Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Machinery gene
Locus tag   ACS15_RS10780 Genome accession   NZ_CP012605
Coordinates   2288306..2290828 (-) Length   840 a.a.
NCBI ID   WP_031329131.1    Uniprot ID   -
Organism   Ralstonia insidiosa strain FC1138     
Function   DNA uptake (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 2288306..2310570 2288306..2290828 within 0


Gene organization within MGE regions


Location: 2288306..2310570
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACS15_RS10780 (ACS15_2281) comA 2288306..2290828 (-) 2523 WP_031329131.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  ACS15_RS10785 (ACS15_2282) - 2290838..2291650 (-) 813 WP_021194069.1 TatD family hydrolase -
  ACS15_RS28010 (ACS15_2283) - 2291750..2292076 (+) 327 WP_021194068.1 DUF2845 domain-containing protein -
  ACS15_RS10795 (ACS15_2284) lolD 2292100..2292828 (-) 729 WP_021194067.1 lipoprotein-releasing ABC transporter ATP-binding protein LolD -
  ACS15_RS10800 (ACS15_2285) - 2292833..2294083 (-) 1251 WP_021194066.1 lipoprotein-releasing ABC transporter permease subunit -
  ACS15_RS10805 (ACS15_2286) - 2294182..2295273 (+) 1092 WP_031329130.1 hypothetical protein -
  ACS15_RS10810 (ACS15_2287) recJ 2295274..2296968 (+) 1695 WP_021194064.1 single-stranded-DNA-specific exonuclease RecJ -
  ACS15_RS10815 (ACS15_2289) fdxA 2297139..2297465 (+) 327 WP_021194063.1 ferredoxin FdxA -
  ACS15_RS10830 (ACS15_2292) - 2298020..2299015 (+) 996 WP_064496234.1 tyrosine-type recombinase/integrase -
  ACS15_RS10835 (ACS15_2293) istA 2299083..2300609 (+) 1527 WP_012760797.1 IS21 family transposase -
  ACS15_RS10840 (ACS15_2294) istB 2300599..2301384 (+) 786 WP_004630242.1 IS21-like element helper ATPase IstB -
  ACS15_RS10845 (ACS15_2295) - 2301461..2302309 (-) 849 WP_310722459.1 IS3 family transposase -
  ACS15_RS29205 - 2302258..2302620 (-) 363 WP_004630237.1 transposase -
  ACS15_RS10855 (ACS15_2297) - 2302797..2303717 (+) 921 WP_342447396.1 RNA-directed DNA polymerase -
  ACS15_RS10860 (ACS15_2298) - 2303714..2304238 (+) 525 WP_021195268.1 hypothetical protein -
  ACS15_RS10865 (ACS15_2299) - 2304231..2304722 (+) 492 WP_021195269.1 DUF1643 domain-containing protein -
  ACS15_RS10875 (ACS15_2300) - 2305101..2305835 (-) 735 WP_021195271.1 thioredoxin family protein -
  ACS15_RS10880 (ACS15_2301) - 2305992..2307098 (-) 1107 WP_021195272.1 YeiH family protein -
  ACS15_RS10885 (ACS15_2303) - 2307191..2308102 (+) 912 WP_031329465.1 LysR family transcriptional regulator -
  ACS15_RS10895 (ACS15_2305) - 2308263..2309324 (-) 1062 WP_021195274.1 site-specific integrase -
  ACS15_RS10900 (ACS15_2306) - 2309533..2310570 (-) 1038 WP_021195275.1 AAA family ATPase -

Sequence

Protein


Download         Length: 840 a.a.        Molecular weight: 90793.19 Da        Isoelectric Point: 8.6978

