Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   RN80_RS03690 Genome accession   NZ_CP012646
Coordinates   722295..722984 (+) Length   229 a.a.
NCBI ID   WP_060627580.1    Uniprot ID   A0AAX0NAH4
Organism   Streptococcus mitis strain KCOM 1350 (= ChDC B183)     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 717295..727984
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RN80_RS03665 (RN80_03675) gpsB 717373..717702 (+) 330 WP_060627571.1 cell division regulator GpsB -
  RN80_RS03675 (RN80_03685) - 718188..719345 (+) 1158 WP_060627573.1 THUMP domain-containing class I SAM-dependent RNA methyltransferase -
  RN80_RS03680 (RN80_03690) mapZ 719359..720783 (+) 1425 WP_060627575.1 cell division site-positioning protein MapZ -
  RN80_RS03685 (RN80_03695) gndA 720859..722283 (+) 1425 WP_060627577.1 NADP-dependent phosphogluconate dehydrogenase -
  RN80_RS03690 (RN80_03700) covR 722295..722984 (+) 690 WP_060627580.1 response regulator transcription factor Regulator
  RN80_RS03695 (RN80_03705) - 723083..724000 (+) 918 WP_060627582.1 N-acetylmuramoyl-L-alanine amidase family protein -
  RN80_RS03700 (RN80_03710) mvk 724228..725106 (+) 879 WP_060627584.1 mevalonate kinase -
  RN80_RS03705 (RN80_03715) mvaD 725088..726041 (+) 954 WP_060627587.1 diphosphomevalonate decarboxylase -
  RN80_RS03710 (RN80_03720) - 726028..727035 (+) 1008 WP_060627589.1 phosphomevalonate kinase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26813.92 Da        Isoelectric Point: 8.0270

>NTDB_id=156011 RN80_RS03690 WP_060627580.1 722295..722984(+) (covR) [Streptococcus mitis strain KCOM 1350 (= ChDC B183)]
MGKRILLLEKERNLAHFLSLELQKEQYRVDQVEEGQKALSMALQTDYDLILLNARLGDMTAQDFADRLSRTKPASVIMVL
DHREELQDQLETIQRFAVSYIYKPVIIDNLVARISAIFRGRDFIDQHCSQMKVPTSYRNLRMDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=156011 RN80_RS03690 WP_060627580.1 722295..722984(+) (covR) [Streptococcus mitis strain KCOM 1350 (= ChDC B183)]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAAAAAGAGCAATA
CCGAGTTGATCAGGTTGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGACTTGATTTTATTGAATG
CTCGTCTGGGGGATATGACAGCCCAGGATTTTGCAGATAGGCTGAGTCGGACTAAGCCAGCTTCAGTCATCATGGTCTTG
GATCATCGTGAAGAATTGCAAGACCAGCTTGAGACAATCCAACGCTTTGCCGTTTCTTACATCTATAAGCCAGTAATTAT
TGATAATCTGGTAGCTCGTATTTCAGCGATTTTCCGAGGTCGGGACTTCATCGACCAACACTGTAGTCAGATGAAGGTTC
CAACATCTTACCGCAATTTGCGTATGGATGTAGAACATCATACCGTTTATCGTGGCGAGGAGATGATTGCTCTGACTCGT
CGTGAGTATGACCTTTTGGCTACTCTTATGGGAAGCAAGAAAGTTCTGACTCGTGAGCAGTTGTTGGAAAGTGTCTGGAA
GTATGAAAGTGCGACCGAAACGAATATCGTGGATGTCTATATCCGTTATCTACGTAGCAAGCTGGATGTAAAAGGTCAGA
AAAGCTACATTAAAACCGTGCGTGGTGTCGGTTACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

49.13

100

0.493
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.93

99.563

0.467

Multiple sequence alignment