Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   RN86_RS00590 Genome accession   NZ_CP012648
Coordinates   114873..115562 (-) Length   229 a.a.
NCBI ID   WP_012000010.1    Uniprot ID   A0AAP2NYS9
Organism   Streptococcus gordonii strain KCOM 1506 (= ChDC B679)     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 109873..120562
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RN86_RS00570 (RN86_00565) - 110345..110779 (+) 435 WP_046165199.1 hypothetical protein -
  RN86_RS00575 (RN86_00570) - 110929..111345 (+) 417 WP_046165112.1 hypothetical protein -
  RN86_RS00580 (RN86_00575) - 111488..112303 (-) 816 WP_046165111.1 endonuclease/exonuclease/phosphatase family protein -
  RN86_RS00585 (RN86_00580) - 112321..114513 (-) 2193 WP_046165110.1 PTS transporter subunit IIBC -
  RN86_RS00590 (RN86_00585) covR 114873..115562 (-) 690 WP_012000010.1 response regulator transcription factor Regulator
  RN86_RS00595 (RN86_00590) gndA 115575..116999 (-) 1425 WP_008808507.1 NADP-dependent phosphogluconate dehydrogenase -
  RN86_RS00600 (RN86_00595) - 117135..118616 (-) 1482 WP_008808506.1 flotillin family protein -
  RN86_RS00605 (RN86_00600) - 118718..119248 (-) 531 WP_045505786.1 DUF177 domain-containing protein -
  RN86_RS00610 (RN86_00605) - 119347..120216 (+) 870 WP_046165109.1 Rgg/GadR/MutR family transcriptional regulator -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26261.28 Da        Isoelectric Point: 5.1919

>NTDB_id=156052 RN86_RS00590 WP_012000010.1 114873..115562(-) (covR) [Streptococcus gordonii strain KCOM 1506 (= ChDC B679)]
MAKRILLVENEKNLARFIMLELQKESYQVDLAETGQEGLALAKENDYDLLLLNNQFADGTAFAFAQQLSLLKPAAVIIVM
VSREEIADSAEEIQQFAVSYMVKPFIISDLVDKISAIFRGRDFIDQKCSQLKVPTAYRNLRVDLKNHTVYRGEEIIALTR
REYDLLVTLMSSNKVMSREQLLDRVWKYESASETNIVDVYIRYLRSKIDLPGQESYIKTVRGIGYSMQG

Nucleotide


Download         Length: 690 bp        

>NTDB_id=156052 RN86_RS00590 WP_012000010.1 114873..115562(-) (covR) [Streptococcus gordonii strain KCOM 1506 (= ChDC B679)]
ATGGCGAAGCGGATTTTATTAGTTGAAAATGAAAAGAATCTAGCACGATTTATCATGCTGGAATTACAAAAGGAAAGTTA
TCAAGTAGACCTAGCGGAAACAGGGCAAGAGGGACTAGCTCTAGCAAAGGAAAACGATTATGATTTACTTTTACTAAATA
ATCAGTTTGCTGATGGAACAGCCTTTGCCTTTGCTCAACAATTAAGTTTATTAAAACCAGCTGCAGTAATCATTGTAATG
GTGAGCCGAGAGGAGATTGCGGATTCGGCTGAAGAGATTCAGCAGTTTGCAGTTTCTTATATGGTAAAACCCTTTATTAT
TAGTGATCTGGTTGATAAAATATCTGCTATTTTTCGTGGACGAGATTTTATTGATCAGAAATGTAGCCAGTTAAAAGTTC
CTACTGCTTATCGTAATTTGCGGGTTGATTTGAAAAATCATACGGTTTATCGAGGGGAAGAAATTATTGCTTTGACGAGA
CGAGAGTACGATTTACTAGTGACTCTAATGAGCAGTAATAAGGTGATGAGCCGTGAGCAACTGTTAGATCGAGTGTGGAA
GTATGAAAGTGCATCTGAGACTAATATAGTGGATGTATATATTCGTTACCTCCGTAGTAAAATCGATCTTCCAGGACAAG
AAAGTTATATTAAAACCGTTCGTGGAATTGGTTATTCCATGCAGGGTTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

51.77

98.69

0.511
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.737

99.563

0.445

Multiple sequence alignment