Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   A7B19_RS43665 Genome accession   NZ_CP015726
Coordinates   10261630..10262340 (+) Length   236 a.a.
NCBI ID   WP_063736443.1    Uniprot ID   -
Organism   Streptomyces sp. RTd22     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 10256630..10267340
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A7B19_RS43640 - 10257728..10258663 (-) 936 WP_063736449.1 GntR family transcriptional regulator -
  A7B19_RS43645 - 10258729..10259025 (-) 297 WP_063736447.1 antibiotic biosynthesis monooxygenase family protein -
  A7B19_RS43650 - 10259022..10259507 (-) 486 WP_234365471.1 cupin domain-containing protein -
  A7B19_RS43655 - 10259532..10260215 (-) 684 WP_267893872.1 aldehyde dehydrogenase family protein -
  A7B19_RS43660 - 10260458..10261633 (+) 1176 WP_063736445.1 sensor histidine kinase -
  A7B19_RS43665 vraR 10261630..10262340 (+) 711 WP_063736443.1 response regulator Regulator
  A7B19_RS43670 - 10262437..10263603 (+) 1167 WP_063736441.1 serine hydrolase domain-containing protein -
  A7B19_RS43675 - 10263600..10264808 (-) 1209 WP_063736438.1 cytochrome P450 -
  A7B19_RS43680 - 10264982..10265413 (-) 432 WP_199844354.1 MerR family transcriptional regulator -
  A7B19_RS43685 - 10265466..10266416 (+) 951 WP_063736434.1 SDR family NAD(P)-dependent oxidoreductase -
  A7B19_RS43690 - 10266487..10267128 (+) 642 WP_063736432.1 TetR/AcrR family transcriptional regulator -

Sequence

Protein


Download         Length: 236 a.a.        Molecular weight: 25093.55 Da        Isoelectric Point: 5.6735

>NTDB_id=154666 A7B19_RS43665 WP_063736443.1 10261630..10262340(+) (vraR) [Streptomyces sp. RTd22]
MSIRVVVADDQELVRSGFSMILDAQPDIEVVAEAGDGSEAVAAVRRYTPDVALLDIRMPGMDGIAACREISADGACRTVM
LTTFDSDEYVYDALHAGASGFLLKDVRRDDLVHAVRVVARGDSLLAPSVARRLVEQYTRPAARSRRPDPRLDALTGRERE
TLLLLARGLSNAEIAAELVVSDHTVKTHVGHVLAKLGLRDRIQAVICAYETGLVTAGDPPPGGASGPGSSPASARK

Nucleotide


Download         Length: 711 bp        

>NTDB_id=154666 A7B19_RS43665 WP_063736443.1 10261630..10262340(+) (vraR) [Streptomyces sp. RTd22]
GTGAGCATCCGGGTGGTGGTGGCCGACGACCAGGAGCTGGTGCGCAGCGGCTTCTCGATGATCCTGGACGCCCAGCCGGA
CATCGAGGTGGTCGCGGAGGCGGGCGACGGATCCGAGGCGGTCGCGGCCGTACGGCGGTACACGCCCGATGTGGCGCTGC
TCGACATCCGGATGCCGGGCATGGACGGCATCGCGGCCTGCCGCGAGATCAGCGCCGACGGCGCCTGCCGGACGGTGATG
CTGACGACCTTCGACTCGGACGAGTACGTGTACGACGCGCTGCACGCGGGCGCGAGCGGCTTCCTGCTGAAGGACGTACG
CCGGGACGACCTGGTGCACGCGGTACGGGTGGTGGCGCGGGGCGACTCGCTGCTCGCGCCGTCCGTGGCCCGCCGCCTGG
TCGAGCAGTACACCCGCCCGGCCGCCCGATCGCGGCGGCCCGATCCCCGTCTGGACGCGCTGACCGGGCGGGAGCGGGAG
ACGCTGCTGCTGCTCGCGCGGGGCCTGTCGAACGCCGAGATCGCGGCGGAGCTGGTCGTCAGCGACCACACGGTCAAAAC
GCATGTCGGCCATGTGCTCGCCAAGCTGGGTCTGCGGGACCGGATCCAGGCGGTGATCTGCGCGTACGAAACGGGCCTGG
TCACGGCCGGGGATCCGCCGCCCGGGGGAGCGTCCGGGCCCGGATCATCCCCCGCGTCGGCGAGGAAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(153-208)

Response regulator receiver domain (Response_reg)

(5-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

42.326

91.102

0.386
  degU Bacillus subtilis subsp. subtilis str. 168

39.732

94.915

0.377

Multiple sequence alignment