>NTDB_id=155728 ACS15_RS10780 WP_031329131.1 2288306..2290828(-) (comA) [Ralstonia insidiosa strain FC1138]
MRLGLVGFVAGCMALQMQAVLMPAWQAVVVLWLCLLLAFVARRKPILLSVLLVTSASVAGFGWSDWRAQQRFSVVLSPAW
EGKDIIATGVVAELPQVSEDATRFLFQIESSDAGDAVPSRVRLSWYGARTWGGAGDEGVEPDRRAGIPDLQPGQRWKLTL
RLKRPHSLSNPGGFDGEYAMLADDIRATGYVRTGKRAQNIALGEAEAGFGINVERWRAAVRRHILAALPDARYAPVIVAL
VVGDQSGIAREDWELFRRTGISHLVSISGLHITMIAGLFAAFWMALWRRSFGLARWLRMPLPLRMPTPRAGAIAAMLAAF
GYCLLAGMGVPAQRTLLMLSTVAIARLTDRNVPASLSLCWAAAVVVAVDPWAVMSAGFWLSFGAVAIIFMAAQMVLDGRR
DRETERWWMRYQHGIASSTRIQFAVTFGLLPLTLLLFQQTSVVSAAANGLAIPVVSFLTTPLALVGAALPDPLAQPVLAL
SEVSFRWLVVWLEWLARPSWSVWVAPVAPAWALLLATGGVALLLVPGAHRAWAWRAQGALLLVPMVLARVPVPLPGEFRV
VAFDIGQGAAALVETANHRLLFDTGPRYGDHADAAARVITPYLRGHGIEALDALVVSHEDSDHAGGTETVIDAVPVRTML
ASLPNGHALHATAAAHDIGLTSCLAGQVWTWDGVTFEMLHPARPPADGARVSSNARSCVLRIGNGRHAALLTGDIEAPQE
AALVASETPERLMADILLVPHHGSKTSSSGAFLDAVSPQVAVFQVGYRNRYGHPHRQVWQRYVARDIERLRTDQTGAVVI
ETRGDALEVQTARSMRPRYWSSALEVEALATAADGIDALP

