTGGCTCTAAAGGTT
TGGCGGATATTTTGAAACCAGCCCTTTCTCGCGGGGATTTAACGGTGATTGGTGCGACAACGCAAGATGAATACCGCAAC
ACCATTTTGAAAAATGCAGCTCTGGCTCGTCGTTTCAATGAAGTAAAGGTAAATGCTCCTTCTGCAGAAGATACTTATAA
GATTTTGCAAGGAATTCGTGATTTGTACGAAAAACACCACAATGTTATCTTGCCAGATGAAGTGTTAAAAGCAGCTGTGG
ATTATTCGATTCAATATATTCCGCAACGCAGTTTGCCAGATAAAGCGATTGACCTAGTGGATGTGACAGCAGCTCACTTG
GCAGCTCAACACCCTGTTACAGACGTACACGCCGTGGAACGTGAAATCGCAGAGCAAAAGGCCAAACAAGAAGCTGCAGT
TGAAAAAGAAGATTTTGAAACGGCTTTGAATGCTAAGATGCGCATTGAAGAGCTGGAAAAGAAAATTGAAAATCATACAG
AAGACATGAAAGTGACAGCAACTGTCAATGATGTGGCAGAGTCTGTAGAACGCATGACGGGTATTCCTGTTTCCCAAATG
GGCAGCAGCGATATTGAGCGCTTGAAAGAGATGAATGCGCGCCTGAAAACAAAAGTCATCGGACAAAATGAAGCAGTTGA
AGCGGTGGCGCGTGCTATTCGGAGAAATCGTGCAGGTTTTGATGAAGGCAATCGTCCGATTGGTAGCTTCCTCTTTGTCG
GACCAACTGGTGTCGGAAAAACAGAGCTAGCTAAGCAATTAGCGCTTGATATGTTTGGTACAAAAGACGCGATTATCCGT
TTGGATATGTCTGAATACTCTGACCGTACAGCTGTGTCGAAGCTGATTGGTACAACAGCTGGTTATGTGGGATATGATGA
CAACAGCAATACCTTGACAGAACGTGTTCGTCGCAATCCATACTCGATCATTTTGCTGGACGAAATCGAAAAAGCTGATT
CGCAAGTCATCACGCTGTTACTACAAGTCTTAGATGATGGGCGTTTGACAGATGGACAAGGAAATACTGTCAATTTTAAG
AATACGGTTATTATTGCTACTTCTAACGCAGGATTTGGCTATGAAAGCTTTACAGGTGACGAAGAAAAAGATATGAAAAT
TATGGATCGATTGAAACCATACTTCCGTCCAGAATTCTTGAATCGGTTCAATGCAGTTATTGAATTCTCACACCTTGGTA
AAGAAGACTTGGCTGAAATTGTTGAATTGATGCTAGATGAAGTCAACCAAACGCTTGCTAAGAAAGACATCACTCTGACG
GTAACGGATGCCGCAAAAGCTTACCTAGCAGAAGAAGGTTACGATGAAGTCATGGGTGTTCGTCCGCTTCGCCGTGTGAT
TGAACAACAAATCCGTGACAAAGTAACCGACTATCATCTGGATCATTTGGATGTAAAACATCTCTTAGCTGACCTTAAAG
ATGATGAATTAGTCATTGAGGAAGCAACAGATGATTCAGCTACAAAAGCATAA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (612-681)

• AAA domain (Cdc48 subfamily) (AAA_2) (445-605)

• ATPase family associated with various cellular activities (AAA) (AAA) (120-252)

• AAA lid domain (AAA_lid_9) (261-355)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Lactococcus lactis subsp. cremoris KW2	47.893	100	0.48
clpE	Streptococcus mutans UA159	48.62	91.831	0.446
clpE	Streptococcus pneumoniae Rx1	48.657	89.155	0.434
clpE	Streptococcus pneumoniae D39	48.657	89.155	0.434
clpE	Streptococcus pneumoniae R6	48.657	89.155	0.434
clpE	Streptococcus pneumoniae TIGR4	48.413	88.732	0.43
clpC	Bacillus subtilis subsp. subtilis str. 168	46.594	90.986	0.424
clpC	Streptococcus pneumoniae D39	43.218	89.296	0.386
clpC	Streptococcus pneumoniae Rx1	43.218	89.296	0.386
clpC	Streptococcus pneumoniae TIGR4	43.06	89.296	0.385
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	43.78	87.183	0.382
clpC	Streptococcus thermophilus LMG 18311	42.429	89.296	0.379
clpC	Streptococcus mutans UA159	43.178	87.746	0.379
clpC	Streptococcus thermophilus LMD-9	41.875	90.141	0.377