Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   A7B19_RS10470 Genome accession   NZ_CP015726
Coordinates   2731035..2731691 (-) Length   218 a.a.
NCBI ID   WP_063731841.1    Uniprot ID   -
Organism   Streptomyces sp. RTd22     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2726035..2736691
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A7B19_RS10440 - 2726650..2727153 (+) 504 WP_009718997.1 HNH endonuclease -
  A7B19_RS10445 - 2727225..2728193 (-) 969 WP_063731839.1 SPFH domain-containing protein -
  A7B19_RS10450 - 2728331..2728756 (-) 426 WP_009718995.1 NfeD family protein -
  A7B19_RS10455 - 2728863..2729654 (-) 792 WP_009718994.1 ABC transporter ATP-binding protein -
  A7B19_RS10460 - 2729765..2730568 (+) 804 WP_009718993.1 hypothetical protein -
  A7B19_RS10465 - 2730669..2730899 (-) 231 WP_009718992.1 chaplin -
  A7B19_RS10470 vraR 2731035..2731691 (-) 657 WP_063731841.1 response regulator Regulator
  A7B19_RS10475 - 2731684..2732841 (-) 1158 WP_063731844.1 GAF domain-containing sensor histidine kinase -
  A7B19_RS10480 - 2733299..2734069 (+) 771 WP_063731847.1 hypothetical protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23504.79 Da        Isoelectric Point: 5.6958

>NTDB_id=154594 A7B19_RS10470 WP_063731841.1 2731035..2731691(-) (vraR) [Streptomyces sp. RTd22]
MGERRDGAAIRVLLVDDHQVVRRGLRTFLEVQDDIDVVGEAADGEEGIARAEELRPDIVLMDVKMPGIDGIEALRKLRDL
GNPARVLVVTSFTEKRTVVPALRAGAAGYVYKDVDPDALASAIRSVHAGHVVLQPEVADALLSQDEAGGGQGRGGSLTDR
EREVLGLIADGRSNREIARRLVLSEKTVKTHVSNILMKLDLADRTQAALWAVRHGIGA

Nucleotide


Download         Length: 657 bp        

>NTDB_id=154594 A7B19_RS10470 WP_063731841.1 2731035..2731691(-) (vraR) [Streptomyces sp. RTd22]
GTGGGTGAGCGACGGGACGGAGCGGCGATCCGGGTGCTGCTCGTCGACGACCACCAGGTGGTGCGGCGCGGTCTGCGGAC
CTTCCTGGAGGTGCAGGACGACATCGACGTGGTCGGCGAGGCCGCGGACGGGGAGGAGGGCATCGCCCGGGCCGAGGAGC
TGCGCCCCGACATCGTCCTGATGGACGTCAAGATGCCCGGCATCGACGGCATCGAGGCGCTGCGCAAACTGCGTGACCTG
GGCAACCCGGCCCGGGTACTGGTCGTGACGAGTTTCACCGAGAAGCGCACCGTGGTCCCCGCCCTGCGCGCGGGCGCGGC
CGGTTACGTCTACAAGGACGTGGACCCCGATGCCCTCGCCAGCGCCATACGGTCCGTCCACGCCGGGCATGTGGTGCTCC
AGCCCGAGGTGGCCGACGCGCTGCTCTCCCAGGACGAGGCGGGCGGCGGCCAGGGGCGCGGGGGTTCCCTCACCGACCGG
GAGCGGGAGGTGCTGGGGCTGATCGCGGACGGCCGCTCGAACCGGGAGATCGCGCGCAGGCTCGTACTGTCCGAAAAGAC
CGTAAAGACACATGTGTCCAATATTCTTATGAAGTTGGACCTGGCCGACCGCACTCAGGCCGCACTCTGGGCGGTACGCC
ACGGAATCGGGGCATGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(12-123)

Bacterial regulatory proteins, luxR family (GerE)

(156-211)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

44.231

95.413

0.422
  degU Bacillus subtilis subsp. subtilis str. 168

36.652

100

0.372

Multiple sequence alignment