Nucleotide


Download         Length: 2523 bp        

>NTDB_id=155728 ACS15_RS10780 WP_031329131.1 2288306..2290828(-) (comA) [Ralstonia insidiosa strain FC1138]
ATGCGGTTGGGGCTGGTTGGGTTCGTTGCGGGGTGCATGGCGCTGCAGATGCAGGCCGTGCTCATGCCTGCGTGGCAAGC
GGTTGTGGTGCTGTGGCTATGTCTGCTGCTTGCCTTTGTGGCGCGTCGCAAACCGATTCTGCTCTCTGTCCTGCTGGTCA
CCAGTGCTTCCGTTGCTGGCTTTGGCTGGAGCGACTGGCGCGCGCAACAGCGATTTTCTGTCGTGCTCAGCCCGGCGTGG
GAGGGCAAGGACATCATCGCGACTGGCGTGGTGGCCGAACTTCCGCAGGTCTCCGAAGACGCTACGCGCTTTCTCTTTCA
AATCGAATCCAGCGATGCCGGCGATGCCGTGCCATCGCGCGTACGTCTTTCCTGGTACGGCGCTCGCACCTGGGGCGGGG
CGGGTGATGAGGGCGTCGAGCCTGATCGCCGCGCCGGCATCCCCGACCTGCAGCCTGGCCAACGTTGGAAACTGACGCTG
CGGCTCAAACGCCCGCATAGCCTGTCCAACCCGGGCGGCTTCGATGGCGAATACGCGATGCTCGCCGACGACATCCGCGC
CACCGGCTACGTGCGCACCGGCAAGCGCGCACAGAACATCGCGCTGGGCGAGGCCGAGGCAGGCTTCGGCATCAACGTAG
AGCGTTGGCGTGCTGCCGTGCGGCGCCACATCCTCGCGGCATTGCCCGACGCGCGGTATGCGCCTGTCATCGTCGCGCTT
GTGGTGGGCGACCAGAGTGGCATAGCCCGTGAAGATTGGGAGTTGTTCCGCCGTACTGGCATCAGCCATCTCGTCAGCAT
CTCCGGTTTGCACATCACGATGATTGCTGGGTTGTTTGCCGCGTTCTGGATGGCACTGTGGCGACGTTCGTTCGGGCTGG
CGCGCTGGCTGCGCATGCCGTTACCGTTGCGCATGCCGACACCGCGAGCGGGAGCCATTGCAGCCATGCTGGCGGCCTTC
GGCTATTGCCTGCTCGCGGGGATGGGGGTTCCCGCGCAACGCACGCTGCTGATGTTGTCGACTGTCGCGATTGCGCGGCT
GACCGATCGCAACGTGCCGGCAAGCCTGTCGCTGTGCTGGGCAGCGGCCGTGGTGGTGGCGGTGGACCCGTGGGCGGTTA
TGTCGGCGGGCTTCTGGCTCTCGTTTGGCGCGGTCGCGATCATCTTTATGGCCGCGCAGATGGTGCTCGATGGTCGACGT
GATCGCGAGACGGAACGTTGGTGGATGCGTTACCAGCATGGGATTGCCAGTTCCACGCGCATCCAGTTTGCCGTCACGTT
TGGCCTGCTGCCGTTGACGTTGCTGCTGTTCCAGCAGACATCGGTGGTCTCGGCAGCGGCCAATGGATTGGCGATTCCGG
TGGTCAGCTTTTTGACGACACCGCTAGCACTGGTTGGCGCAGCGTTGCCCGATCCGTTGGCCCAGCCAGTGTTGGCACTG
TCCGAGGTGAGCTTTCGCTGGTTGGTGGTGTGGCTTGAGTGGTTGGCGCGGCCAAGCTGGTCGGTTTGGGTTGCGCCAGT
CGCCCCTGCGTGGGCCTTGCTGCTGGCAACGGGCGGCGTGGCTTTGCTGTTGGTGCCGGGTGCCCATCGCGCGTGGGCAT
GGCGCGCGCAGGGCGCATTGCTGCTCGTGCCGATGGTGCTGGCACGTGTTCCGGTGCCGTTGCCGGGCGAGTTTCGCGTT
GTCGCGTTCGACATTGGTCAGGGTGCCGCCGCGCTCGTTGAAACAGCCAACCATCGCCTCCTGTTCGACACCGGCCCACG
CTACGGTGACCACGCTGATGCGGCCGCCCGCGTCATCACACCCTATCTGCGTGGGCATGGCATTGAAGCCCTGGATGCGC
TGGTCGTCAGCCACGAAGACAGTGATCACGCCGGTGGCACCGAAACGGTGATCGACGCGGTGCCGGTACGCACCATGTTG
GCGTCTCTGCCAAACGGACATGCACTACACGCGACGGCCGCCGCGCACGATATCGGCCTGACGAGCTGCTTGGCTGGGCA
AGTATGGACGTGGGACGGCGTGACGTTCGAGATGCTCCACCCGGCGCGGCCGCCCGCCGACGGTGCGCGTGTATCGAGCA
ACGCCCGCAGTTGTGTGCTGCGCATCGGCAACGGCCGGCATGCGGCGCTGTTGACCGGCGACATTGAGGCCCCCCAGGAG
GCCGCGTTGGTGGCCAGCGAAACCCCGGAGCGGCTGATGGCAGACATCTTGCTAGTACCCCATCACGGCAGCAAGACAAG
CTCCAGCGGTGCGTTTTTGGACGCAGTGTCACCGCAGGTGGCGGTTTTCCAGGTCGGCTACCGCAACCGGTACGGACATC
CGCACCGCCAAGTGTGGCAGCGCTATGTGGCGCGCGACATCGAGCGGCTGCGGACCGACCAGACCGGCGCCGTCGTCATC
GAGACGCGCGGCGATGCGCTGGAGGTGCAGACGGCACGGTCGATGCGGCCGCGCTACTGGTCCTCCGCGCTGGAAGTGGA
AGCCCTGGCGACAGCCGCAGACGGAATTGATGCGCTGCCGTAA

Domains

Predicted by InterproScan.

Competence protein (Competence)

(240-525)

Domain of unknown function (DUF4131) (DUF4131)

(24-194)

Metallo-beta-lactamase superfamily (Lactamase_B)

(566-762)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Ralstonia pseudosolanacearum GMI1000

74.498

100

0.751

Multiple sequence alignment