Detailed information NTG0156607

Bioinformatically predicted

Overview

• Name: dsbA1
• Type: Machinery gene
• Locus tag: AN159_RS07445
• Genome accession: NZ_CP012694
• Coordinates: 1415139..1415837 (-)
• Length: 232 a.a.
• NCBI ID: WP_002215673.1
• Uniprot ID: A0A0U1RKJ4
• Organism: Neisseria meningitidis strain 331401
• Function: DNA binding and uptake; interact with PilQ (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1410139..1420837

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AN159_RS07430 (AN159_07475)	-	1410452..1411495 (-)	1044	WP_069972474.1	peptidylprolyl isomerase	-
AN159_RS07435 (AN159_07480)	-	1411600..1414008 (-)	2409	WP_069972475.1	LPS-assembly protein LptD	-
AN159_RS07440 (AN159_07485)	amgK	1414078..1415082 (+)	1005	WP_002215675.1	N-acetylmuramate/N-acetylglucosamine kinase AmgK	-
AN159_RS07445 (AN159_07490)	dsbA1	1415139..1415837 (-)	699	WP_002215673.1	thiol:disulfide interchange protein DsbA/DsbL	Machinery gene
AN159_RS14830	-	1416131..1416238 (-)	108	Protein_1395	IS5/IS1182 family transposase	-
AN159_RS07450 (AN159_07495)	murJ	1416296..1417834 (+)	1539	WP_069972476.1	murein biosynthesis integral membrane protein MurJ	-
AN159_RS07455 (AN159_07500)	-	1417967..1418923 (+)	957	WP_002236650.1	YheT family hydrolase	-
AN159_RS07460 (AN159_07505)	trpC	1418974..1419756 (+)	783	WP_069972477.1	indole-3-glycerol phosphate synthase TrpC	-

Sequence

Protein

• Length: 232 a.a.
• Molecular weight: 25245.84 Da
• Isoelectric Point: 5.6016

>NTDB_id=156607 AN159_RS07445 WP_002215673.1 1415139..1415837(-) (dsbA1) [Neisseria meningitidis strain 331401]
MKSKHLALGVAALFALAACDSKVQTSVPADSAPAASAAAAPAGLVEGQNYTVLANPIPQQQAGKVEVLEFFGYFCPHCAH
LEPVLSKHAKSFKDDMYLRTEHVVWQKEMLTLARLAAAVDMAAADSKDVANSHIFDAMVNQKIKLQEPEVLKKWLGEQTA
FDGKKVLAAYESPESQARADKMQELTETFQIDGTPTVIVGGKYKVEFADWESGMNTIDLLADKVREEQKAAH

Nucleotide

• Length: 699 bp

>NTDB_id=156607 AN159_RS07445 WP_002215673.1 1415139..1415837(-) (dsbA1) [Neisseria meningitidis strain 331401]
ATGAAATCCAAACACCTCGCCCTCGGCGTTGCCGCCCTGTTCGCACTTGCCGCGTGCGACAGCAAAGTCCAAACCAGCGT
CCCCGCCGACAGCGCGCCTGCCGCTTCGGCAGCCGCCGCCCCGGCAGGGCTGGTCGAAGGGCAAAACTATACTGTCCTTG
CCAACCCGATTCCCCAACAGCAGGCAGGCAAAGTCGAAGTCCTTGAGTTTTTCGGCTATTTCTGTCCGCACTGCGCCCAC
CTCGAACCTGTTTTAAGCAAACACGCCAAGTCTTTTAAAGACGATATGTACCTGCGTACCGAACACGTCGTCTGGCAGAA
AGAAATGCTGACGCTCGCACGCCTCGCCGCCGCCGTCGATATGGCTGCCGCCGACAGCAAAGATGTGGCGAACAGCCATA
TTTTCGATGCGATGGTCAACCAAAAAATCAAGCTGCAAGAGCCGGAAGTCCTCAAAAAATGGCTGGGCGAACAAACCGCC
TTTGACGGCAAAAAAGTCCTTGCCGCTTACGAATCTCCCGAAAGCCAGGCGCGCGCCGACAAAATGCAGGAGCTGACCGA
AACCTTCCAAATCGACGGTACGCCCACGGTTATCGTCGGCGGCAAATATAAAGTCGAATTTGCCGACTGGGAGTCCGGTA
TGAACACCATCGACCTTTTGGCGGACAAAGTACGCGAAGAACAAAAAGCCGCGCACTAA

Domains

Predicted by InterproScan.

• Thioredoxin (Thioredoxin_4) (63-212)

3D structure

• AlphaFold DB: A0A0U1RKJ4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dsbA1	Neisseria meningitidis MC58	98.707	100	0.987
dsbA2	Neisseria meningitidis MC58	76.882	80.172	0.616